LRBA (NM_001199282) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	BGL; CDC4L; CVID8; LAB300; LBA
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC331290 representing NM_001199282. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGGCTAGCGAAGACAATCGTGTCCCTTCCCCGCCACCAACAGGTGATGACGGGGGAGGTGGAGGGAGA GAAGAAACCCCTACTGAAGGGGGTGCATTGTCTCTGAAACCAGGGCTCCCCATCAGGGGCATCAGAATG AAATTTGCCGTGTTGACCGGTTTGGTTGAAGTTGGAGAAGTATCCAATAGGGATATTGTAGAAACTGTC TTTAACCTGTTGGTAGGAGGACAGTTTGATCTGGAAATGAATTTCATTATCCAAGAAGGTGAGAGTATT AACTGCATGGTGGACCTACTGGAAAAATGTGACATTACGTGCCAAGCAGAAGTCTGGAGCATGTTTACA GCCATTCTGAAGAAAAGCATACGGAATCTTCAAGTCTGCACTGAAGTAGGCCTTGTTGAAAAAGTGCTT GGGAAAATTGAAAAAGTTGACAATATGATAGCAGATCTTTTGGTTGACATGTTGGGAGTGCTGGCTAGC TATAATTTGACAGTTCGCGAGCTAAAGCTTTTCTTCAGTAAACTTCAAGGAGATAAAGGACGATGGCCT CCACATGCTGGGAAGTTGCTGTCTGTGTTAAAGCATATGCCTCAGAAGTATGGTCCTGATGCCTTTTTT AACTTTCCAGGAAAGAGTGCTGCAGCTATTGCATTACCTCCTATAGCCAAATGGCCATACCAGAATGGT TTTACATTTCATACATGGCTTAGAATGGATCCTGTAAATAACATCAATGTAGATAAGGATAAACCATAT TTGTATTGTTTCAGAACCAGCAAAGGTCTTGGCTATTCTGCTCATTTTGTTGGAGGCTGTTTGATTGTA ACATCAATAAAGTCAAAAGGAAAAGGCTTTCAACACTGTGTGAAATTTGATTTCAAGCCACAAAAGTGG TATATGGTTACCATAGTACACATCTATAACCGATGGAAGAATAGTGAACTTCGATGTTATGTGAATGGT GAGCTGGCTTCCTATGGAGAGATAACATGGTTTGTCAACACTAGCGATACCTTTGACAAATGTTTCCTG GGCTCATCAGAAACAGCAGATGCTAATAGAGTATTCTGTGGTCAGATGACTGCAGTTTACCTTTTCAGT GAAGCTCTAAATGCAGCTCAGATATTTGCTATTTATCAGTTGGGCCTGGGATACAAGGGTACATTTAAA TTCAAAGCAGAAAGCGACCTTTTCCTTGCTGAGCATCACAAACTTTTATTGTACGATGGGAAACTCTCT AGTGCCATTGCATTCACGTACAATCCACGGGCTACAGATGCCCAGCTTTGTCTTGAATCATCTCCTAAG GACAACCCTTCAATTTTTGTTCATTCACCACATGCACTCATGCTCCAGGATGTAAAGGCAGTTTTAACA CATTCCATCCAAAGTGCAATGCATTCAATTGGAGGAGTACAAGTACTATTTCCACTTTTTGCACAGTTG GATTACAGGCAATATTTGTCTGATGAGATTGATTTGACTATATGTTCAACCTTGCTGGCCTTTATCATG GAATTGTTGAAGAACTCAATTGCTATGCAGGAACAGATGCTTGCCTGTAAGGGCTTCTTGGTAATAGGA TATAGCCTTGAAAAGTCTTCCAAATCTCATGTTAGCAGAGCAGTACTTGAACTTTGCCTTGCATTTTCA