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FPRL1 (FPR2) (NM_001005738) Human Untagged Clone
CAT＃: SC321988
FPR2 (untagged)-Human formyl peptide receptor 2 (FPR2), transcript variant 2
CNY 5,488.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ALXR; FMLP-R-II; FMLPX; FPR2A; FPRH1; FPRH2; FPRL1; HM63; LXA4R |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for SC321988
GAAGGAAGGGCTGGACATTCAGATTCCTTGACCCTTGACATTTGGAAGCATGAACTCCAG
TCTCTCACAGAAGGCTAGAGGTGAAGGAACATTCAGACACATTGGTTTCTAAGAAGAGTC CGCTGACAACATACCCAAGGTGTCTTCTGAAAATTATAAGAAATCCTGAGTTTCTGTTAG GGGATTGGCTCCAGCTCCATTGTCCCTCCCCCATCATTCAGTAGTCTCCGCGAAAGCCCT TAGAGCCGGTGTTGCTCCACAGGAAGCCAAGAAGCACACAGGAAAAGGAGCTTAGCTGCT GGTGCTGCTGGCAAGATGGAAACCAACTTCTCCACTCCTCTGAATGAATATGAAGAAGTG TCCTATGAGTCTGCTGGCTACACTGTTCTGCGGATCCTCCCATTGGTGGTGCTTGGGGTC ACCTTTGTCCTCGGGGTCCTGGGCAATGGGCTTGTGATCTGGGTGGCTGGATTCCGGATG ACACGCACAGTCACCACCATCTGTTACCTGAACCTGGCCCTGGCTGACTTTTCTTTCACG GCCACATTACCATTCCTCATTGTCTCCATGGCCATGGGAGAAAAATGGCCTTTTGGCTGG TTCCTGTGTAAGTTAATTCACATCGTGGTGGACATCAACCTCTTTGGAAGTGTCTTCTTG ATTGGTTTCATTGCACTGGACCGCTGCATTTGTGTCCTGCATCCAGTCTGGGCCCAGAAC CACCGCACTGTGAGTCTGGCCATGAAGGTGATCGTCGGACCTTGGATTCTTGCTCTAGTC CTTACCTTGCCAGTTTTCCTCTTTTTGACTACAGTAACTATTCCAAATGGGGACACATAC TGTACTTTCAACTTTGCATCCTGGGGTGGCACCCCTGAGGAGAGGCTGAAGGTGGCCATT ACCATGCTGACAGCCAGAGGGATTATCCGGTTTGTCATTGGCTTTAGCTTGCCGATGTCC ATTGTTGCCATCTGCTATGGGCTCATTGCAGCCAAGATCCACAAAAAGGGCATGATTAAA TCCAGCCGTCCCTTACGGGTCCTCACTGCTGTGGTGGCTTCTTTCTTCATCTGTTGGTTT CCCTTTCAACTGGTTGCCCTTCTGGGCACCGTCTGGCTCAAAGAGATGTTGTTCTATGGC AAGTACAAAATCATTGACATCCTGGTTAACCCAACGAGCTCCCTGGCCTTCTTCAACAGC TGCCTCAACCCCATGCTTTACGTCTTTGTGGGCCAAGACTTCCGAGAGAGACTGATCCAC TCCCTGCCCACCAGTCTGGAGAGGGCCCTGTCTGAGGACTCAGCCCCAACTAATGACACG GCTGCCAATTCTGCTTCACCTCCTGCAGAGACTGAGTTACAGGCAATGTGAGGATGGGGT CAGGGATATTTTGAGTTCTGTTCATCCTACCCTAATGCCAGTTCCAGCTTCATCTACCCT TGAGTCATATTGAGGCATTCAAGGATGCACAGCTCAAGTATTTATTCAGGAAAAATGCTT TTGTGTCCCTGATTTGGGGCTAAGAAATAGACAGTCAGGCTACTAAAATATTAGTGTTAT TTTTTGTTTTTTGACTTCTGCCTATACCCTGGGGTAAGTGGAGTTGGGAAATACAAGAAG AGAAAGACCAGTGGGGATTTGTAAGACTTAGATGAGATAGCGCATAATAAGGGGAAGACT TTAAAGTATAAAGTAAAATGTTTGCTGTAGGTTTTTTATAGCTATTAAAAAAAATCAGAT TATGGAAGTTTTCTTCTATTTTTAGTTTGCTAAGAGTTTTCTGTTTCTTTTTCTTACATC ATGAGTGGACTTTGCATTTTATCAAATGCATTTTCTACATGTATTAAGATGGTCATATTA TTCTTCTTCTTTTATGTAAATCATTATAAATAATGTTCATTAAGTTCTGAATGTTAAACT ACTCTTGAATTCCTGGAATAAACCACACTTAGTCCTGATGTACTTTAAATATTTATATCT CACAGGAGTTGGTTAGAATTTCTGTGTTTATGTTTATATACTGTTATTTCACTTTTTCTA CTATCCTTGCTAAGTTTTCATAGAAAATAAGGAACAAAGAGAAACTTGTAATGGTCTCTG AAAAGGAATTGAGAAGTAATTCCTCTGATTCTGTTTTCTGGTGTTATATCTTTATTAAAT ATTCAGAAAAATTCAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_001005738 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001005738.1, NP_001005738.1 |
| RefSeq Size | 1921 bp |
| RefSeq ORF | 1056 bp |
| Locus ID | 2358 |
| UniProt ID | P25090 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Neuroactive ligand-receptor interaction |
| Gene Summary | Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophil chemotactic factors (PubMed:1374236). Binding of FMLP to the receptor causes activation of neutrophils (PubMed:1374236). This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (PubMed:1374236). The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4) (PubMed:9547339). Receptor for the chemokine-like protein FAM19A5, mediating FAM19A5-stimulated macrophage chemotaxis and the inhibitory effect on TNFSF11/RANKL-induced osteoclast differentiation (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209953 | FPR2 (Myc-DDK-tagged)-Human formyl peptide receptor 2 (FPR2), transcript variant 2 |
CNY 5,856.00 |
|
| RC209953L3 | Lenti-ORF clone of FPR2 (Myc-DDK-tagged)-Human formyl peptide receptor 2 (FPR2), transcript variant 2 |
CNY 5,890.00 |
|
| RC209953L4 | Lenti-ORF clone of FPR2 (mGFP-tagged)-Human formyl peptide receptor 2 (FPR2), transcript variant 2 |
CNY 5,890.00 |
|
| RG209953 | FPR2 (tGFP-tagged) - Human formyl peptide receptor 2 (FPR2), transcript variant 2 |
CNY 7,456.00 |
