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L Kynurenine Hydrolase (KYNU) (NM_001032998) Human Untagged Clone
CAT＃: SC322236
KYNU (untagged)-Human kynureninase (KYNU), transcript variant 2
CNY 2,400.00
CNY 6,270.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | KYNUU; VCRL2 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for SC322236
GGCCTGTACATTTTCAAGGAATTCTTGAGAGGTTCTTGGAGAGATTCTGGGAGCCAAACA
CTCCATTGGGATCCTAGCTGTTTTAGAGAACAACTTGTAATGGAGCCTTCATCTCTTGAG CTGCCGGCTGACACAGTGCAGCGCATTGCGGCTGAACTCAAATGCCACCCAACGGATGAG AGGGTGGCTCTCCACCTAGATGAGGAAGATAAGCTGAGGCACTTCAGGGAGTGCTTTTAT ATTCCCAAAATACAGGATCTGCCTCCAGTTGATTTATCATTAGTGAATAAAGATGAAAAT GCCATCTATTTCTTGGGAAATTCTCTTGGCCTTCAACCAAAAATGGTTAAAACATATCTT GAAGAAGAACTAGATAAGTGGGCCAAAATAGCAGCCTATGGTCATGAAGTGGGGAAGCGT CCTTGGATTACAGGAGATGAGAGTATTGTAGGCCTTATGAAGGACATTGTAGGAGCCAAT GAGAAAGAAATAGCCCTAATGAATGCTTTGACTGTAAATTTACATCTTCTAATGTTATCA TTTTTTAAGCCTACGCCAAAACGATATAAAATTCTTCTAGAAGCCAAAGCCTTCCCTTCT GATCATTATGCTATTGAGTCACAACTACAACTTCACGGACTTAACATTGAAGAAAGTATG CGGATGATAAAGCCAAGAGAGGGGGAAGAAACCTTAAGAATAGAGGATATCCTTGAAGTA ATTGAGAAGGAAGGAGACTCAATTGCAGTGATCCTGTTCAGTGGGGTGCATTTTTACACT GGACAGCACTTTAATATTCCTGCCATCACAAAAGCTGGACAAGCGAAGGGTTGTTATGTT GGCTTTGATCTAGCACATGCAGTTGGAAATGTTGAACTCTACTTACATGACTGGGGAGTT GATTTTGCCTGCTGGTGTTCCTACAAGTATTTAAATGCAGGAGCAGGAGGAATTGCTGGT GCCTTCATTCATGAAAAGCATGCCCATACGATTAAACCTGCGAGATCGGAGTTCTTTAAT TAGGAATGGAATGCAACAGATTTGGACAAGTCAAGGACAAGAGCTTTAGAGAGACCAAAG AGTTTTTCACTGTTAAAGTGTCCAGTATGTAGCCGAGAACCATATGGAGAACATCAAATA CAGTGGAACAAATGTAACTGCTATTGATGTCACACTTTGTGAAGTAGTCTTTGTTGCTTA AAAAGGGTGACATCTAGTGGCTAAACATGTTATTTCAAATAAATAATATCGAAATAAAAA AAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_001032998 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001032998.1, NP_001028170.1 |
| RefSeq Size | 1315 bp |
| RefSeq ORF | 924 bp |
| Locus ID | 8942 |
| UniProt ID | Q16719 |
| Protein Families | Protease |
| Protein Pathways | Metabolic pathways, Tryptophan metabolism |
| Gene Summary | Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010] Transcript Variant: This variant (2) differs in the 5' UTR, 3' UTR and coding region compared to variant 3. The resulting isoform (b) is shorter and has a distinct C-terminus compared to isoform a. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201559 | KYNU (Myc-DDK-tagged)-Human kynureninase (KYNU), transcript variant 2 |
CNY 3,600.00 |
|
| RC201559L1 | Lenti ORF clone of Human kynureninase (KYNU), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC201559L2 | Lenti ORF clone of Human kynureninase (KYNU), transcript variant 2, mGFP tagged |
CNY 6,000.00 |
|
| RC201559L3 | Lenti ORF clone of Human kynureninase (KYNU), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC201559L4 | Lenti ORF clone of Human kynureninase (KYNU), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG201559 | KYNU (tGFP-tagged) - Human kynureninase (KYNU), transcript variant 2 |
CNY 5,200.00 |
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