AAATATCTGAGTAATCTGCAGAATGGGATGCCCCTGCTCAAGCAATTGTGTGATCACGTTCTTCTTAAT CCTGCCATATGGATTCATACCCCAGCCAAGGTTCAACTGATGCTCTATACTTATCTGTCCACGGAATTC ATTGGTACAGTCAACATATATAACACCATTCGGAGAGTTGGAACAGTGCTTCTCATCATGCACACGCTG AAGTACTACTACTGGGCAGTGAATCCTCAGGATCGAAGTGGTATCACCCCAAAAGGATTAGATGGACCG CGACCTAATCAAAAAGAAATGCTTTCTCTACGAGCATTCTTGTTGATGTTCATTAAGCAATTAGTGATG AAGGATTCTGGAGTAAAGGAAGATGAATTACAGGCCATTCTTAATTACCTACTGACTATGCATGAGGAT GACAATCTAATGGATGTCCTACAGCTGCTTGTTGCATTAATGTCAGAACACCCTAACTCTATGATTCCT GCTTTTGACCAAAGGAATGGGTTACGTGTTATCTACAAACTTCTGGCATCGAAAAGTGAAGGAATCAGG GTACAAGCTCTTAAGGCAATGGGTTATTTTTTAAAACATCTGGCCCCAAAGAGGAAAGCAGAAGTCATG CTTGGACATGGATTGTTTTCATTGCTAGCTGAAAGGCTCATGCTTCAGACAAATTTAATCACAATGACC ACATATAATGTGCTGTTTGAGATTCTTATAGAACAGATTGGTACTCAGGTGATACATAAACAGCATCCA GATCCTGATTCTTCAGTGAAGATACAAAACCCTCAGATACTAAAAGTAATTGCGACCCTACTTCGAAAT TCTCCCCAGTGCCCAGAGAGCATGGAGGTTCGCAGAGCCTTTCTTTCTGACATGATTAAACTTTTTAAT AACAGTAGAGAAAACAGGAGGAGCTTGCTACAATGCTCTGTGTGGCAAGAATGGATGCTTTCTCTCTGC TATTTTAATCCTAAGAATTCAGATGAGCAAAAGATAACAGAAATGGTATACGCCATATTCAGAATCCTG CTTTACCATGCAGTCAAATATGAGTGGGGTGGCTGGCGTGTATGGGTAGACACTTTATCAATCACTCAT TCAAAGGTCACTTTTGAAATACACAAAGAAAACCTTGCCAATATATTTAGGGAACAGCAAGGAAAAGTT GATGAAGAAATAGGGCTGTGTTCTTCAACTTCAGTTCAAGCAGCCTCTGGCATTAGAAGGGATATTAAT GTTTCAGTAGGATCCCAGCAACCAGATACGAAGGATTCTCCTGTCTGTCCTCATTTCACCACAAATGGT AATGAAAATTCAAGTATAGAGAAGACAAGTTCACTAGAATCTGCATCTAATATTGAACTGCAAACTACT AATACATCTTATGAAGAAATGAAAGCTGAGCAAGAAAATCAGGAGTTACCAGATGAAGGCACTTTGGAA GAAACACTGACAAATGAGACAAGGAATGCAGATGATTTAGAAGTATCTTCTGACATAATAGAAGCTGTG GCTATTTCCTCTAATTCTTTTATAACAACTGGCAAAGATTCAATGACTGTCAGTGAAGTAACTGCTTCT ATAAGTTCTCCTTCAGAAGAGGATGCCTCAGAGATGCCAGAATTCTTGGATAAATCTATAGTAGAGGAA GAGGAAGATGATGATTATGTGGAACTGAAAGTAGAAGGCAGTCCTACTGAGGAAGCTAATCTACCCACA GAGCTCCAAGATAACAGTTTGTCTCCAGCTGCATCTGAAGCCGGTGAAAAACTGGACATGTTTGGTAAT GATGACAAATTAATATTTCAAGAAGGAAAACCTGTTACTGAAAAGCAAACTGATACTGAAACTCAAGAT