United States
Germany
Japan
United Kingdom
China
DRP1 (DNM1L) (NM_012063) Human Untagged Clone
CAT＃: SC321766
DNM1L (untagged)-Human dynamin 1-like (DNM1L), transcript variant 2
CNY 5,208.00
Product images
CNY 1,999.00
CNY 2,700.00
热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DLP1; DRP1; DVLP; DYMPLE; EMPF; EMPF1; HDYNIV; OPA5 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_012063.1
CCGGCGGGCACTGGGGCCCCGTGTTTTCAGAGTCATGGAGGCGCTAATTCCTGTCATAAA
CAAGCTCCAGGACGTCTTCAACACGGTGGGCGCCGACATCATCCAGCTGCCTCAAATCGT CGTAGTGGGAACGCAGAGCAGCGGAAAGAGCTCAGTGCTAGAAAGCCTGGTGGGGAGGGA CCTGCTTCCCAGAGGTACTGGAATTGTCACCCGGAGACCTCTCATTCTGCAACTGGTCCA TGTTTCACAAGAAGATAAACGGAAAACAACAGGAGAAGAAAATGGGGTGGAAGCAGAAGA ATGGGGTAAATTTCTTCACACCAAAAATAAGCTTTACACGGATTTTGATGAAATTCGACA AGAAATTGAAAATGAAACAGAAAGAATTTCAGGAAATAATAAGGGAGTAAGCCCTGAACC AATTCATCTTAAGATTTTTTCACCCAACGTTGTCAATTTGACACTTGTGGATTTGCCAGG AATGACCAAGGTGCCTGTAGGTGATCAACCTAAGGATATTGAGCTTCAAATCAGAGAGCT CATTCTTCGGTTCATCAGTAATCCTAATTCCATTATCCTCGCTGTCACTGCTGCTAATAC AGATATGGCAACATCAGAGGCACTTAAAATTTCAAGAGAGGTAGATCCAGATGGTCGCAG AACCCTAGCTGTAATCACTAAACTTGATCTCATGGATGCGGGTACTGATGCCATGGATGT ATTGATGGGAAGGGTTATTCCAGTCAAACTTGGAATAATTGGAGTAGTTAACAGGAGCCA GCTAGATATTAACAACAAGAAGAGTGTAACTGATTCAATCCGTGATGAGTATGCTTTTCT TCAAAAGAAATATCCATCTCTGGCCAATAGAAATGGAACAAAGTATCTTGCTAGGACTCT AAACAGGTTACTGATGCATCACATCAGAGATTGTTTACCAGAGTTGAAAACAAGAATAAA TGTTCTAGCTGCTCAGTATCAGTCTCTTCTAAATAGCTACGGTGAACCCGTGGATGATAA AAGTGCTACTTTACTCCAACTTATTACCAAATTTGCCACAGAATATTGTAACACTATTGA AGGAACTGCAAAATATATTGAAACTTCGGAGCTATGCGGTGGTGCTAGAATTTGTTATAT TTTCCATGAGACTTTTGGGCGAACCTTAGAATCTGTTGATCCACTTGGTGGCCTTAACAC TATTGACATTTTGACTGCCATTAGAAATGCTACTGGTCCTCGTCCTGCTTTATTTGTGCC TGAGGTTTCATTTGAGTTACTGGTGAAGCGGCAAATCAAACGTCTAGAAGAGCCCAGCCT CCGCTGTGTGGAACTGGTTCATGAGGAAATGCAAAGGATCATTCAGCACTGTAGCAATTA CAGTACACAGGAATTGTTACGATTTCCTAAACTTCATGATGCCATAGTTGAAGTGGTGAC TTGTCTTCTTCGTAAAAGGTTGCCTGTTACAAATGAAATGGTCCATAACTTAGTGGCAAT TGAACTGGCTTATATCAACACAAAACATCCAGACTTTGCTGATGCTTGTGGGCTAATGAA CAATAATATAGAGGAACAAAGGAGAAACAGGCTAGCCAGAGAATTACCTTCAGCTGTATC ACGAGACAAGTTAATTCAGGACAGCAGAAGAGAAACTAAAAATGTTGCATCTGGAGGTGG TGGGGTTGGAGATGGTGTTCAAGAACCAACCACAGGCAACTGGAGAGGAATGCTGAAAAC TTCAAAAGCTGAAGAGTTATTAGCAGAAGAAAAATCAAAACCCATTCCAATTATGCCAGC CAGTCCACAAAAAGGTCATGCCGTGAACCTGCTAGATGTGCCAGTTCCTGTTGCACGAAA ACTATCTGCTCGGGAACAGCGAGATTGTGAGGTTATTGAACGACTCATTAAATCATATTT TCTCATTGTCAGAAAGAATATTCAAGACAGTGTGCCAAAGGCAGTAATGCATTTTTTGGT TAATCATGTGAAAGACACTCTTCAGAGTGAGCTAGTAGGCCAGCTGTATAAATCATCCTT ATTGGATGATCTTCTGACAGAATCTGAGGACATGGCACAGCGCAGGAAAGAAGCAGCTGA TATGCTAAAGGCATTACAAGGAGCCAGTCAAATTATTGCTGAAATCCGGGAGACTCATCT TTGGTGAAGAGAACTATGTAATACTGAGACTTTGTTGACTCAAAACTTGCTAGTTACTGC CTACCTGAGTAGAATCTTATTTATGAACTCCTGTGTATTGCAATGGTATGAATCTGCTCA TGTGGAGACTGGCTATAAACTGAAAAGTGTATTCCAAATTGCAGAACACATCACACATTT AATCCAAATAATAAATGGCTGTTTCTAAAGTTTCCCAGTAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_012063 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_012063.1, NP_036193.1 |
| RefSeq Size | 2415 bp |
| RefSeq ORF | 2133 bp |
| Locus ID | 10059 |
| UniProt ID | O00429 |
| Domains | dynamin_2, dynamin, GED |
| Protein Pathways | Endocytosis, Fc gamma R-mediated phagocytosis |
| Gene Summary | This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013] Transcript Variant: This variant (2) lacks an in-frame exon in the 3' coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202046 | DNM1L (Myc-DDK-tagged)-Human dynamin 1-like (DNM1L), transcript variant 2 |
CNY 5,200.00 |
|
| RC202046L1 | Lenti ORF clone of Human dynamin 1-like (DNM1L), transcript variant 2, Myc-DDK-tagged |
CNY 7,600.00 |
|
| RC202046L2 | Lenti ORF clone of Human dynamin 1-like (DNM1L), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC202046L3 | Lenti ORF clone of Human dynamin 1-like (DNM1L), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC202046L4 | Lenti ORF clone of Human dynamin 1-like (DNM1L), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG202046 | DNM1L (tGFP-tagged) - Human dynamin 1-like (DNM1L), transcript variant 2 |
CNY 6,800.00 |
