DMTF1 (NM_001142327) Human Untagged Clone
CAT#: SC325320
DMTF1 (untagged)-Human cyclin D binding myb-like transcription factor 1 (DMTF1), transcript variant 2
CNY 7,220.00
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | DMP1; DMTF; hDMP1; MRUL |
Vector | pCMV6 series |
Sequence Data |
>NCBI ORF sequence for NM_001142327, the custom clone sequence may differ by one or more nucleotides
ATGAGCACAGTGGAAGAGGATTCTGACACAGTAACAGTAGAAACTGTGAACTCTGTGACT TTGACTCAGGACACAGAAGGGAATCTCATTCTTCACTGCCCTCAGAATGAAGCGGATGAA ATAGACTCAGAAGATAGTATTGAACCTCCACATAAAAGGCTTTGTTTGTCCTCTGAGGAT GATCAGAGTATTGATGATTCTACTCCTTGCATATCAGTTGTTGCACTTCCACTTTCAGAA AATGATCAGAGCTTTGAAGTGACCATGACTGCAACCACAGAAGTAGCAGATGATGAGGTT ACTGAGGGGACTGTGACACAGATACAGATTTTGCAGAATGAGCAACTAGATGAAATATCT CCCTTGGGTAACGAGGAAGTTTCAGCAGTTAGCCAAGCATGGTTTACAACTAAAGAAGAT AAGGATTCTCTGACTAATAAAGGACATAAATGGAAGCAGGGGATGTGGTCCAAGGAAGAA ATTGATATTTTGATGAACAATATTGAACGCTATCTTAAGGCACGCGGAATAAAAGATGCT ACAGAAATCATCTTTGAGATGTCAAAAGACGAAAGAAAAGATTTCTACAGGACTATAGCA TGGGGTCTGAACCGGCCTTTGTTTGCAGTTTATAGAAGAGTGCTTCGCATGTATGATGAC AGAAACCATGTGGGAAAATATACACCTGAAGAAATTGAGAAGCTCAAGGAGCTCCGGATA AAGCATGGCAATGACTGGGCAACAATAGGGGCGGCGCTAGGAAGAAGTGCATCTTCTGTC AAAGATCGGTGCCGACTGATGAAGGATACTTGCAACACAGGGAAGTGGACAGAAGAAGAA GAAAAGAGACTTGCAGAAGTGGTTCATGAGTTGACAAGCACTGAGCCAGGTGACATAGTC ACACAGGGTGTGTCTTGGGCAGCTGTGGCTGAACGAGTCGGTACCCGCTCAGAAAAGCAA TGTCGTTCTAAATGGCTCAACTACCTGAATTGGAAACAGAGTGGGGGTACTGAATGGACC AAGGAAGATGAAATCAATCTCATCCTCAGGATAGCAGAACTTGATGTAGCTGATGAAAAT GACATTAACTGGGATCTGTTAGCTGAGGGATGGAGTAGTGTCCGTTCACCACAATGGCTA CGAAGTAAATGGTGGACCATCAAAAGGCAAATTGCAAACCATAAGGATGTTTCGTTCCCT GTCTTAATAAAAGGTCTTAAACAGTTACATGAGAACCAAAAAAACAACCCAACGCTTTTG GAGAATAAATCAGGATCTGGAGTTCCAAACAGTAATACCAATTCCAGTGTGCAGCATGTT CAGATAAGAGTTGCCCGCTTGGAAGATAATACAGCCATCTCTTCTAGCCCCATGGCAGCA TTGCAGATTCCAGTCCAGATCACCCATGTTTCTTCAGCAGACTCTCCTGCTACCGTTGAC TCAGAAACAATAACACTAAACAGTGGAACACTACAGACATTTGAGATTCTTCCCTCTTTC CATCTACAGCCCACTGGCACTCCAGGCACCTACCTACTTCAAACAAGCTCAAGCCAAGGC CTTCCCCTAACTCTGACTGCTAGTCCCACAGTAACCCTGACAGCTGCTGCTCCTGCTTCT CCTGAACAGATTATTGTTCATGCTTTATCCCCAGAACATTTGTTGAACACAAGTGATAAT GTTACAGTGCAGTGTCACACACCAAGAGTCATCATTCAGACTGTTGCCACAGAGGACATC ACTTCTTCCATATCCCAAGCAGAACTGACAGTCGATAGTGATATTCAGTCATCTGATTTT CCTGAGCCTCCAGACGCCCTAGAAGCAGACACTTTCCCAGATGAAATTCATCACCCTAAG ATGACTGTGGAGCCATCATTTAATGATGCTCATGTATCCAAATTCAGTGACCAAAATAGC ACAGAACTGATGAATAGTGTTATGGTCAGAACAGAAGAAGAAATCTCTGACACCGACCTT AAACAAGAGGAATCACCCTCTGATTTAGCCAGTGCTTATGTTACTGAGGGTTTAGAGTCT CCCACTATAGAAGAACAAGTTGATCAAACAATTGATGATGAAACAATACTTATCGTTCCT TCACCACATGGCTTTATCCAGGCATCTGATGTTATAGATACTGAATCTGTCTTGCCTTTG ACAACACTAACAGATCCCATACTCCAACATCATCAGGAAGAATCAAATATCATTGGATCA TCCTTGGGCAGTCCTGTTTCAGAAGATTCAAAGGATGTCGAAGATTTGGTAAACTGTCAT |
Restriction Sites | Please inquire |
ACCN | NM_001142327 |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001142327.1, NP_001135799.1 |
RefSeq Size | 3801 bp |
RefSeq ORF | 2283 bp |
Locus ID | 9988 |
UniProt ID | Q9Y222 |
Protein Families | Transcription Factors |
Gene Summary | This gene encodes a transcription factor that contains a cyclin D-binding domain, three central Myb-like repeats, and two flanking acidic transactivation domains at the N- and C-termini. The encoded protein is induced by the oncogenic Ras signaling pathway and functions as a tumor suppressor by activating the transcription of ARF and thus the ARF-p53 pathway to arrest cell growth or induce apoptosis. It also activates the transcription of aminopeptidase N and may play a role in hematopoietic cell differentiation. The transcriptional activity of this protein is regulated by binding of D-cyclins. This gene is hemizygously deleted in approximately 40% of human non-small-cell lung cancer and is a potential prognostic and gene-therapy target for non-small-cell lung cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform (a). |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC227951 | DMTF1 (Myc-DDK-tagged)-Human cyclin D binding myb-like transcription factor 1 (DMTF1), transcript variant 2 |
CNY 3,990.00 |
|
RC227951L3 | Lenti-ORF clone of DMTF1 (Myc-DDK-tagged)-Human cyclin D binding myb-like transcription factor 1 (DMTF1), transcript variant 2 |
CNY 5,890.00 |
|
RC227951L4 | Lenti-ORF clone of DMTF1 (mGFP-tagged)-Human cyclin D binding myb-like transcription factor 1 (DMTF1), transcript variant 2 |
CNY 5,890.00 |
|
RG227951 | DMTF1 (tGFP-tagged) - Human cyclin D binding myb-like transcription factor 1 (DMTF1), transcript variant 2 |
CNY 4,370.00 |