TCTAAAGATTCTGGAATTCAGACTATGACAGCATCAGGGTCTTCAGCTATGTCACCAGAAACTACTGTT TCCCAAATAGCTGTAGAATCAGACCTTGGTCAGATGCTGGAGGAAGGGAAGAAAGCAACTAACCTCACT AGAGAAACCAAATTAATTAATGATTGTCATGGTAGTGTCTCTGAGGCTTCTTCTGAGCAAAAGATTGCG AAGTTGGATGTTTCCAATGTTGCTACAGATACTGAGAGGCTGGAGTTGAAGGCCAGTCCCAACGTGGAA GCACCTCAACCTCATCGACATGTGCTTGAGATATCAAGGCAACATGAGCAGCCAGGGCAAGGAATAGCA CCAGATGCAGTTAATGGACAAAGGAGGGATTCCAGATCTACTGTGTTTCGTATTCCTGAGTTCAACTGG TCTCAGATGCATCAACGTTTGCTCACTGATCTATTATTTTCAATAGAAACAGATATACAGATGTGGAGA AGCCATTCAACAAAGACAGTTATGGACTTCGTGAATAGCAGTGATAATGTCATCTTTGTACACAACACA ATTCATCTCATCTCTCAAGTGATGGACAATATGGTCATGGCTTGTGGGGGTATACTGCCATTGCTTTCA GCTGCTACATCGGCTACACATGAACTGGAAAATATTGAACCTACTCAAGGCCTTTCAATAGAAGCCTCT GTGACATTTTTGCAGAGGCTAATTAGCCTTGTGGATGTGCTTATATTTGCAAGTTCTCTTGGCTTTACT GAAATTGAAGCTGAAAAAAGTATGTCATCTGGAGGAATTTTGCGGCAGTGTCTCCGACTAGTTTGTGCA GTCGCAGTAAGGAATTGCTTGGAGTGTCAACAGCATTCACAACTGAAAACTAGGGGAGATAAAGCCTTG AAACCAATGCATAGCCTTATTCCTTTAGGGAAATCTGCAGCGAAGAGCCCAGTGGACATTGTGACTGGC GGTATATCTCCAGTAAGAGATCTTGACAGGCTTCTACAGGACATGGATATTAATCGGCTTAGGGCAGTT GTTTTCAGAGACATAGAGGATAGCAAACAAGCTCAATTTTTAGCCTTGGCAGTAGTATACTTTATCTCT GTTCTTATGGTCTCCAAGTACAGAGACATTTTGGAACCCCAAAATGAAAGGCATAGCCAGTCATGTACA GAAACTGGCAGTGAAAATGAGAATGTATCACTCTCTGAAATCACACCAGCAGCATTCAGCACTTTAACT ACGGCATCAGTGGAAGAATCTGAAAGCACATCATCTGCTCGAAGGAGGGACTCAGGCATTGGGGAAGAA ACAGCCACTGGTTTAGGAAGCCATGTGGAAGTAACTCCTCACACAGCACCTCCTGGTGTCAGTGCAGGC CCAGATGCAATCAGCGAGGTGCTATCTACTCTTTCTTTAGAAGTCAATAAGTCTCCGGAAACCAAAAAT GATAGAGGAAATGACTTGGACACTAAGGCTACACCGTCAGTTTCAGTTTCAAAAAACGTCAATGTGAAA GACATTCTCCGAAGCTTGGTTAACATACCAGCAGATGGAGTCACAGTGGATCCTGCCCTTCTGCCACCA GCCTGCCTTGGAGCCCTTGGTGATCTATCTGTGGAACAACCCGTGCAGTTCAGATCTTTTGACAGAAGT GTCATTGTTGCAGCAAAAAAGTCAGCAGTCTCACCTTCCACCTTTAATACAAGCATACCTACCAATGCT GTCAGTGTGGTTTCCTCAGTAGATTCAGCCCAAGCCTCAGATATGGGAGGAGAATCACCAGGCAGTAGA TCATCTAATGCAAAATTGCCCTCAGTTCCAACAGTTGATTCAGTTTCACAAGATCCGGTTTCAAATATG