Transglutaminase 6 (TGM6) (NM_001254734) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	dJ734P14.3; SCA35; TG6; TGM3L; TGY
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC330322 representing NM_001254734. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGGCAGGGATCAGAGTCACCAAGGTGGACTGGCAGCGGTCGAGGAATGGCGCTGCCCACCACACCCAG GAGTACCCCTGCCCTGAGCTGGTGGTTCGCAGGGGCCAGTCGTTCAGCCTCACGCTGGAGCTGAGCAGA GCCCTGGACTGTGAGGAGATCCTCATCTTCACGATGGAGACAGGACCCCGGGCTTCTGAGGCCCTCCAC ACCAAAGCTGTGTTCCAGACATCGGAGCTGGAGCGGGGTGAGGGCTGGACAGCAGCAAGGGAGGCTCAG ATGGAGAAAACTCTGACCGTCAGTCTCGCCAGCCCTCCCAGTGCTGTCATTGGCCGCTACCTGCTGAGC ATCAGGCTTTCCTCTCACCGCAAACACAGCAACCGGAGGCTGGGCGAGTTTGTTCTCCTTTTCAACCCA TGGTGTGCAGAGGACGATGTGTTTCTGGCCTCAGAGGAGGAGAGACAGGAGTACGTGCTCAGCGACAGC GGCATCATCTTCCGAGGCGTGGAGAAGCACATACGAGCCCAGGGCTGGAACTACGGGCAGTTTGAGGAG GACATCCTGAACATCTGCCTCTCCATCCTGGATCGAAGCCCCGGTCACCAAAACAACCCAGCCACCGAC GTGTCCTGCCGCCACAACCCCATCTACGTCACCAGGGTCATCAGTGCCATGGTGAACAGCAACAACGAC CGAGGTGTGGTGCAAGGACAGTGGCAGGGCAAGTACGGCGGCGGCACCAGCCCGCTGCACTGGCGCGGC AGCGTGGCCATTCTGCAGAAGTGGCTCAAGGGCAGGTACAAGCCAGTCAAGTACGGCCAGTGCTGGGTC TTCGCCGGAGTCCTGTGCACAGTCCTCAGGTGCTTGGGGATAGCCACACGGGTCGTGTCCAACTTCAAC TCAGCCCACGACACAGACCAGAACCTGAGTGTGGACAAATACGTGGACTCCTTCGGGCGGACCCTGGAG GACCTGACAGAAGACAGCATGTGGAATTTCCATGTCTGGAATGAGAGCTGGTTTGCCCGGCAGGACCTA GGCCCCTCTTACAATGGCTGGCAGGTTCTGGATGCCACCCCCCAGGAGGAGAGTGAAGGTGTGTTCCGG TGCGGCCCAGCCTCAGTCACCGCCATCCGCGAGGGTGATGTGCACCTGGCTCACGATGGCCCCTTCGTG TTTGCGGAGGTCAACGCCGACTACATCACCTGGCTGTGGCACGAGGATGAGAGCCGGGAGCGTGTATAC TCAAACACGAAGAAGATTGGGAGATGCATCAGCACCAAGGCGGTGGGCAGTGACTCCCGCGTGGACATC ACTGACCTCTACAAGTATCCGGAAGGGTCCCGGAAAGAGAGGCAGGTGTACAGCAAGGCGGTGAACAGG CTGTTCGGCGTGGAAGCCTCTGGAAGGAGAATCTGGATCCGCAGGGCTGGGGGTCGCTGTCTCTGGCGT GACGACCTCCTGGAGCCTGCCACCAAGCCCAGCATCGCTGGCAAGTTCAAGGTGCTAGAGCCTCCCATG CTGGGCCACGACCTGAGACTGGCCCTGTGCTTGGCCAACCTCACCTCCCGGGCCCAGCGGGTGAGGGTC AACCTGAGCGGTGCCACCATCCTCTATACCCGCAAGCCAGTGGCAGAGATCCTGCATGAATCCCACGCC GTGAGGCTGGGGCCGCAAGAAGAGAAGAGAATCCCAATTACAATATCTTACTCTAAGTATAAAGAAGAC CTGACAGAGGACAAGAAGATCCTGTTGGCTGCCATGTGCCTTGTCACCAAAGGAGAGAAGCTTCTGGTG GAGAAGGACATTACTCTAGAGGACTTCATCACCATCAAGCGTGCCTACCCTGGAGCCTCAGGAGAGGGC CTCAGTCCAGTTTGA
Restriction Sites	SgfI-MluI
ACCN	NM_001254734
Insert Size	1878 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	NM_001254734.1
RefSeq Size	2158 bp
RefSeq ORF	1878 bp
Locus ID	343641
UniProt ID	O95932
Protein Families	Druggable Genome
MW	70.5 kDa
Gene Summary	The protein encoded by this gene belongs to the transglutaminase superfamily. It catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Mutations in this gene are associated with spinocerebellar ataxia type 35 (SCA35). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] Transcript Variant: This variant (2) lacks a coding exon in the 3' region compared to variant 1. This results in a frame-shift, and a shorter isoform (2) with a distinct C-terminus compared to isoform 1.

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