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CTCF (NM_006565) Human Untagged Clone
CAT＃: SC324590
CTCF (untagged)-Human CCCTC-binding factor (zinc finger protein) (CTCF), transcript variant 1
CNY 5,336.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CFAP108; FAP108; MRD21 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_006565.2
GTGGAGCGATTAAACCGTGCGCGGAGCTGCTTCTTTGGCGGCAGCGGCGGCGGCGGTGGC
CGGTGCGGACGCGCGGAGCTCGCCGGAGACGCCGGGTGGCCGGAGCCGTGGAGCGGCGGC GGAGCGGGCGCCGCGGGGGGTGTGGCGCGGAGAATGATTACGGACCTGAAGCCAAAGAAC AAGATGCGCTAGTGGACAGATTGCTGACCAGGGGCTTGAGAGCTGGGTTCTATTTTCCCT CCTCAAACTGACTTTGCAGCCACGGAGAGGCAGGGGAAATGGAAGGTGATGCAGTCGAAG CCATTGTGGAGGAGTCCGAAACTTTTATTAAAGGAAAGGAGAGAAAGACTTACCAGAGAC GCCGGGAAGGGGGCCAGGAAGAAGATGCCTGCCACTTACCCCAGAACCAGACGGATGGGG GTGAGGTGGTCCAGGATGTCAACAGCAGTGTACAGATGGTGATGATGGAACAGCTGGACC CCACCCTTCTTCAGATGAAGACTGAAGTAATGGAGGGCACAGTGGCTCCAGAAGCAGAGG CTGCTGTGGACGATACCCAGATTATAACTTTACAGGTTGTAAATATGGAGGAACAGCCCA TAAACATAGGAGAACTTCAGCTTGTTCAAGTACCTGTTCCTGTGACTGTACCTGTTGCTA CCACTTCAGTAGAAGAACTTCAGGGGGCTTATGAAAATGAAGTGTCTAAAGAGGGCCTTG CGGAAAGTGAACCCATGATATGCCACACCCTACCTTTGCCTGAAGGGTTTCAGGTGGTTA AAGTGGGGGCCAATGGAGAGGTGGAGACACTAGAACAAGGGGAACTTCCACCCCAGGAAG ATCCTAGTTGGCAAAAAGACCCAGACTATCAGCCACCAGCCAAAAAAACAAAGAAAACCA AAAAGAGCAAACTGCGTTATACAGAGGAGGGCAAAGATGTAGATGTGTCTGTCTACGATT TTGAGGAAGAACAGCAGGAGGGTCTGCTATCAGAGGTTAATGCAGAGAAAGTGGTTGGTA ATATGAAGCCTCCAAAGCCAACAAAAATTAAAAAGAAAGGTGTAAAGAAGACATTCCAGT GTGAGCTTTGCAGTTACACGTGTCCACGGCGTTCAAATTTGGATCGTCACATGAAAAGCC ACACTGATGAGAGACCACACAAGTGCCATCTCTGTGGCAGGGCATTCAGAACAGTCACCC TCCTGAGGAATCACCTTAACACACACACAGGTACTCGTCCTCACAAGTGCCCAGACTGCG ACATGGCCTTTGTGACCAGTGGAGAATTGGTTCGGCATCGTCGTTACAAACACACCCACG AGAAGCCATTCAAGTGTTCCATGTGCGATTACGCCAGTGTAGAAGTCAGCAAATTAAAAC GTCACATTCGCTCTCATACTGGAGAGCGTCCGTTTCAGTGCAGTTTGTGCAGTTATGCCA GCAGGGACACATACAAGCTGAAAAGGCACATGAGAACCCATTCAGGGGAAAAGCCTTATG AATGTTATATTTGTCATGCTCGGTTTACCCAAAGTGGTACCATGAAGATGCACATTTTAC AGAAGCACACAGAAAATGTGGCCAAATTTCACTGTCCCCACTGTGACACAGTCATAGCCC GAAAAAGTGATTTGGGTGTCCACTTGCGAAAGCAGCATTCCTATATTGAGCAAGGCAAGA AATGCCGTTACTGTGATGCTGTGTTTCATGAGCGCTATGCCCTCATCCAGCATCAGAAGT CACACAAGAATGAGAAGCGCTTTAAGTGTGACCAGTGTGATTACGCTTGTAGACAGGAGA GGCACATGATCATGCACAAGCGCACCCACACCGGGGAGAAGCCTTACGCCTGCAGCCACT GCGATAAGACCTTCCGCCAGAAGCAGCTTCTCGACATGCACTTCAAGCGCTATCACGACC CCAACTTCGTCCCTGCGGCTTTTGTCTGTTCTAAGTGTGGGAAAACATTTACACGTCGGA ATACCATGGCAAGACATGCTGATAATTGTGCTGGCCCAGATGGCGTAGAGGGGGAAAATG GAGGAGAAACGAAGAAGAGTAAACGTGGAAGAAAAAGAAAGATGCGCTCTAAGAAAGAAG ATTCCTCTGACAGTGAAAATGCTGAACCAGATCTGGACGACAATGAGGATGAGGAGGAGC CTGCCGTAGAAATTGAACCTGAGCCAGAGCCTCAGCCTGTGACCCCAGCCCCACCACCCG CCAAGAAGCGGAGAGGACGACCCCCTGGCAGAACCAACCAGCCCAAACAGAACCAGCCAA CAGCTATCATTCAGGTTGAAGACCAGAATACAGGTGCAATTGAGAACATTATAGTTGAAG TAAAAAAAGAGCCAGATGCTGAGCCCGCAGAGGGAGAGGAAGAGGAGGCCCAGCCAGCTG CCACAGATGCCCCCAACGGAGACCTCACGCCCGAGATGATCCTCAGCATGATGGACCGGT GATGGCGGAGCCTTGTGCGTCGCCAGGACTTCTCTGGGCTGTGTTTAAACGGCCCGCATC