AGTATTACAGAGAGGCTTGAACACGCTTTGGAAAAGGCAGCTCCTCTCCTTCGTGAGATTTTTGTGGAT TTTGCACCTTTTCTTTCTCGGACACTTTTGGGTAGCCATGGACAAGAACTGCTTATAGAAGGAACAAGT CTGGTTTGCATGAAGTCGAGTAGTTCAGTTGTGGAATTGGTTATGCTACTGTGTTCTCAGGAGTGGCAA AATTCTATTCAGAAGAATGCAGGCCTTGCTTTTATCGAACTTGTCAATGAAGGAAGGTTGCTTAGCCAG ACAATGAAGGATCATCTAGTAAGAGTAGCAAATGAAGCTGAATTTATCCTGAGCAGGCAGAGAGCAGAA GATATTCACAGACATGCGGAATTTGAGTCACTGTGTGCCCAGTATTCTGCAGACAAACGAGAAGATGAG AAGATGTGTGATCATTTGATAAGAGCAGCAAAATATCGTGACCACGTGACAGCAACTCAACTAATCCAG AAAATTATCAACATTCTCACAGACAAGCATGGAGCCTGGGGAAATTCTGCAGTGAGTCGTCCTCTTGAG TTCTGGCGCCTTGACTACTGGGAAGATGACTTGCGGCGCCGGCGACGATTTGTGCGTAACCCTCTAGGA TCGACACATCCTGAAGCGACACTAAAAACAGCCGTGGAACATGCCACAGATGAAGATATCCTTGCTAAA GGAAAACAGTCCATCAGGAGTCAGGCTTTAGGAAATCAGAACTCAGAAAACGAGATCCTCCTGGAAGGC GATGATGATACTCTGTCATCCGTGGATGAGAAAGATTTAGAGAATCTTGCCGGTCCTGTTAGCCTGAGC ACACCAGCTCAGCTTGTGGCCCCCTCTGTTGTAGTAAAGGGCACTCTTTCTGTCACCTCCTCCGAACTC TATTTTGAGGTGGATGAAGAGGATCCTAACTTCAAAAAAATCGACCCCAAGATCTTGGCATATACAGAA GGGCTGCATGGAAAATGGCTGTTCACAGAGATACGATCAATCTTTTCTCGTCGTTATCTTTTGCAAAAT ACAGCCCTGGAGATCTTTATGGCAAACAGAGTTGCTGTGATGTTCAACTTCCCAGACCCTGCAACAGTA AAGAAAGTGGTTAACTATCTACCTCGTGTTGGCGTTGGAACAAGTTTTGGATTGCCTCAAACCAGACGT ATTTCATTAGCTAGTCCACGTCAGCTTTTTAAGGCTTCTAATATGACCCAGCGATGGCAACACAGAGAG ATATCTAATTTTGAGTACTTGATGTTTCTCAACACGATAGCAGGACGGAGTTATAATGACTTAAATCAG TATCCAGTGTTTCCTTGGGTCATCACTAATTATGAATCAGAAGAACTGGATCTTACCTTGCCCACCAAC TTCAGAGATTTGTCCAAGCCAATAGGAGCTCTGAACCCAAAAAGAGCAGCATTCTTCGCTGAGCGTTAT GAATCATGGGAAGATGATCAAGTTCCAAAGTTTCACTATGGTACTCATTACTCAACTGCAAGTTTTGTT CTTGCATGGCTGCTAAGAATAGAACCCTTTACAACTTATTTCCTAAATTTGCAAGGAGGCAAATTTGAT CATGCAGATCGAACTTTTTCATCAATTTCCAGAGCTTGGCGAAACAGTCAGCGTGATACCTCTGATATT AAGGAGTTGATCCCTGAATTTTATTATCTCCCTGAGATGTTTGTCAACTTCAATAATTATAATCTTGGA GTGATGGATGATGGGACAGTAGTGTCTGATGTCGAACTTCCTCCTTGGGCCAAAACCTCAGAAGAATTT GTTCACATAAACAGATTGGCCCTGGAGAGTGAATTTGTTTCCTGCCAGCTTCACCAATGGATTGATCTC ATTTTTGGCTATAAACAGCAAGGACCAGAAGCTGTCCGAGCCCTCAATGTGTTCTATTACTTGACCTAT