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XPC (NM_001145769) Human Untagged Clone
CAT＃: SC326630
XPC (untagged)-Human xeroderma pigmentosum, complementation group C (XPC), transcript variant 2, mRNA
CNY 17,390.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | RAD4; XP3; XPCC |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_001145769, the custom clone sequence may differ by one or more nucleotides
ATGGCTCGGAAACGCGCGGCCGGCGGGGAGCCGCGGGGACGCGAACTGCGCAGCCAGAAA TCCAAGGCCAAGAGCAAGGCCCGGCGTGAGGAGGAGGAGGAGGATGCCTTTGAAGATGAG AAACCCCCAAAGAAGAGCCTTCTCTCCAAAGTTTCACAAGGAAAGAGGAAAAGAGGCTGC AGTCATCCTGGGGGTTCAGCAGATGGTCCAGCAAAAAAGAAAGTGGCCAAGGTGACTGTT AAATCTGAAAACCTCAAGGTTATAAAGGATGAAGCCCTCAGCGATGGGGATGACCTCAGG GACTTTCCAAGTGACCTCAAGAAGGCACACCATCTGAAGAGAGGGGCTACCATGAATGAA GACAGCAATGAAGAAGAGGAAGAAAGTGAAAATGATTGGGAAGAGGCGAAGACAAGAGAA AGAAGTGAAAAGATAAAACTGGAGTTTGAGACATATCTTCGGAGGGCGATGAAACGTTTC AATAAAGGGGTCCATGAGGACACACACAAGGTTCACCTTCTCTGCCTGCTAGCAAATGGC TTCTATCGAAATAACATCTGCAGCCAGCCAGATCTGCATGCTATTGGCCTGTCCATCATC CCAGCCCGCTTTACCAGAGTGCTGCCTCGAGATGTGGACACCTACTACCTCTCAAACCTG GTGAAGTGGTTCATTGGAACATTTACAGTTAATGCAGAACTTTCAGCCAGTGAACAAGAT AACCTGCAGACTACATTGGAAAGGAGATTTGCTATTTACTCTGCTCGAGATGATGAGGAA TTGGTCCATATATTCTTACTGATTCTCCGGGCTCTGCAGCTCTTGACCCGGCTGGTATTG TCTCTACAGCCAATTCCTCTGAAGTCAGCAACAGCAAAGGGAAAGAAACCTTCCAAGGAA AGATTGACTGCGGATCCAGGAGGCTCCTCAGAAACTTCCAGCCAAGTTCTAGAAAACCAC ACCAAACCAAAGACCAGCAAAGGAACCAAACAAGAGGAAACCTTTGCTAAGGGCACCTGC AGGCCAAGTGCCAAAGGGAAGAGGAACAAGGGAGGCAGAAAGAAACGGAGCAAGCCCTCC TCCAGCGAGGAAGATGAGGGCCCAGGAGACAAGCAGGAGAAGGCAACCCAGCGACGTCCG CATGGCCGGGAGCGGCGGGTGGCCTCCAGGGTGTCTTATAAAGAGGAGAGTGGGAGTGAT GAGGCTGGCAGCGGCTCTGATTTTGAGCTCTCCAGTGGAGAAGCCTCTGATCCCTCTGAT GAGGATTCCGAACCTGGCCCTCCAAAGCAGAGGAAAGCCCCCGCTCCTCAGAGGACAAAG GCTGGGTCCAAGAGTGCCTCCAGGACCCATCGTGGGAGCCATCGTAAGGACCCAAGCTTG CCAGCGGCATCCTCAAGCTCTTCAAGCAGTAAAAGAGGCAAGAAAATGTGCAGCGATGGT GAGAAGGCAGAAAAAAGAAGCATAGCTGGTATAGACCAGTGGCTAGAGGTGTTCTGTGAG CAGGAGGAAAAGTGGGTATGTGTAGACTGTGTGCACGGTGTGGTGGGCCAGCCTCTGACC TGTTACAAGTACGCCACCAAGCCCATGACCTATGTGGTGGGCATTGACAGTGACGGCTGG GTCCGAGATGTCACACAGAGGTACGACCCAGTCTGGATGACAGTGACCCGCAAGTGCCGG GTTGATGCTGAGTGGTGGGCCGAGACCTTGAGACCATACCAGAGCCCATTTATGGACAGG