TTAATTTTTCTCCCTTCTTTCTTTTTTTGGCTTTGGGAAAAGCATCATTTTACCAAACAT ACCGAGAACGAAAACTTCAAGGATGATGTTAGAAAAAAATGTGATTTAACTAGAACTTGC TGTCTGATGTTAGCAAATCATGGAATGTTCTGAGTCCCTGAGGGTTTACTGTGAAGTGCT GAGGACAGTGTTGACAACTAACTCGTTTTCCTAGATGGAAACGGAGACATTGACCCCTCC CTCCATGTGGTAAACCACTCCAGAATGGCCACCAGGCTTCCCAGAGTTCTATGGTCTTCT TCCCAAGAGAGTTTTTAATTGTAAATGCATACTTGGGAAGGACTTAGAGTTTTAAACTGT TTTTTGCTTTTGCTTTTCCCTGACTCCCTTTGCTTGGAGTCAGCTGCACACCAGTAGTAT GGCATGCTACGATCAGGTTCTGTCCTGAAAGCTTTGCCTCTTTCTTGGCAAAGTTTCTGG TATGGTCAAGCTTGTAAATAACTTTTTTTACATTTTAATCTTTTCCATTAATTAAGAGGT TGAAAAGAAGTGCAGTGTAAGAAAACCCAGCATTTTAATTACTTGCAAATTAAGTTACCA CAGACTCTGTAGTGTGTAAATGTTGACAAGGAATTGGATCACAATCATGTAGCAGAATGG CACCCAGACCACTGCCCACCAGTGACGGACATGCACGTGGCAGATCATGATTTCCAGCCC ACGGAGCCAGCATTTGAACCTTGTATAATTAACTTTCAGTTATGATTTCCCATCGACATT TTCTTTGCCCTGTTTGTAGCTGATTGTTGTGTTTTATAAATCTTCTGTTAAGGCAGAAGG GTGATTATGAGTGGTTCACAGCAGCCCTTATAAGCTGGGCCAGAAAATTTCACTAGGTCA GTAATTTAAACCTTGGATCTTCAAAAAAAAAAAAAAAAAA |
| Restriction Sites | SgfI-XhoI |
| ACCN | NM_006565 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_006565.2, NP_006556.1 |
| RefSeq Size | 3797 bp |
| RefSeq ORF | 2184 bp |
| Locus ID | 10664 |
| UniProt ID | P49711 |
| Domains | zf-C2H2 |
| Protein Families | Transcription Factors |
| Gene Summary | This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010] Transcript Variant: This variant (1) is the longer transcript and encodes the longer isoform (1). |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Epstein-Barr Virus Rta-Mediated Accumulation of DNA Methylation Interferes with CTCF Binding in Both Host and Viral Genomes
,Chen, YJ;Chen, YL;Chang, Y;Wu, CC;Ko, YC;Tsao, SW;Chen, JY;Lin, SF;,
J. Virol.
,PubMed ID 28490592
[CTCF]
|
|
Epigenetic Control of SPI1 Gene by CTCF and ISWI ATPase SMARCA5
,Dluhosova, M;Curik, N;Vargova, J;Jonasova, A;Zikmund, T;Stopka, T;,
PLoS ONE, Feb 2014.
,PubMed ID 24498324
[CTCF]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202416 | CTCF (Myc-DDK-tagged)-Human CCCTC-binding factor (zinc finger protein) (CTCF), transcript variant 1 |
CNY 5,320.00 |
|
| RC202416L1 | Lenti ORF clone of Human CCCTC-binding factor (zinc finger protein) (CTCF), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC202416L2 | Lenti ORF clone of Human CCCTC-binding factor (zinc finger protein) (CTCF), transcript variant 1, mGFP tagged |
CNY 7,728.00 |
|
| RC202416L3 | Lenti ORF clone of Human CCCTC-binding factor (zinc finger protein) (CTCF), transcript variant 1, Myc-DDK-tagged |
CNY 7,728.00 |
|
| RC202416L4 | Lenti ORF clone of Human CCCTC-binding factor (zinc finger protein) (CTCF), transcript variant 1, mGFP tagged |
CNY 7,728.00 |
|
| RG202416 | CTCF (tGFP-tagged) - Human CCCTC-binding factor (zinc finger protein) (CTCF), transcript variant 1 |
CNY 6,928.00 |
|
| SC115994 | CTCF (untagged)-Human CCCTC-binding factor (zinc finger protein) (CTCF), transcript variant 1 |
CNY 2,950.00 |
