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CX3CL1 (NM_002996) Human Untagged Clone
CAT＃: SC321351
CX3CL1 (untagged)-Human chemokine (C-X3-C motif) ligand 1 (CX3CL1)
CNY 3,656.00
| Cited in 1 publication. |
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热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ABCD-3; C3Xkine; CXC3; CXC3C; fractalkine; neurotactin; NTN; NTT; SCYD1 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_002996.3
CTGAGCTCTGCCGCCTGGCTCTAGCCGCCTGCCTGGCCCCCGCCGGGACTCTTGCCCACC
CTCAGCCATGGCTCCGATATCTCTGTCGTGGCTGCTCCGCTTGGCCACCTTCTGCCATCT GACTGTCCTGCTGGCTGGACAGCACCACGGTGTGACGAAATGCAACATCACGTGCAGCAA GATGACATCAAAGATACCTGTAGCTTTGCTCATCCACTATCAACAGAACCAGGCATCATG CGGCAAACGCGCAATCATCTTGGAGACGAGACAGCACAGGCTGTTCTGTGCCGACCCGAA GGAGCAATGGGTCAAGGACGCGATGCAGCATCTGGACCGCCAGGCTGCTGCCCTAACTCG AAATGGCGGCACCTTCGAGAAGCAGATCGGCGAGGTGAAGCCCAGGACCACCCCTGCCGC CGGGGGAATGGACGAGTCTGTGGTCCTGGAGCCCGAAGCCACAGGCGAAAGCAGTAGCCT GGAGCCGACTCCTTCTTCCCAGGAAGCACAGAGGGCCCTGGGGACCTCCCCAGAGCTGCC GACGGGCGTGACTGGTTCCTCAGGGACCAGGCTCCCCCCGACGCCAAAGGCTCAGGATGG AGGGCCTGTGGGCACGGAGCTTTTCCGAGTGCCTCCCGTCTCCACTGCCGCCACGTGGCA GAGTTCTGCTCCCCACCAACCTGGGCCCAGCCTCTGGGCTGAGGCAAAGACCTCTGAGGC CCCGTCCACCCAGGACCCCTCCACCCAGGCCTCCACTGCGTCCTCCCCAGCCCCAGAGGA GAATGCTCCGTCTGAAGGCCAGCGTGTGTGGGGTCAGGGACAGAGCCCCAGGCCAGAGAA CTCTCTGGAGCGGGAGGAGATGGGTCCCGTGCCAGCGCACACGGATGCCTTCCAGGACTG GGGGCCTGGCAGCATGGCCCACGTCTCTGTGGTCCCTGTCTCCTCAGAAGGGACCCCCAG CAGGGAGCCAGTGGCTTCAGGCAGCTGGACCCCTAAGGCTGAGGAACCCATCCATGCCAC CATGGACCCCCAGAGGCTGGGCGTCCTTATCACTCCTGTCCCTGACGCCCAGGCTGCCAC CCGGAGGCAGGCGGTGGGGCTGCTGGCCTTCCTTGGCCTCCTCTTCTGCCTGGGGGTGGC CATGTTCACCTACCAGAGCCTCCAGGGCTGCCCTCGAAAGATGGCAGGAGAGATGGCGGA GGGCCTTCGCTACATCCCCCGGAGCTGTGGTAGTAATTCATATGTCCTGGTGCCCGTGTG AACTCCTCTGGCCTGTGTCTAGTTGTTTGATTCAGACAGCTGCCTGGGATCCCTCATCCT CATACCCACCCCCACCCAAGGGCCTGGCCTGAGCTGGGATGATTGGAGGGGGGAGGTGGG ATCCTCCAGGTGCACAAGCTCCAAGCTCCCAGGCATTCCCCAGGAGGCCAGCCTTGACCA TTCTCCACCTTCCAGGGACAGAGGGGGTGGCCTCCCAACTCACCCCAGCCCCAAAACTCT CCTCTGCTGCTGGCTGGTTAGAGGTTCCCTTTGACGCCATCCCAGCCCCAATGAACAATT ATTTATTAAATGCCCAGCCCCTTCTGACCCATGCTGCCCTGTGAGTACTACAGTCCTCCC ATCTCACACATGAGCATCAGGCCAGGCCCTCTGCCCACTCCCTGCAACCTGATTGTGTCT CTTGGTCCTGCTGCAGTTGCCAGTCACCCCGGCCACCTGCGGTGCTATCTCCCCCAGCCC CATCCTCTGTACAGAGCCCACGCCCCCACTGGTGACATGTCTTTTCTTGCATGAGGCTAG TGTGGTGTTTCCTGGCACTGCTTCCAGTGAGGCTCTGCCCTTGGTTAGGCATTGTGGGAA GGGGAGATAAGGGTATCTGGTGACTTTCCTCTTTGGTCTACACTGTGCTGAGTCTGAAGG CTGGGTTCTGATCCTAGTTCCACCATCAAGCCACCAACATACTCCCATCTGTGAAAGGAA AGAGGGAGGTAAGGAATACCTGTCCCCCTGACAACACTCATTGACCTGAGGCCCTTCTCT CCAGCCCCTGGATGCAGCCTCACAGTCCTTACCAGCAGAGCACCTTAGACAGTCCCTGCC AATGGACTAACTTGTCTTTGGACCCTGAGGCCCAGAGGGCCTGCAAGGGAGTGAGTTGAT AGCACAGACCCTGCCCTGTGGGCCCCCAAATGGAAATGGGCAGAGCAGAGACCATCCCTG AAGGCCCCGCCCAGGCTTAGTCACTGAGACAGCCCGGGCTCTGCCTCCCATCACCCGCTA AGAGGGAGGGAGGGCTCCAGACACATGTCCAAGAAGCCCAGGAAAGGCTCCAGGAGCAGC CACATTCCTGATGCTTCTTCAGAGACTCCTGCAGGCAGCCAGGCCACAAGACCCTTGTGG TCCCACCCCACACACGCCAGATTCTTTCCTGAGGCTGGGCTCCCTTCCCACCTCTCTCAC TCCTTGAAAACACTGTTCTCTGCCCTCCAAGACCTTCTCCTTCACCTTTGTCCCCACCGC AGACAGGACCAGGGATTTCCATGATGTTTTCCATGAGTCCCCTGTTTGTTTCTGAAAGGG