SEPTIN4 (NM_001256822) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	ARTS; BRADEION; C17orf47; CE5B3; H5; hCDCREL-2; hucep-7; MART; PNUTL2; SEP4; SEPT4
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC330525 representing NM_001256822. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGGTGGCAGGAGAGTCTGGCCTGGGCAAATCCACACTTGTCAATAGCCTCTTCCTCACTGATCTGTAC CGGGACCGGAAACTTCTTGGTGCTGAAGAGAGGATCATGCAAACTGTGGAGATCACTAAGCATGCAGTG GACATAGAAGAGAAGGGTGTGAGGCTGCGGCTCACCATTGTGGACACACCAGGTTTTGGGGATGCAGTC AACAACACAGAGTGCTGGAAGCCTGTGGCAGAATACATTGATCAGCAGTTTGAGCAGTATTTCCGAGAC GAGAGTGGCCTGAACCGAAAGAACATCCAAGACAACAGGGTGCACTGCTGCCTGTACTTCATCTCACCC TTCGGCCATGGGCTCCGGCCATTGGATGTTGAATTCATGAAGGCCCTGCATCAGCGGGTCAACATCGTG CCTATCCTGGCTAAGGCAGACACACTGACACCTCCCGAAGTGGACCACAAGAAACGCAAAATCCGGGAG GAGATTGAGCATTTTGGAATCAAGATCTATCAATTCCCAGACTGTGACTCTGATGAGGATGAGGACTTC AAATTGCAGGACCAAGCCCTAAAGGAAAGCATCCCATTTGCAGTAATTGGCAGCAACACTGTAGTAGAG GCCAGAGGGCGGCGAGTTCGGGGTCGACTCTACCCCTGGGGCATCGTGGAAGTGGAAAACCCAGGGCAC TGCGACTTTGTGAAGCTGAGGACAATGCTGGTACGTACCCACATGCAGGACCTGAAGGATGTGACACGG GAGACACATTATGAGAACTACCGGGCACAGTGCATCCAGAGCATGACCCGCCTGGTGGTGAAGGAACGG AATCGCAACAAACTGACTCGGGAAAGTGGTACCGACTTCCCCATCCCTGCTGTCCCACCAGGGACAGAT CCAGAAACTGAGAAGCTTATCCGAGAGAAAGATGAGGAGCTGCGGCGGATGCAGGAGATGCTACACAAA ATACAAAAACAGATGAAGGAGAACTATTAA
Restriction Sites	SgfI-MluI
ACCN	NM_001256822
Insert Size	996 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001256822.1
RefSeq Size	1777 bp
RefSeq ORF	996 bp
Locus ID	5414
UniProt ID	O43236
MW	38.5 kDa
Gene Summary	This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer. [provided by RefSeq, Nov 2010] Transcript Variant: This variant (6) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 7. The encoded isoform (6) is shorter than isoform 5.

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