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Cytochrome p450 2J2 (CYP2J2) (NM_000775) Human Untagged Clone
CAT＃: SC321730
CYP2J2 (untagged)-Human cytochrome P450, family 2, subfamily J, polypeptide 2 (CYP2J2)
CNY 3,744.00
| Cited in 7 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CPJ2; CYPIIJ2 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_000775.2
CCACGCGTCCGCGCCGCCTGCTTGGACCGCAGAAGAGCAGGAGGACGTCTGAGCCATGCT
CGCGGCGATGGGCTCTCTGGCGGCTGCCCTCTGGGCAGTGGTCCATCCTCGGACTCTCCT ACTGGGCACTGTCGCCTTTCTGCTCGCTGCTGACTTTCTCAAAAGACGGCGCCCAAAGAA CTACCCGCCGGGGCCCTGGCGCCTGCCCTTCCTTGGCAACTTCTTCCTTGTGGACTTCGA GCAGTCGCACCTGGAGGTTCAGCTGTTTGTGAAGAAATATGGGAACCTTTTTAGCTTGGA GCTTGGTGACATATCTGCAGTTCTTATTACTGGCTTGCCCTTAATCAAAGAAGCCCTTAT CCACATGGACCAAAACTTTGGGAACCGCCCCGTGACCCCTATGCGAGAACATATCTTTAA GAAAAATGGATTGATTATGTCAAGTGGCCAGGCATGGAAGGAGCAAAGAAGGTTCACTCT GACAGCACTAAGGAACTTTGGTTTAGGAAAGAAGAGCTTAGAGGAACGCATTCAGGAGGA GGCCCAACACCTCACTGAAGCAATAAAAGAGGAGAACGGACAGCCTTTTGACCCTCATTT CAAGATCAACAATGCAGTTTCCAATATCATTTGCTCCATCACCTTCGGAGAACGCTTTGA GTACCAGGATAGTTGGTTTCAGCAGCTGCTGAAGTTACTAGATGAAGTCACATACTTGGA GGCTTCAAAGACATGCCAGCTCTACAATGTCTTTCCATGGATAATGAAATTCCTGCCTGG ACCCCACCAAACTCTCTTCAGCAACTGGAAAAAACTGAAATTGTTTGTTTCTCATATGAT TGACAAACACAGAAAGGATTGGAATCCTGCAGAAACAAGAGACTTTATTGATGCTTACCT TAAAGAAATGTCAAAGCACACAGGCAATCCTACTTCAAGTTTCCATGAAGAAAACCTCAT CTGCAGCACCCTGGACCTCTTCTTTGCCGGAACCGAGACAACTTCCACAACTCTGCGATG GGCTCTGCTTTATATGGCCCTCTACCCAGAAATCCAAGAAAAAGTACAAGCTGAGATTGA CAGAGTGATTGGCCAGGGGCAGCAGCCGAGCACAGCCGCCCGGGAGTCCATGCCCTACAC CAATGCTGTCATCCATGAGGTGCAGAGAATGGGCAACATCATCCCCCTGAACGTTCCCAG GGAAGTGACAGTTGATACCACTTTGGCTGGGTACCACCTGCCCAAGGGTACCATGATCCT GACCAATTTGACGGCGCTGCACAGGGACCCCACAGAGTGGGCCACCCCTGACACATTCAA TCCGGACCATTTTCTGGAGAATGGACAGTTTAAGAAAAGGGAAGCCTTTATGCCTTTCTC AATAGGAAAGCGGGCATGCCTCGGAGAACAGTTGGCCAGGACTGAGCTGTTTATTTTCTT CACTTCCCTTATGCAAAAATTTACCTTCAGGCCCCCAAACAATGAGAAGCTGAGCCTGAA GTTTAGAATGGGTATCACCATTTCCCCAGTCAGTCACCGCCTCTGCGCTGTTCCTCAGGT GTAATATTGTTAAGAAAGAAAGGGGCAAGGAAAGTAAGAAGACATGGCACGTGTTCTGAA ACCACTGGTGTCTGCTCAGATGTGTTGGGACAAAATGAAAGTGACTTTCAAGAAAGATCA GAGGAATTTGACTCAGAGAAAACTAGATCCAAATCCCAGCTCTACTGTCTCGTCCGAATT AGCCTTGGGAAAATCATTTATATGCTAAATAATTTACCTTTTTATCTAGGAGATGAAAAG AGGATAATGTTTCCTTCCATAAAGAAAGTTCTTGTAAGAATCAAAAGAAATGGTGAGCTT TAAGTGGTTTGTAAACCATAAAACACATCATAAAAGTTCTATCTATAAAAAAAAAAAAAA AAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_000775 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000775.2, NP_000766.2 |
| RefSeq Size | 1876 bp |
| RefSeq ORF | 1509 bp |
| Locus ID | 1573 |
| UniProt ID | P51589 |
