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ABHD6 (NM_020676) Human Untagged Clone
CAT＃: SC320252
ABHD6 (untagged)-Human abhydrolase domain containing 6 (ABHD6)
CNY 5,488.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_020676.4
GCCCGGCGGCAGGTCCCAGCCCGGGGCTAGAGACCGAGGGCCGGGGTCCGGGCCCGGCGG
CGGGACCCAGGCGGTTGAGGCTGGTCAGGAGTCAGCCAGCCTGAAAGAGCAGGATGGATC TTGATGTGGTTAACATGTTTGTGATTGCGGGCGGCACGCTGGCCATCCCAATCCTGGCAT TTGTGGCTTCATTTCTTCTGTGGCCTTCAGCACTGATAAGAATCTATTATTGGTACTGGC GGAGGACATTGGGCATGCAAGTCCGCTATGTTCACCATGAAGACTATCAGTTCTGTTATT CCTTCCGGGGCAGGCCTGGGCACAAACCCTCCATCCTCATGCTCCACGGATTCTCTGCCC ACAAGGATATGTGGCTCAGTGTGGTCAAGTTCCTTCCAAAGAACCTGCACTTGGTCTGCG TGGACATGCCAGGACATGAGGGCACCACCCGCTCCTCCCTGGATGACCTGTCCATAGATG GGCAAGTTAAGAGGATACACCAGTTTGTAGAATGCCTGAAGCTGAACAAAAAACCTTTCC ACCTGGTAGGCACCTCCATGGGTGGCCAGGTGGCTGGGGTGTATGCTGCTTACTACCCAT CGGATGTCTCCAGCCTGTGTCTCGTGTGTCCTGCTGGCCTGCAGTACTCAACTGACAATC AATTTGTACAACGGCTCAAAGAACTGCAGGGCTCTGCCGCCGTGGAGAAGATTCCCTTGA TCCCGTCTACCCCAGAAGAGATGAGTGAAATGCTTCAGCTCTGCTCCTATGTCCGCTTCA AGGTGCCCCAGCAGATCCTGCAAGGCCTTGTCGATGTCCGCATCCCTCATAACAACTTCT ACCGAAAGTTGTTTTTGGAAATCGTCAGTGAGAAGTCCAGATACTCTCTCCATCAGAACA TGGACAAGATCAAGGTTCCGACGCAGATCATCTGGGGGAAACAAGACCAGGTGCTGGATG TGTCTGGGGCAGACATGTTGGCCAAGTCAATTGCCAACTGCCAGGTGGAGCTTCTGGAAA ACTGTGGGCACTCAGTAGTGATGGAAAGACCCAGGAAGACAGCCAAGCTCATAATCGACT TTTTAGCTTCTGTGCACAACACAGACAACAACAAGAAGCTGGACTGAGGCCCCGACTGCA GCCTGCATTCTGCACACAGCATCTGCTCCCATCCCCCAAGTCTGACGCAGCCACCACTCT CAGGGATCCTGCCCCAAATGCGGTCGGAGCGCCAGTGACCCTGAGGAAGCCCGTCCCTTA TCCCTGGTATCCACGGTTCCCCAGAGCTTTGGGGACCACGCGAAAACCTCCAAGATATTT TTCACAAAATAGAAACTCATATGGAACAAAATAAGAAACCCCAGCCATGAAATCTACCAT GAAGTCTTCAAGTTCATGTCACTGAGAAGCTTGTGCAAAGCAGCCACCTTGGACCATAAT TAAATCAAGGACATTTTCTTTGAGACATTCCTTATAGTTGGAGACTCAAGATATTTTTGT TGCATCAGGTGTATTCCCTTGCATGGGCAGTGGCTTTTATAGGAGCATTAGTCCTCATTC GCTGAACCCTGTTGTTTAGGTCTAATTTAAGTTTTACATAGAGACCCATGTATGACTGCA GCCCATTGGCTGCAAGACCAGGGAGGAAAGTGGCAAGCTGTAGAAAATGTTTACACGCAT GGAGGGGCATTGCTCTAGCCCTCAGAGCGTCCGGAGCAGCAGGGTACATGGGTGGGAGGT TCATTCAGCACCCACCAGTCAGGTATGTTCTGAGTGAACCCACAGCAGTCGCAGAATGAG CACCTGGCAGGGTGGGTTTCCTAGGAATAATTTATTATTTTTAAAAATAGGCCTAATAAA GCAATAATGTTCTAGACATCTGTCTAAGTAATCAGACTCAGGTTCCACACACAAGCAACA ACTCGTGGGCCTCTTTTCTATTTCAATGTGCTACTAAGAACCCTTGGATGTAACATACTA GTTAGTTAATGAATTCTGTGAATTCTGTGAAGAGTAATGTGATTGAAAATAAGTCTAAAC AGCTGTAAAAGTGACCACAATGACATGAAATAAATTTAATAAGTCTAGATCAGCAAAAAA AAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_020676 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_020676.4, NP_065727.3 |
| RefSeq Size | 2364 bp |
| RefSeq ORF | 1014 bp |
| Locus ID | 57406 |
| UniProt ID | Q9BV23 |
| Domains | abhydrolase |
| Protein Families | Transmembrane |
| Gene Summary | Lipase that preferentially hydrolysis medium-chain saturated monoacylglycerols including 2-arachidonoylglycerol (PubMed:22969151). Through 2-arachidonoylglycerol degradation may regulate endocannabinoid signaling pathways (By similarity). Also has a lysophosphatidyl lipase activity with a preference for lysophosphatidylglycerol among other lysophospholipids (By similarity). Also able to degrade bis(monoacylglycero)phosphate (BMP) and constitutes the major enzyme for BMP catabolism (PubMed:26491015). BMP, also known as lysobisphosphatidic acid, is enriched in late endosomes and lysosomes and plays a key role in the formation of intraluminal vesicles and in lipid sorting (PubMed:26491015).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein. |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Simplified assays of lipolysis enzymes for drug discovery and specificity assessment of known inhibitors
,null,
Journal of Lipid Research
,PubMed ID 26423520
[ABHD6]
|
|
Robust Hydrolysis of Prostaglandin Glycerol Esters by Human Monoacylglycerol Lipase (MAGL)
,Savinainen, JR;Kansanen, E;Pantsar, T;Navia-Paldanius, D;Parkkari, T;Lehtonen, M;Laitinen, T;Nevalainen, T;Poso, A;Levonen, AL;Laitinen, JT;,
Mol. Pharmacol.
,PubMed ID 25140003
[ABHD6]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200915 | ABHD6 (Myc-DDK-tagged)-Human abhydrolase domain containing 6 (ABHD6) |
CNY 5,488.00 |
|
| RC200915L3 | Lenti ORF clone of Human abhydrolase domain containing 6 (ABHD6), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC200915L4 | Lenti ORF clone of Human abhydrolase domain containing 6 (ABHD6), mGFP tagged |
CNY 5,890.00 |
|
| RG200915 | ABHD6 (tGFP-tagged) - Human abhydrolase domain containing 6 (ABHD6) |
CNY 7,088.00 |
