PLEKHN1 (NM_001160184) Human Untagged Clone

CAT#: SC327601

PLEKHN1 (untagged)-Human pleckstrin homology domain containing family N member 1 (PLEKHN1) transcript variant 2



  "NM_001160184" in other vectors (4)

CNY 7,220.00


货期*
5周

规格
    • 10 ug

Product images

经常一起买 (3)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms CLPABP
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for NM_001160184, the custom clone sequence may differ by one or more nucleotides
ATGGGGAACAGCCACTGTGTCCCTCAGGCCCCCAGGAGGCTCCGGGCCTCCTTCTCCAGA
AAGCCCTCGCTGAAGGGAAACAGAGAGGACAGCGCGCGGATGTCGGCCGGCCTGCCGGGC
CCCGAGGCTGCTCGAAGCGGGGACGCCGCCGCCAACAAGCTCTTCCACTACATCCCGGGC
ACGGACATCCTGGACCTGGAGAACCAGCGAGAAAACCTGGAGCAGCCATTCCTGAGTGTG
TTCAAGAAGGGGCGGCGGAGGGTGCCTGTGAGGAACCTGGGAAAAGTTGTGCATTACGCC
AAGGTCCAGCTGCGGTTCCAGCACAGCCAGGATGTCAGCGACTGCTACCTGGAGCTATTC
CCCGCCCACCTGTACTTCCAGGCCCACGGCTCGGAAGGACTCACATTTCAGGGGCTGTTA
CCGCTGACGGAGCTGAGTGTCTGCCCGCTCGAGGGGTCCCGAGAGCACGCCTTCCAGATC
ACAGGCCCACTGCCCGCACCCCTCCTGGTGCTCTGCCCCAGCCGGGCCGAGCTGGACCGC
TGGCTTTACCACCTGGAGAAGCAGACGGCCCTCCTCGGGGGGCCGCGGCGCTGCCACTCG
GCACCCCCACAGGGGTCCTGCGGAGACGAACTCCCCTGGACTTTGCAGCGCCGTCTAACC
CGGCTGCGGACGGCGTCAGGGCACGAACCCGGCGGCAGTGCTGTCTGTGCCTCGAGGGTC
AAGCTGCAGCACCTGCCCGCACAGGAGCAGTGGGACCGGCTCTTGGTCCTGTACCCAACG
TCCTTGGCCATTTTCTCCGAGGAGCTGGACGGGCTTTGCTTCAAGGGGGAGCTCCCACTC
CGTGCCGTCCACATCAACCTGGAGGAGAAGGAGAAGCAGATCCGCTCCTTCCTGATTGAA
GGCCCCCTCATCAACACCATCCGCGTGGTGTGCGCCAGCTACGAGGACTACGGTCACTGG
CTGCTGTGCCTTCGCGCTGTCACCCACAGGGAGGGGGCCCCGCCGCTGCCTGGTGCCGAG
AGCTTCCCAGGGTCGCAGGTTATGGGCAGTGGCCGAGGCTCACTCTCCTCAGGCGGACAG
ACCAGCTGGGACTCGGGGTGCTTGGCGCCCCCCTCCACCCGCACCAGCCACTCCCTGCCT
GAGTCCTCAGTGCCATCCACCGTGGGCTGCTCCTCCCAGCACACACCGCTGCACAGGCTG
AGCCTGGAGAGCAGCCCAGATGCCCCTGACCACACTTCGGAAACATCACACTCGCCCCTC
TATGCCGACCCCTACACACCACCCGCCACCTCCCACCGCAGGGTCACAGATGTCCGGGGC
CTGGAGGAGTTCCTCAGTGCCATGCAGAGTGCACGTGGACCCACGCCCTCGAGCCCACTC
CCCTCGGTGCCTGTGTCTGTGCCTGCCTCTGACCCTCGCTCCTGCTCCTCCGGCCCCGCT
GGCCCCTACTTGCTCTCCAAGAAGGGAGCCCTGCAGTCCAGAGCCGCTCAGAGACACCGG
GGCTCAGCCAAGGATGGGGGGCCGCAGCCCCCAGACGCCCCTCAGCTTGTCTCCTCTGCC
AGGGAAGGTTCGCCCGAACCCTGGCTGCCTCTGACAGATGGTCGGTCCCCCAGGAGGAGC
CGGGACCCCGGCTACGACCACCTCTGGGACGAGACTTTGTCTTCCTCCCACCAGAAGTGC
CCCCAGCTTGGAGGGCCTGAGGCCAGTGGGGGGCTTGTGCAGTGGATC
Restriction Sites Please inquire     
ACCN NM_001160184
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_001160184.1, NP_001153656.1
RefSeq Size 2299 bp
RefSeq ORF 1731 bp
Locus ID 84069
UniProt ID Q494U1
Gene Summary Controls the stability of the leptin mRNA harboring an AU-rich element (ARE) in its 3' UTR, in cooperation with the RNA stabilizer ELAVL1 (PubMed:29180010). Decreases the stability of the leptin mRNA by antagonizing the function of ELAVL1 by inducing its atypical recruitment from the nucleus to the cytosol (By similarity). Binds to cardiolipin (CL), phosphatidic acid (PA), phosphatidylinositol 4-phosphate (PtdIns(4)P) and phosphatidylserine (PS) (PubMed:18191643). Promotes apoptosis by enhancing BAX-BAK hetro-oligomerization via interaction with BID in colon cancer cells (PubMed:29531808) (By similarity).[UniProtKB/Swiss-Prot Function]
Transcript Variant: This variant (2) has multiple differences in the coding region but maintains the reading frame, compared to variant 1. This variant encodes isoform b which is shorter than isoform a.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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