CMKLR1 (NM_001142345) Human Untagged Clone

CAT#: SC325015

CMKLR1 (untagged)-Human chemokine-like receptor 1 (CMKLR1), transcript variant 4



  "NM_001142345" in other vectors (4)

CNY 7,220.00


货期*
5周

规格
    • 10 ug

Product images

经常一起买 (4)
Rabbit Polyclonal Anti-CMKLR1 Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms CHEMERINR; ChemR23; DEZ; RVER1
Vector pCMV6 series
Sequence Data
>NCBI ORF sequence for NM_001142345, the custom clone sequence may differ by one or more nucleotides
ATGAGAATGGAGGATGAAGATTACAACACTTCCATCAGTTACGGTGATGAATACCCTGAT
TATTTAGACTCCATTGTGGTTTTGGAGGACTTATCCCCCTTGGAAGCCAGGGTGACCAGG
ATCTTCCTGGTGGTGGTCTACAGCATCGTCTGCTTCCTCGGGATTCTGGGCAATGGTCTG
GTGATCATCATTGCCACCTTCAAGATGAAGAAGACAGTGAACATGGTCTGGTTCCTCAAC
CTGGCAGTGGCAGATTTCCTGTTCAACGTCTTCCTCCCAATCCATATCACCTATGCCGCC
ATGGACTACCACTGGGTTTTCGGGACAGCCATGTGCAAGATCAGCAACTTCCTTCTCATC
CACAACATGTTCACCAGCGTCTTCCTGCTGACCATCATCAGCTCTGACCGCTGCATCTCT
GTGCTCCTCCCTGTCTGGTCCCAGAACCACCGCAGCGTTCGCCTGGCTTACATGGCCTGC
ATGGTCATCTGGGTCCTGGCTTTCTTCTTGAGTTCCCCATCTCTCGTCTTCCGGGACACA
GCCAACCTGCATGGGAAAATATCCTGCTTCAACAACTTCAGCCTGTCCACACCTGGGTCT
TCCTCGTGGCCCACTCACTCCCAAATGGACCCTGTGGGGTATAGCCGGCACATGGTGGTG
ACTGTCACCCGCTTCCTCTGTGGCTTCCTGGTCCCAGTCCTCATCATCACAGCTTGCTAC
CTCACCATCGTGTGCAAACTGCAGCGCAACCGCCTGGCCAAGACCAAGAAGCCCTTCAAG
ATTATTGTGACCATCATCATTACCTTCTTCCTCTGCTGGTGCCCCTACCACACACTCAAC
CTCCTAGAGCTCCACCACACTGCCATGCCTGGCTCTGTCTTCAGCCTGGGTTTGCCCCTG
GCCACTGCCCTTGCCATTGCCAACAGCTGCATGAACCCCATTCTGTATGTTTTCATGGGT
CAGGACTTCAAGAAGTTCAAGGTGGCCCTCTTCTCTCGCCTGGTCAATGCTCTAAGTGAA
GATACAGGCCACTCTTCCTACCCCAGCCATAGAAGCTTTACCAAGATGTCATCAATGAAT
GAGAGGACTTCTATGAATGAGAGGGAGACCGGCATGCTT
Restriction Sites Please inquire     
ACCN NM_001142345
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_001142345.1, NP_001135817.1
RefSeq Size 5110 bp
RefSeq ORF 1122 bp
Locus ID 1240
UniProt ID Q99788
Protein Families Druggable Genome, GPCR, Transmembrane
Gene Summary Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).[UniProtKB/Swiss-Prot Function]
Transcript Variant: This variant (4) differs in the 5' UTR, compared to variant 1. It encodes isoform a.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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