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INPP5E (NM_019892) Human Untagged Clone
CAT＃: SC323870
INPP5E (untagged)-Human inositol polyphosphate-5-phosphatase, 72 kDa (INPP5E)
CNY 4,800.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CORS1; CPD4; JBTS1; MORMS; pharbin; PPI5PIV |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_019892.3
CTGGGCGGCCGGGCCTCCGCGAGTACCGGGTCGACTTCGGAGTCTGCGAGCCCAGCCAGG
GGTGCCCGCTTCCCACCCCTCTCCCCGAGCGGCGTCCCCGTCGGGGTCGAACCTCCCCCG CGACAGGCGCCCAGCCGCCTGTTCCCCCAGGCCTTGCCTGCGGACCGCCCTGGGAACGGC GTCTGGGAGCCCCGAGGGGCTGGCGGGACTCGGGGCCCGGGCCATGCGGCAGCCGCCCCC GCCCCTCCGCGACCATCCCCGGCCCAAGCGGGAGCCGCAGCGGCGTTTCTGCTCCTCGCT GCGCCGGCGACCCCGGACCCGGCACCCGTGACCCCTCGCGCTGCCTGCGGCCTCGCGCCG AGGCCTGCCCCGGGAGAGACCGTCCATGCCGTCCAAGGCGGAGAATCTGCGGCCCTCCGA GCCGGCCCCGCAGCCGCCGGAAGGGAGGACGCTCCAAGGACAGCTTCCCGGCGCTCCGCC GGCCCAGCGCGCGGGGTCCCCACCCGATGCTCCGGGCTCCGAGAGCCCCGCGCTTGCCTG CAGCACTCCGGCCACGCCCAGCGGCGAGGACCCGCCAGCCCGAGCAGCACCCATCGCCCC GCGGCCCCCCGCCAGGCCTCGACTGGAGCGAGCCCTGTCCCTGGACGACAAGGGCTGGAG GAGGAGGCGTTTTCGAGGCAGCCAGGAGGACCTGGAAGCCCGGAATGGGACCAGTCCCTC CAGGGGCTCAGTGCAGAGCGAGGGCCCCGGGGCCCCCGCCCACAGCTGCTCCCCGCCCTG CCTGAGCACCTCCTTGCAGGAAATCCCCAAGTCCCGCGGGGTCCTGAGCAGTGAGAGAGG GAGCCCGTCCTCGGGGGGTAACCCTCTCTCTGGGGTGGCCAGCAGCTCCCCGAACCTCCC GCACAGAGACGCCGCCGTGGCGGGGAGCTCGCCCAGGCTGCCCAGCCTGCTGCCCCCGCG CCCACCGCCTGCCCTGAGCCTGGACATCGCCTCCGACTCCCTGAGGACAGCAAACAAGGT CGACTCGGATCTTGCAGACTACAAGCTCCGCGCGCAGCCGCTCCTGGTGCGGGCCCACAG CAGCCTGGGCCCCGGCCGGCCGCGGAGCCCCCTGGCCTGCGACGACTGTTCCCTTCGCTC GGCCAAATCCTCCTTCAGCCTCCTGGCGCCCATCCGCAGCAAGGACGTCCGCAGCAGGAG TTACCTGGAGGGCAGCCTCCTGGCCAGCGGGGCCCTGTTGGGGGCGGATGAGCTGGCCCG CTACTTCCCAGACCGGAACGTGGCACTCTTCGTGGCCACCTGGAACATGCAGGGCCAGAA GGAGCTCCCGCCCAGCCTGGACGAGTTCCTGCTCCCAGCCGAGGCCGACTATGCCCAGGA CCTGTATGTCATCGGGGTCCAGGAGGGCTGTTCTGACAGGCGGGAGTGGGAGACTCGTCT GCAGGAGACGCTGGGCCCGCACTATGTGCTGCTGTCCTCGGCGGCCCACGGCGTGCTCTA CATGTCGCTCTTCATCCGCAGGGACCTCATCTGGTTCTGCTCAGAGGTGGAGTGCTCCAC GGTGACCACACGCATCGTGTCTCAGATCAAGACCAAGGGGGCCTTGGGCATCAGCTTCAC CTTTTTTGGCACTTCCTTCCTCTTCATCACGTCCCACTTCACCTCAGGTGACGGGAAGGT GGCGGAGCGGCTGCTGGACTACACCAGGACTGTACAAGCCCTGGTCCTGCCCAGAAATGT GCCCGACACCAACCCCTATCGCTCCAGCGCAGCGGACGTCACCACCCGCTTCGATGAGGT GTTCTGGTTTGGAGACTTCAACTTCCGCCTGAGTGGCGGGCGCACAGTCGTGGACGCCCT CCTGTGCCAGGGCCTGGTGGTGGACGTGCCGGCGCTGCTGCAGCACGACCAGCTCATCCG GGAGATGCGGAAAGGGTCCATCTTCAAGGGCTTCCAGGAGCCGGACATCCACTTCCTCCC ATCATACAAGTTTGACATCGGGAAGGACACGTACGACAGCACCTCCAAGCAGAGGACGCC CTCATACACGGACCGCGTCTTGTACAGAAGCCGCCACAAGGGTGACATCTGTCCTGTGAG CTACTCTTCCTGCCCCGGGATCAAGACGTCCGACCACCGCCCTGTGTATGGCCTCTTCCG GGTGAAAGTGAGGCCGGGGCGAGACAACATTCCGTTGGCAGCTGGCAAATTTGATAGAGA ACTGTACTTACTAGGAATTAAAAGACGGATTTCGAAGGAGATTCAGAGGCAGCAAGCACT ACAGAGTCAGAACTCCAGCACCATCTGCTCCGTTTCTTGAAGTTTGCTGAACGAGGACTC