GAAGGAGCTGTCAATCTGAATTCAATAACTGATCCTGTGTTGAGAGAGGCTGTTGAAGCTCAAATCCGA AGTTTTGGACAGACTCCTTCTCAACTACTCATAGAGCCCCATCCTCCCAGAGGTTCTGCCATGCAAGTG AGTCCATTGATGTTCACAGACAAAGCCCAGCAGGATGTTATCATGGTCCTCAAGTTTCCCTCCAACTCC CCTGTTACTCACGTGGCAGCCAACACCCAGCCTGGTTTGGCAACTCCCGCTGTGATCACAGTCACTGCT AACAGGTTATTTGCGGTGAACAAATGGCACAACCTTCCTGCTCATCAAGGTGCTGTACAAGACCAGCCA TACCAGCTGCCAGTGGAAATCGATCCTCTCATAGCCAGCAATACAGGAATGCACAGGAGGCAAATCACT GACCTTTTAGACCAAAGTATTCAAGTGCATTCCCAGTGCTTTGTCATCACTTCAGACAACCGCTATATT CTCGTCTGTGGCTTCTGGGATAAAAGTTTCAGAGTCTATTCTACAGACACAGGAAGATTGATCCAAGTG GTGTTTGGCCATTGGGATGTCGTCACTTGCCTTGCTCGTTCTGAGTCATATATTGGGGGAAATTGCTAC ATTCTCTCAGGGTCACGTGATGCAACTCTTTTGCTGTGGTATTGGAATGGAAAATGCAGTGGGATTGGA GATAACCCAGGTGAGACTGCTGCTCCTCGGGCCATTTTGACCGGCCATGACTATGAGGTCACATGTGCT GCGGTGTGTGCGGAGCTAGGCCTGGTGTTGAGTGGTTCACAAGAAGGACCATGTCTCATACATTCCATG AATGGAGACTTGTTGAGGACCTTGGAGGGTCCTGAAAACTGCCTGAAACCAAAACTCATTCAGGCTTCA AGAGAGGGTCATTGTGTCATATTCTATGAAAACGGCCTCTTCTGTACATTCAGTGTGAATGGAAAACTC CAGGCCACGATGGAAACAGATGATAACATAAGAGCCATCCAGCTGAGCCGAGATGGGCAGTACCTGCTC ACAGGAGGAGACAGAGGAGTGGTCGTGGTCCGGCAGGTGTCGGACCTCAAGCAGCTCTTTGCCTATCCA GGATGTGACGCTGGAATCCGGGCCATGGCGCTGTCTTACGACCAGAGGTGCATCATTTCTGGCATGGCT TCAGGAAGCATTGTGCTATTTTACAACGACTTTAACCGGTGGCATCATGAATACCAAACCCGCTACTGA
Restriction Sites	SgfI-MluI
ACCN	NM_001199282
Insert Size	8556 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001199282.2
RefSeq Size	9919 bp
RefSeq ORF	8556 bp
Locus ID	987
UniProt ID	P50851
MW	317.7 kDa
Gene Summary	The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012] Transcript Variant: This variant (1) differs in the 5' UTR, lacks an alternate in-frame exon, and uses an alternate in-frame splice junction at the 3' end of an exon compared to variant 2. The resulting isoform (1) has the same N- and C-termini but is shorter compared to isoform 2.

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