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PAR4 (PAWR) (NM_002583) Human Untagged Clone
CAT＃: SC320836
PAWR (untagged)-Human PRKC, apoptosis, WT1, regulator (PAWR)
CNY 3,656.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | Par-4; PAR4 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_002583 edited
TGGGAGCGGCGGCCGTCCCTCTCCTGGAGGTCGTCTCCTGGCATCCTCGGGGCCGCAGGA AGGAAGAGGAGGCAGCGGCCGGAGCCCTGGTGGGCGGCCTGAGGTGAGAGCCCGACCGGC CCCTTTGGGAATATGGCGACCGGTGGCTACCGGACCAGCAGCGGCCTCGGCGGCAGCACC ACAGACTTCCTGGAGGAGTGGAAGGCGAAACGCGAGAAGATGCGCGCCAAGCAGAACCCC CCGGGCCCGGCCCCCCCGGGAGGGGGCAGCAGCGACGCCGCTGGGAAGCCCCCCGCGGGG GCTCTGGGCACCCCGGCGGCCGCCGCTGCCAACGAGCTCAACAACAACCTCCCGGGCGGC GCGCCGGCCGCACCTGCCGTCCCCGGTCCCGGGGGCGTGAACTGCGCGGTCGGCTCCGCC ATGCTGACGCGGGCGGCCCCCGGCCCGCGGCGGTCGGAGGACGAGCCCCCAGCCGCCTCT GCCTCGGCTGCACCGCCGCCCCAGCGTGACGAGGAGGAGCCGGACGGCGTCCCAGAGAAG GGCAAGAGCTCGGGCCCCAGTGCCAGGAAAGGCAAGGGGCAGATCGAGAAGAGGAAGCTG CGGGAGAAGCGGCGCTCCACCGGCGTGGTCAACATCCCTGCCGCAGAGTGCTTAGATGAG TACGAAGATGATGAAGCAGGGCAGAAAGAGCGGAAACGAGAAGATGCAATTACACAACAG AACACTATACAGAATGAAGCTGTAAACTTACTAGATCCAGGCAGTTCCTATCTGCTACAG GAGCCACCTAGAACAGTTTCAGGCAGATATAAAAGCACAACCAGTGTCTCTGAAGAAGAT GTCTCAAGTAGATATTCTCGAACAGATAGAAGTGGGTTCCCTAGATATAACAGGGATGCA AATGTTTCAGGTACTCTGGTTTCAAGTAGCACACTGGAAAAGAAAATTGAAGATCTTGAA AAGGAAGTAGTAAGAGAAAGACAAGAAAACCTAAGACTTGTGAGACTGATGCAAGATAAA GAGGAAATGATTGGAAAACTCAAAGAAGAAATTGATTTATTAAATAGAGACCTAGATGAC ATAGAAGATGAAAATGAACAGCTAAAGCAGGAAAATAAAACTCTTTTGAAAGTTGTGGGT CAGCTGACCAGGTAGAGGATTCAAGACTCAATGTGGAAAAAATATTTTAAACTACTGATT GAATGTTAATGGTCAATGCTAGCACAATATTCCTATGCTGCAATACATTAAAATAACTAA GCAAGTATATTTATTTCTAGCAAACAGATGTTTGTTTTCAAAATACTTCTTTTTCATTAT TGGTTTTAAAAAAGCATTATCCTTTTATCTCACAAATAAGTAATATCTTTCAGTTATTAA ATGATAGATAATGCCTTTTTGGTTTTGTGTGGTATTCAACTAATACATGGTTTAAAGTCA CAGCCGTTTGAATATATTTTATCTTGGTAGTACATTTTCTCCCTTAGGAATATACATAGT CTTTGTTTTACATGAGTTCAAATACTTTTGGGATGTTACCTTCACATGTCCTATTACTGA TGTGTGCAACCTTTTATGTGTTGATGACTCACTCATAAAGGTTTTTGTCTACTGTCATTT GTTCTTTCCACTTATTCTAAGCATTTAGAGTAATAGAGTCATACTTTTTTATAACAGCAA CCTTTTAAAAGGAAAGCTCTTATAAAGTCACTGTCATGTTTTAGTTGACTAAATATAAAT TTAAGAGAATACTTGAATTGTGCTATAGTAAATAAAAATTTACTATTTTGTGTTTGATAA AAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_002583 |
| Insert Size | 1800 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_002583.2, NP_002574.2 |
| RefSeq Size | 1967 bp |
| RefSeq ORF | 1023 bp |
| Locus ID | 5074 |
| UniProt ID | Q96IZ0 |
| Protein Families | Druggable Genome, Transcription Factors |
| Gene Summary | This gene encodes a tumor suppressor protein that selectively induces apoptosis in cancer cells through intracellular and extracellular mechanisms. The intracellular mechanism involves the inhibition of pro-survival pathways and the activation of Fas-mediated apoptosis, while the extracellular mechanism involves the binding of a secreted form of this protein to glucose regulated protein 78 (GRP78) on the cell surface, which leads to activation of the extrinsic apoptotic pathway. This gene is located on the unstable human chromosomal 12q21 region and is often deleted or mutated different tumors. The encoded protein also plays an important role in the progression of age-related diseases. [provided by RefSeq, Aug 2017] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202733 | PAWR (Myc-DDK-tagged)-Human PRKC, apoptosis, WT1, regulator (PAWR) |
CNY 3,656.00 |
|
| RC202733L1 | Lenti ORF clone of Human PRKC, apoptosis, WT1, regulator (PAWR), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC202733L2 | Lenti ORF clone of Human PRKC, apoptosis, WT1, regulator (PAWR), mGFP tagged |
CNY 5,890.00 |
|
| RC202733L3 | Lenti ORF clone of Human PRKC, apoptosis, WT1, regulator (PAWR), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC202733L4 | Lenti ORF clone of Human PRKC, apoptosis, WT1, regulator (PAWR), mGFP tagged |
CNY 6,056.00 |
|
| RG202733 | PAWR (tGFP-tagged) - Human PRKC, apoptosis, WT1, regulator (PAWR) |
CNY 5,256.00 |
|
| SC110969 | PAWR (untagged)-Human PRKC, apoptosis, WT1, regulator (PAWR) |
CNY 3,656.00 |