ACGCTACCCGGGAAGGGGGCTGGGACATGGGAAAGGGGAAGTTGTAGGCATAAAGTCAGG GGTTCCCTTTTTTGGCTGCTGAAGGCTCGAGCATGCCTGGATGGGGCTGCACCGGCTGGC CTGGCCCCTCAGGGTCCCTGGTGGCAGCTCACCTCTCCCTTGGATTGTCCCCGACCCTTG CCGTCTACCTGAGGGGCCTCTTATGGGCTGGGTTCTACCCAGGTGCTAGGAACACTCCTT CACAGATGGGTGCTTGGAGGAAGGAAACCCAGCTCTGGTCCATAGAGAGCAAGACGCTGT GCTGCCCTGCCCACCTGGCCTCTGCACTCCCCTGCTGGGTGTGGCGCAGCATATTCAGGA AGCTCAGGGCCTGGCTCAGGTGGGGTCACTCTGGCAGCTCAGAGAGGGTGGGAGTGGGTC CAATGCACTTTGTTCTGGCTCTTCCAGGCTGGGAGAGCCTTTCAGGGGTGGGACACCCTG TGATGGGGCCCTGCCTCCTTTGTGAGGAAGCCGCTGGGGCCAGTTGGTCCCCCTTCCATG GACTTTGTTAGTTTCTCCAAGCAGGACATGGACAAGGATGATCTAGGAAGACTTTGGAAA GAGTAGGAAGACTTTGGAAAGACTTTTCCAACCCTCATCACCAACGTCTGTGCCATTTTG TATTTTACTAATAAAATTTAAAAGTCTTGTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_002996 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002996.3, NP_002987.1 |
| RefSeq Size | 3304 bp |
| RefSeq ORF | 1194 bp |
| Locus ID | 6376 |
| UniProt ID | P78423 |
| Domains | IL8 |
| Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
| Protein Pathways | Chemokine signaling pathway, Cytokine-cytokine receptor interaction |
| Gene Summary | This gene belongs to the CX3C subgroup of chemokines, characterized by the number of amino acids located between the conserved cysteine residues. This is the only member of the CX3C subgroup, which contains three amino acids between cysteine residues, resulting in a Cys-X-X-X-Cys configuration. The encoded protein contains an extended mucin-like stalk with a chemokine domain on top, and exists in both a membrane-anchored form where it acts as a binding molecule, or, in soluble form, as a chemotactic cytokine. The mature form of this protein can be cleaved at the cell surface, yielding different soluble forms that can interact with the G-protein coupled receptor, C-X3-C motif chemokine receptor 1 gene product. This gene plays a role in a wide range of diseases, including cancer, vasculitis, neuropathies, atherosclerosis, inflammatory diseases, and in human immunodeficiency virus infections. [provided by RefSeq, Sep 2017] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Fractalkine/CX3CR1 induces apoptosis resistance and proliferation through the activation of the AKT/NF-κB cascade in pancreatic cancer cells.
,null,
Cell biochemistry and function
,PubMed ID 28845524
[CX3CL1]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200420 | CX3CL1 (Myc-DDK-tagged)-Human chemokine (C-X3-C motif) ligand 1 (CX3CL1) |
CNY 3,656.00 |
|
| RC200420L1 | Lenti-ORF clone of CX3CL1 (Myc-DDK-tagged)-Human chemokine (C-X3-C motif) ligand 1 (CX3CL1) |
CNY 6,056.00 |
|
| RC200420L2 | Lenti-ORF clone of CX3CL1 (mGFP-tagged)-Human chemokine (C-X3-C motif) ligand 1 (CX3CL1) |
CNY 5,890.00 |
|
| RC200420L3 | Lenti-ORF clone of CX3CL1 (Myc-DDK-tagged)-Human chemokine (C-X3-C motif) ligand 1 (CX3CL1) |
CNY 6,056.00 |
|
| RC200420L4 | Lenti-ORF clone of CX3CL1 (mGFP-tagged)-Human chemokine (C-X3-C motif) ligand 1 (CX3CL1) |
CNY 6,056.00 |
|
| RG200420 | CX3CL1 (tGFP-tagged) - Human chemokine (C-X3-C motif) ligand 1 (CX3CL1) |
CNY 5,256.00 |
