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INAVA (NM_001142569) Human Untagged Clone
CAT＃: SC325209
C1orf106 (untagged)-Human chromosome 1 open reading frame 106 (C1orf106), transcript variant 2
CNY 4,312.00
CNY 7,220.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | C1orf106 |
| Vector | PCMV6-Neo |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_001142569 edited
ATGCTGCAAATGCCGAAGTTAAATGAAATACCTCCGGGGAGGGCAGGCCGCAGGGAGGCT CGGGGGGAGGGAAGATGGCCTGGACAAACAGGTCCTGAAGCTGCGAGGCTGGAGTGGAGG GCGCAGGGGCAGGCGGGCGGCGCCAGAGCTCCATGGGACAGCTGGGGAAGCTCCAGGCTA CCTACACAACCTGGCCCAGGCTGGTCACGGTGTCCCCCGTCCCTGCTCTGTGCCCTCTCC TTCCAGAAATCCACCATGGAGAGTAAGGATGAGGTCAGCGACACCGACAGTGGCATCATC CTGCAGTCTGGCCCCGACAGCCCGGTCTCCCCAATGAAGGAGCTGACCCATGCAGTGCAC AAGCAGCAGAGGGCCCTGGAAGCGAGGCTGGAGGCCTGCCTGGAGGAGCTGAGGAGACTC TGCCTTCGGGAAGCGGAGCTGACGGGCACCTTGCCAGCGGAGTATCCCCTCAAACCAGGG GAAAAGGCCCCCAAGGTTCGCCGCAGGATCGGAGCGGCTTACAAACTGGATGACTGGGCC TTGCACAGAGAGGACCCCCTAAGCAGCCTGGAGCGCCAGCTGGCCCTGCAGCTGCAGATC ACAGAGGCAGCCCGTCGGCTGTGCCTGGAGGAGAACCTCAGCAGGCAGGCTCGGCGGCAG CGGAAGCACTCCATGCTGCAGGAGGAGAAGAAGCTGCAGGAGCTCCAGCGCTGCCTGGTC GAGCGGCGGCGCAATAGCGAGCCACCTCCGGCTGCTGCTCTCCCCCTGGGCCGAGAGCTC AGTGCCTCTGATGACAGCTCCCTGTCAGATGGGCTCCTCCTGGAGGAAGAGGAATCCCAA GTGCCAAAACCTCCTCCAGAGTCTCCAGCCCCACCTTCTCGGCCTCTCCCACCCCAAACC CTTGAGGGTCTGCAGCCAACAGGACCTGAGGCTGGGAGCCCAGAACGGGCTCCAGTCCAG AACAGCCCCTGGAAGGAAACCAGCCTGGACCACCCCTATGAGAAGCCCAGGAAGTCTTCT GAGCCCTGGAGCGAGTCCAGCAGCCCAGCCACCACACCACAGGATGGGCCCAGTGCCTCC AGCCTGTGGCTTCTGGAGCCTGCCTCCTACCACGTGGTTCCCATCCGTGGTGTTCCTGGC CAGTGGCAGGGCCGCACCAGTGCCCCAGCCACCCCTGAGATACAGGGGAGGAGGGGCCAG TCGCAGTCTCTGAGGGTGGATTCCTTCCGGGCGGGTCCTGAGGGCCGAGGTCGCAGCGCC TTTCCCCGCCGCCGCCCCACTCACTACACGGTGACAGTGCCAGATTCCTGCTTTCCCGCG ACCAAGCCCCCGCTGCCCCACGCCGCCTGCCACTCCTGCTCAGAAGACAGTGGCTCTGAC GTCTCCAGCATCTCCCACCCCACTTCGCCGGGCAGCAGCAGCCCCGACATCTCCTTTCTG CAGCCTCTCTCCCCTCCCAAGACCCATCGTCACCGCGGGGCCTGGGTCCCAGCCGGCAGC AGAGAGCTGGTCGCCCACCACCCCAAGCTACTGCTGCCGCCTGGCTATTTCCCGGCGGGG CGGTACGTGGTGGTGGCTGAGAGCCCCCTGCCGCCTGGCGAGTGGGAGCTGTGCCGCGCA GCCCCGGGCCCTGCTTACGAGGAGGAGGGCACTCCCCTGCGCTACCAGCGTCTGGTGCCC TCCCGCAGCCGCATCGTGCGGACGCCCTCCCTGAAGGACAGCCCGGCAGGCCGGGGGCTC AGCAAGGCCGCCGTGTCCGAGGAGCTCAAGTGGTGGCACGAGCGTGCACGCCTCCGGAGC ACCCGACCCCACTCACTGGACCGCCAAGGAGCTTTCCGGGTCAGGAGCCTGCCCCTTGGG AGAGAGGGCTTCGGACGAGCCCTGGGACCCCGGGCACAGGTGCCCACAGTTTGTGTGCTG