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HERC6 (NM_001165136) Human Untagged Clone
CAT＃: SC327263
HERC6 (untagged)-Human hect domain and RLD 6 (HERC6) transcript variant 2
CNY 19,000.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_001165136, the custom clone sequence may differ by one or more nucleotides
ATGTACTTCTGTTGGGGCGCCGACTCCAGGGAGCTGCAGCGCCGGAGGACGGCGGGCAGC CCCGGGGCTGAGCTACTGCAGGCGGCCAGCGGGGAGCGCCACTCTCTGCTGCTGCTGACC AACCACAGGGTCCTCTCGTGCGGAGACAACAGCAGGGGTCAGCTGGGCCGCAGGGGCGCG CAGCGCGGGGAGCTGCCAGAACCAATTCAGGCATTGGAAACCCTAATTGTTGATCTCGTG AGCTGCGGGAAGGAGCACTCCCTGGCTGTGTGCCACAAAGGAAGGGTCTTCGCATGGGGA GCTGGTTCTGAAGGGCAGCTGGGGATTGGAGAATTCAAGGAAATAAGTTTCACACCTAAG AAAATAATGACTCTGAATGATATAAAAATAATACAAGTTTCCTGTGGACACTACCACTCC CTGGCATTATCAAAAGATAGCCAAGTGTTTTCGTGGGGAAAGAACAGCCATGGGCAGCTG GGCTTGGGGAAGGAGTTCCCCTCCCAAGCCAGCCCGCAGAGGGTGAGGTCCCTGGAGGGG ATCCCACTGGCTCAGGTGGCTGCCGGAGGGGCTCACAGCTTTGCCCTGTCTCTCTGTGGG ACTTCGTTTGGCTGGGGAAGTAACAGTGCCGGGCAGCTGGCCCTCAGTGGGCGTAATGTC CCAGTGCAAAGCAACAAGCCTCTCTCAGTCGGTGCACTGAAGAATCTAGGTGTGGTTTAT ATCAGCTGTGGTGATGCACACACTGCGGTGCTTACCCAGGACGGGAAAGTGTTCACATTT GGAGACAATCGCTCTGGACAGCTGGGATACAGCCCCACTCCTGAGAAGAGAGGTCCACAA CTTGTGGAAAGAATTGATGGCCTAGTTTCGCAGATAGATTGTGGAAGTTATCACACCCTG GCATATGTGCACACCACTGGTCAGGTGGTATCTTTTGGTCATGGACCAAGTGACACAAGC AAGCCAACTCATCCGGAGGCCCTGACAGAGAACTTTGACATTAGCTGCCTGATTTCTGCT GAAGACTTCGTGGATGTTCAAGTCAAACACATTTTTGCTGGAACATATGCCAACTTTGTG ACAACTCATCAGGATACTAGTTCCACACGTGCTCCCGGGAAAACCCTGCCAGAAATAAGC CGAATTAGCCAGTCCATGGCAGAAAAATGGATAGCAGTGAAAAGAAGAAGTACTGAACAT GAAATGGCTAAAAGTGAAATTAGAATGATATTTTCATCTCCTGCTTGTCTGACTGCAAGT TTTTTAAAGAAAAGAGGAACTGGAGAAACGACTTCCATTGATGTGGACTTAGAAATGGCA AGAGATACCTTCAAGAAGTTAACAAAAAAGGAATGGATTTCTTCCATGATAACTACGTGT CTCGAGGATGATCTGCTCAGAGCTCTTCCATGCCATTCTCCACACCAAGAAGCTTTATCA GTTTTCCTCCTGCTCCCAGAATGTCCTGTGATGCATGATTCTAAGAACTGGAAGAACCTG GTGGTTCCATTTGCAAAGGCTGTGTGTGAAATGAGTAAACAATCTTTGCAAGTCCTAAAG AAGTGTTGGGCATTTTTGCAAGAATCTTCTCTGAATCCGCTGATCCAGATGCTTAAAGCA GCCATCATCTCTCAGCTGCTTCATCAGACTAAAACCGAACAGGATCACTGTAATGTTAAA GCTCTTTTAGGAATGATGAAAGAACTGCATAAGGTAAACAAAGCTAACTGTCGACTACCA GAAAATACTTTCAACATAAATGAACTCTCCAACTTATTAAACTTTTATATAGATAGAGGA AGACAGCTCTTTCGGGATAACCACCTGATGTCAGAAAAGAAAGCATACATGCTTATGCAT