hnRNP K (HNRNPK) (NM_002140) Human Untagged Clone
CAT#: SC321563
HNRNPK (untagged)-Human heterogeneous nuclear ribonucleoprotein K (HNRNPK), transcript variant 1
CNY 3,656.00
Cited in 2 publications. |
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | AUKS; CSBP; HNRPK; TUNP |
Vector | pCMV6-AC |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>OriGene sequence for NM_002140.2
CGGCAGTCTCGCGCGGCTACTGCAGCACTGGGGTGTCAGTTGTTGGTCCGACCCAGAACG
CTTCAGTTCTGCTCTGCAAGGATATATAATAACTGATTGGTGTGCCCGTTTAATAAAAGA ATATGGAAACTGAACAGCCAGAAGAAACCTTCCCTAACACTGAAACCAATGGTGAATTTG GTAAACGCCCTGCAGAAGATATGGAAGAGGAACAAGCATTTAAAAGATCTAGAAACACTG ATGAGATGGTTGAATTACGCATTCTGCTTCAGAGCAAGAATGCTGGGGCAGTGATTGGAA AAGGAGGCAAGAATATTAAGGCTCTCCGTACAGACTACAATGCCAGTGTTTCAGTCCCAG ACAGCAGTGGCCCCGAGCGCATATTGAGTATCAGTGCTGATATTGAAACAATTGGAGAAA TTCTGAAGAAAATCATCCCTACCTTGGAAGAGGGCCTGCAGTTGCCATCACCCACTGCAA CCAGCCAGCTCCCGCTCGAATCTGATGCTGTGGAATGCTTAAATTACCAACACTATAAAG GAAGTGACTTTGACTGCGAGTTGAGGCTGTTGATTCATCAGAGTCTAGCAGGAGGAATTA TTGGGGTCAAAGGTGCTAAAATCAAAGAACTTCGAGAGAACACTCAAACCACCATCAAGC TTTTCCAGGAATGCTGTCCTCATTCCACTGACAGAGTTGTTCTTATTGGAGGAAAACCCG ATAGGGTTGTAGAGTGCATAAAGATCATCCTTGATCTTATATCTGAGTCTCCCATCAAAG GACGTGCACAGCCTTATGATCCCAATTTTTACGATGAAACCTATGATTATGGTGGTTTTA CAATGATGTTTGATGACCGTCGCGGACGCCCAGTGGGATTTCCCATGCGGGGAAGAGGTG GTTTTGACAGAATGCCTCCTGGTCGGGGTGGGCGTCCCATGCCTCCATCTAGAAGAGATT ATGATGATATGAGCCCTCGTCGAGGACCACCTCCCCCTCCTCCCGGACGAGGCGGCCGGG GTGGTAGCAGAGCTCGGAATCTTCCTCTTCCTCCACCACCACCACCTAGAGGGGGAGACC TCATGGCCTATGACAGAAGAGGGAGACCTGGAGACCGTTACGACGGCATGGTTGGTTTCA GTGCTGATGAAACTTGGGACTCTGCAATAGATACATGGAGCCCATCAGAATGGCAGATGG CTTATGAACCACAGGGTGGCTCCGGATATGATTATTCCTATGCAGGGGGTCGTGGCTCAT ATGGTGATCTTGGTGGACCTATTATTACTACACAAGTAACTATTCCCAAAGATTTGGCTG GATCTATTATTGGCAAAGGTGGTCAGCGGATTAAACAAATCCGTCATGAGTCGGGAGCTT CGATCAAAATTGATGAGCCTTTAGAAGGATCCGAAGATCGGATCATTACCATTACAGGAA CACAGGACCAGATACAGAATGCACAGTATTTGCTGCAGAACAGTGTGAAGCAGTATGCAG ATGTTGAAGGATTCTAATGCAAGATATTTTTTCTTTTTTATAGTGTGAAGCAGTATTCTG GAAAGTTTTTCTAAGACTAGTGAAGAACTGAAGGAGTCCTGCATCTTTTTTTTTTTATCT GCTTCTGTTTAAAAAGCCAACATTCCTCTGCTTCATAGGTGTTCTGCATTTGAGGTGTAG TGAAATCTTTGCTGTTCACCAGATGTAATGTTTTAGTTCCTTACAAACAGGGTTGGGGGG GGGAAGGGCGTGCAAAAACTAACATTGAAATTTTGAAACAGCAGCAGAGTGAGTGGATTT TATTTTTCGTTATTGTTGGTGGTTTAAAAAATTCCCCCCATGTAATTATTGTGAACACCT TGCTTTGTGGTCACTGTAACATTTGGGGGGTGGGACAGGGAGGAAAAGTAACAATAGTCC ACATGTCCCTGGCATCTGTTCAGAGCAGTGTGCAGAATGTAATGCTCTTTTGTAAGAAAC GTTTTATGATTTTTAAAATAAATTTAGTGAACCTAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAA |
Restriction Sites | Please inquire |
ACCN | NM_002140 |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_002140.2, NP_002131.2 |
RefSeq Size | 2830 bp |
RefSeq ORF | 1395 bp |
Locus ID | 3190 |
UniProt ID | P61978 |
Domains | KH |
Protein Pathways | Spliceosome |
Gene Summary | This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference; it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Transcript variants 1 and 2 encode the same isoform (a). |
Citations (2)
The use of this cDNA Clones has been cited in the following citations: |
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Regulation of C-X-C chemokine gene expression by keratin 17 and hnRNP K in skin tumor keratinocytes
,Chung, BM;Arutyunov, A;Ilagan, E;Yao, N;Wills-Karp, M;Coulombe, PA;,
J. Cell Biol.
,PubMed ID 25713416
[HNRNPK]
|
How does keratin 17 control gene expression?
,Arutyunov, AD;,
Thesis
[HNRNPK]
|
Documents
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC201843 | HNRNPK (Myc-DDK-tagged)-Human heterogeneous nuclear ribonucleoprotein K (HNRNPK), transcript variant 1 |
CNY 3,656.00 |
|
RC201843L1 | Lenti ORF clone of Human heterogeneous nuclear ribonucleoprotein K (HNRNPK), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
|
RC201843L2 | Lenti ORF clone of Human heterogeneous nuclear ribonucleoprotein K (HNRNPK), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
RC201843L3 | Lenti ORF clone of Human heterogeneous nuclear ribonucleoprotein K (HNRNPK), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
|
RC201843L4 | Lenti ORF clone of Human heterogeneous nuclear ribonucleoprotein K (HNRNPK), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
RG201843 | HNRNPK (tGFP-tagged) - Human heterogeneous nuclear ribonucleoprotein K (HNRNPK), transcript variant 1 |
CNY 5,256.00 |
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