CGGAGATCGCCTGATGGGGCCCCTGTGCAAGTCTTTGTACCTGAAAAAGGAGAGATCATC AGCCAGGTGTAACTCTGCGCCCCACGCTGGAAAAAACTGTTTCATAGAGGGGCTGGGCTG AGACCCCCCAACCCCTGAGTGCCTCTTTCAGCTCCCCCATCCCCATCGCAGGCCGATGAC CTGGAGCTGAGACCTTTTATTATTTTTTTTTTACACGACTTTTTTCAGAAGCCCTGACCT AAGGATTTATATATGTGGATTGTCCTCAATACCCCTGTGATATGATTATGTTTTATCCCC CAGAGTTTGGCCTACTGGACTTAAGGCCTTGCCTGTCTGACTGACAGCCTCTATCTCCTT ATATAAGACAAGTGGCAGGGGACGAGTGAAGCAGAGTGAGCCACCTTGGG |
| Restriction Sites | Please inquire |
| ACCN | NM_001142569 |
| Insert Size | 4225 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001142569.1, NP_001136041.1 |
| RefSeq Size | 4225 bp |
| RefSeq ORF | 1737 bp |
| Locus ID | 55765 |
| UniProt ID | Q3KP66 |
| Gene Summary | Expressed in peripheral macrophages and intestinal myeloid-derived cells, is required for optimal PRR (pattern recognition receptor)-induced signaling, cytokine secretion, and bacterial clearance. Upon stimulation of a broad range of PRRs (pattern recognition receptor) such as NOD2 or TLR2, TLR3, TLR4, TLR5, TLR7 and TLR9, associates with YWHAQ/14-3-3T, which in turn leads to the recruitment and activation of MAP kinases and NF-kappa-B signaling complexes that amplifies PRR-induced downstream signals and cytokine secretion (PubMed:28436939). In the intestine, regulates adherens junction stability by regulating the degradation of CYTH1 and CYTH2, probably acting as substrate cofactor for SCF E3 ubiquitin-protein ligase complexes. Stabilizes adherens junctions by limiting CYTH1-dependent ARF6 activation (PubMed:29420262).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream translational start codon, compared to variant 1. The encoded isoform (2) is shorter at the N-terminus, compared to isoform 1. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC226874 | C1orf106 (Myc-DDK-tagged)-Human chromosome 1 open reading frame 106 (C1orf106), transcript variant 2 |
CNY 4,304.00 |
|
| RC226874L3 | Lenti ORF clone of Human chromosome 1 open reading frame 106 (C1orf106), transcript variant 2, Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC226874L4 | Lenti ORF clone of Human chromosome 1 open reading frame 106 (C1orf106), transcript variant 2, mGFP tagged |
CNY 6,460.00 |
|
| RG226874 | C1orf106 (tGFP-tagged) - Human chromosome 1 open reading frame 106 (C1orf106), transcript variant 2 |
CNY 5,040.00 |