GAAACAATTCTGCAAAAAAAGGATGAATTTCCTCCATCACCCAGATTTATACTTAGAGTC AGACGAAGTCGCCTGGTTAAAGATGCTCTGCGTCAATTAAGTCAAGCTGAAGCTACTGAC TTCTGCAAAGTATTAGTGGTTGAATTTATTAATGAAATTTGTCCTGAGTCTGGAGGGGTT AGTTCAGAGTTCTTCCACTGTATGTTTGAAGAGATGACCAAGCCAGAATATGGAATGTTC ATGTATCCTGAAATGGGTTCCTGCATGTGGTTTCCTGCCAAGCCTAAACCTGAGAAGAAA AGATATTTCCTCTTTGGAATGCTGTGTGGACTCTCCTTATTCAATTTAAATGTTGCTAAC CTTCCTTTCCCACTGGCTCTGTATAAAAAACTTCTGGACCAAAAGCCATCATTGGAAGAT TTAAAAGAACTCAGTCCTCGGTTGGGGAAGAGTTTGCAAGAAGTTCTAGATGATGCTGCT GATGACATTGGAGATGCGCTCTGCATACGCTTTTCTATACACTGGGACCAAAATGATGTT GACTTAATTCCAAATGGGATCTCCATACCTGTGGACCAAACCAACAAGAGAGACTATGTT TCTAAGTATATTGATTACATTTTCAACGTCTCTGTAAAAGCAGTTTATGAGGAATTTCAG AGAGGATTTTATAGAGTCTGTGAGAAGGAGATACTTAGACATTTCTACCCTGAAGAACTA ATGACAGCAATCATTGGAAATACTGATTATGACTGGAAACAGTTTGAACAGAATTCAAAG TATGAGCAAGGATACCAAAAATCACATCCTACTATACAGTTGTTTTGGAAGGCTTTCCAC AAACTAACCTTGGATGAAAAGAAAAAATTCCTCTTTTTCCTTACAGGACGTGATAGGCTG CATGCAAGAGGCATACAGAAAATGGAAATAGTATTTCGCTGTCCTGAAACTTTCAGTGAA AGAGATCACCCAACATCAATAACTTGTCATAATATTCTCTCCCTCCCTAAGTATTCTACA ATGGAAAGAATGGAGGAAGCACTTCAAGTAGCCATCAACAACAACAGAGGATTTGTCTCA CCCATGCTCACACAGTCA |
| Restriction Sites | Please inquire |
| ACCN | NM_001165136 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001165136.1, NP_001158608.1 |
| RefSeq Size | 3781 bp |
| RefSeq ORF | 2961 bp |
| Locus ID | 55008 |
| UniProt ID | Q8IVU3 |
| Protein Families | Druggable Genome |
| Gene Summary | HERC6 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).[supplied by OMIM, Mar 2008] Transcript Variant: This variant (2) lacks an alternate in-frame exon in the central coding region, compared to variant 1. The resulting isoform (2) lacks an internal segment, compared to isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC228628 | HERC6 (Myc-DDK-tagged)-Human hect domain and RLD 6 (HERC6), transcript variant 2 |
CNY 9,790.00 |
|
| RC228628L3 | Lenti-ORF clone of HERC6 (Myc-DDK-tagged)-Human hect domain and RLD 6 (HERC6), transcript variant 2 |
CNY 11,690.00 |
|
| RC228628L4 | Lenti-ORF clone of HERC6 (mGFP-tagged)-Human hect domain and RLD 6 (HERC6), transcript variant 2 |
CNY 11,690.00 |
|
| RG228628 | HERC6 (tGFP-tagged) - Human hect domain and RLD 6 (HERC6), transcript variant 2 |
CNY 10,740.00 |