GAGAAGAAAGAAGACTTGGAGTTTCAGGCAAAACACATGGACCAGCCTTTGCCCACTGCC ATTGGCTTATATAAGAACCACCCTCTGTATGCCCTGAAGCGGCATCTCCTGAAATATGAG GCCATCTATCCCGAGACAGCTGCCATCCTTGGGTATTGTCGTGGAGAAGCGGTCTACTCC AGGGATTGTGTGCACACTCTGCATTCCAGGGACACGTGGCTGAAGAAAGCAAGAGTGGTG AGGCTTGGAGAAGTACCCTACAAGATGGTGAAAGGCTTTTCTAACCGTGCTCGGAAAGCC CGACTTGCTGAGCCCCAGCTGCGGGAAGAAAATGACCTGGGCCTGTTTGGCTACTGGCAG ACAGAGGAGTATCAGCCCCCAGTGGCCGTGGACGGGAAGGTGCCCCGGAACGAGTTTGGG AATGTGTACCTCTTCCTGCCCAGCATGATGCCTATTGGCTGTGTCCAGCTGAACCTGCCC AATCTACACCGCGTGGCCCGCAAGCTGGACATCGACTGTGTCCAGGCCATCACTGGCTTT GATTTCCATGGCGGCTACTCCCATCCCGTGACTGATGGATACATCGTCTGCGAGGAATTC AAAGACGTGCTCCTGACTGCCTGGGAAAATGAGCAGGCAGTCATTGAAAGGAAGGAGAAG GAGAAAAAGGAGAAGCGGGCTCTAGGGAACTGGAAGTTGCTGGCCAAAGGTCTGCTCATC AGGGAGAGGCTGAAGCGTCGCTACGGGCCCAAGAGTGAGGCAGCAGCTCCCCACACAGAT GCAGGAGGTGGACTCTCTTCTGATGAAGAGGAGGGGACCAGCTCTCAAGCAGAAGCGGCC AGGATACTGGCTGCCTCCTGGCCTCAAAACCGAGAAGATGAAGAAAAGCAGAAGCTGAAG GGTGGGCCCAAGAAGACCAAAAGGGAAAAGAAAGCAGCAGCTTCCCACCTGTTCCCATTT GAGCAGCTG |
| Restriction Sites | Please inquire |
| ACCN | NM_001145769 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001145769.1, NP_001139241.1 |
| RefSeq Size | 3618 bp |
| RefSeq ORF | 2712 bp |
| Locus ID | 7508 |
| Protein Families | Druggable Genome |
| Protein Pathways | Nucleotide excision repair |
| Gene Summary | The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017] Transcript Variant: This variant (2) lacks an internal segment in the CDS, as compared to variant 1. The reading frame is not changed, and the resulting isoform (2) is shorter than isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC226839 | XPC (Myc-DDK-tagged)-Human xeroderma pigmentosum, complementation group C (XPC), transcript variant 2 |
CNY 9,030.00 |
|
| RC226839L3 | Lenti-ORF clone of XPC (Myc-DDK-tagged)-Human xeroderma pigmentosum, complementation group C (XPC), transcript variant 2 |
CNY 10,930.00 |
|
| RC226839L4 | Lenti-ORF clone of XPC (mGFP-tagged)-Human xeroderma pigmentosum, complementation group C (XPC), transcript variant 2 |
CNY 10,930.00 |
|
| RG226839 | XPC (tGFP-tagged) - Human xeroderma pigmentosum, complementation group C (XPC), transcript variant 2 |
CNY 8,872.00 |