| Domains | p450 |
| Protein Families | Druggable Genome, P450, Transmembrane |
| Protein Pathways | Arachidonic acid metabolism, Linoleic acid metabolism, Metabolic pathways |
| Gene Summary | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is thought to be the predominant enzyme responsible for epoxidation of endogenous arachidonic acid in cardiac tissue. Multiple transcript variants have been found for this gene. [provided by RefSeq, Jan 2016] Transcript Variant: This variant (1) is the protein-coding transcript. |
Citations (7)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Anthracycline derivatives inhibit cardiac CYP2J2.
,null,
Journal of inorganic biochemistry
,PubMed ID 35078036
[CYP2J2]
|
|
Lipid composition and macromolecular crowding effects on CYP2J2-mediated drug metabolism in nanodiscs
,Huff, HC;Maroutsos, D;Das, A;,
Protein Sci.
,PubMed ID 30861250
[CYP2J2]
|
|
Asymmetric binding and metabolism of polyunsaturated fatty acids (PUFAs) by CYP2J2 epoxygenase
,Arnold, WR;Baylon, JL;Tajkhorshid, E;Das, A;,
Biochemistry
,PubMed ID 27992998
[CYP2J2]
|
|
Substrate binding to cytochrome P450-2J2 in Nanodiscs detected by nanoplasmonic Lycurgus cup arrays.
,null,
Biosensors & bioelectronics
,PubMed ID 26334592
[CYP2J2]
|
|
Early Changes in Cytochrome P450s and Their Associated Arachidonic Acid Metabolites Play a Crucial Role in the Initiation of Cardiac Hypertrophy Induced by Isoproterenol
,Althurwi, HN;Maayah, ZH;Elshenawy, OH;El-Kadi, AO;,
Drug Metab. Dispos.
,PubMed ID 26033621
[CYP2J2]
|
|
Substrate binding to cytochrome P450-2J2 in Nanodiscs detected by nanoplasmonic Lycurgus cup Arrays
,Plucinski, L;Gartia, MR;Arnold, WR;Ameen, A;,
Biosensors and Bioelectronics
[CYP2J2]
|
|
Functional studies of N-terminally modified CYP2J2 epoxygenase in model lipid bilayers
,null,
Protein Science : A Publication of the Protein Society
,PubMed ID 23661295
[CYP2J2]
|
Documents
| Product Manuals |
| FAQs |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207417 | CYP2J2 (Myc-DDK-tagged)-Human cytochrome P450, family 2, subfamily J, polypeptide 2 (CYP2J2) |
CNY 3,736.00 |
|
| RC207417L3 | Lenti ORF clone of Human cytochrome P450, family 2, subfamily J, polypeptide 2 (CYP2J2), Myc-DDK-tagged |
CNY 6,270.00 |
|
| RC207417L4 | Lenti ORF clone of Human cytochrome P450, family 2, subfamily J, polypeptide 2 (CYP2J2), mGFP tagged |
CNY 6,270.00 |
|
| RG207417 | CYP2J2 (tGFP-tagged) - Human cytochrome P450, family 2, subfamily J, polypeptide 2 (CYP2J2) |
CNY 5,336.00 |
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