ACAGCTGCAACGTGGGGTGATTGTATTGATCAAAACCCACTGGGAAGGACAAAGAGTTTG CCGCCTTTCGGGGATCCGAGGGACTGTGGCGACCGTGCCTCTGTGCCAGCGTCCCAGGAA GGAAGCCAACCCTGAGCGAGCCTGTCCTCTGTGGCAGGTCCACACGGTGTGGGTGGGCAG GGCTTGGACCCCCGTCTCCATGGCAGGTCCATACAGCATGGGTGGCAGGGTTTGGACCCG CCCAGCAGCACCACGGACCCCAGCCACTCTCGGGGGCAGACGTCAGAATCCGTTCCTGAG CAGCTCCTGTGCCCTGGGGGCAGTCACAGAGCCCCCCAACACCCCCGTGCTCTGCACCAG CCTCTCCCTCCACACCCGAAGCAGGCGTCCATCTGTGTCCTCCTGGCAGCCCCTCAAACA CACACCACCCCATGTCACACGGGTATCCAGAGCAAGGCTGGATCTGGGCTAGGTGACCCC TGGGGCCTCAGACCTCTGAGTGGGCCCCAGAGCCCAGCTGAGGAAGCCACACAGCCTCCA GGACGTGGCACGGTTCCCCTCCACTTGGCTGCAAGTCGCCTGCCATGGGGCGAGGAGGCC TGCACCCCAGTATAAGGGCCTCCCCAGCTGAGTAAGAAGCTGCTTCCCCTCCTCTCATAG GCCAAGCCTATTGTGTGAAACCATCTCATGGTCTTGGTGACGTAGACCATTTTTGAAACC GTCTCATGGTCTTGGTGACGTAGACCGTTTGCTTCTTTAACTCCAGCCGCGGAATGACAT TAGTGGAACCGGGCTAGGGAACTGCTGGAAGTTCAGGATGCCACCACCTTGAACACCTAG GCCAGGGATCCCCACCATGTCCCGGGTTTCTTTCTTCGAGAGTATAGAACCGTTCATTCT TGCTTTGTGTCCCATTCCATCTCTTGAAAAAATGTAGTCTTTGAATGTGTGAAAATCTAG GGACATTCAATCTAGTCTTTTAAATTATTTTTCCATATTTATATTTTTAAATAAATGCAT ATATTGAGTCTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | ECoRI-NOT |
| ACCN | NM_019892 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_019892.3, NP_063945.2 |
| RefSeq Size | 3440 bp |
| RefSeq ORF | 1935 bp |
| Locus ID | 56623 |
| UniProt ID | Q9NRR6 |
| Protein Families | Druggable Genome |
| Protein Pathways | Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system |
| Gene Summary | The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. Studies of the mouse counterpart suggest that this protein may hydrolyze phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,5-bisphosphate on the cytoplasmic Golgi membrane and thereby regulate Golgi-vesicular trafficking. Mutations in this gene cause Joubert syndrome; a clinically and genetically heterogenous group of disorders characterized by midbrain-hindbrain malformation and various associated ciliopathies that include retinal dystrophy, nephronophthisis, liver fibrosis and polydactyly. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206984 | INPP5E (Myc-DDK-tagged)-Human inositol polyphosphate-5-phosphatase, 72 kDa (INPP5E) |
CNY 4,792.00 |
|
| RC206984L1 | Lenti ORF clone of Human inositol polyphosphate-5-phosphatase, 72 kDa (INPP5E), Myc-DDK-tagged |
CNY 7,192.00 |
|
| RC206984L2 | Lenti ORF clone of Human inositol polyphosphate-5-phosphatase, 72 kDa (INPP5E), mGFP tagged |
CNY 5,890.00 |
|
| RC206984L3 | Lenti ORF clone of Human inositol polyphosphate-5-phosphatase, 72 kDa (INPP5E), Myc-DDK-tagged |
CNY 7,192.00 |
|
| RC206984L4 | Lenti ORF clone of Human inositol polyphosphate-5-phosphatase, 72 kDa (INPP5E), mGFP tagged |
CNY 7,192.00 |
|
| RG206984 | INPP5E (tGFP-tagged) - Human inositol polyphosphate-5-phosphatase, 72 kDa (INPP5E) |
CNY 6,392.00 |
