MDM1 (NM_001205028) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC331634 representing NM_001205028. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGCCGGTGCGCTTCAAGGGGCTGAGTGAATACCAGAGGAACTTCCTGTGGAAAAAGTCTTATTTGTCC GAGTCTTGTAATTCCTCCGTGGGGCGAAAGTACCCATGGGCTGGACTTAGATCAGATCAATTAGGCATC ACGAAAGAGCCAAGTTTTATTTCAAAAAGAAGAGTCCCTTACCATGACCCACAGATTTCAAAATCTCTG GAGTGGAATGGAGCTATCTCAGAGAGCAATGTGGTTGCATCACCAGAACCAGAAGCCCCGGAAACACCA AAATCACAAGAAGCAGAACAAAAGGATGTTACTCAAGAAAGAGTTCACTCACTAGAAGCTTCCAGGGTT CCCAAAAGAACCAGATCTCACTCTGCAGACTCCAGAGCTGAAGGGGCTTCAGATGTGGAAAATAATGAG GGTGTAACAAACCATACACCAGTTAATGAAAATGTGGAACTGGAACATTCTACCAAGGTTCTTTCAGAA AATGTAGATAATGGGGTTTTCCACAATAAAAGCCAGTTTGTTCCACCATTCAAAGGTAACTCAGTCATC CATGAAACTGAATACAAAAGAAATTTCAAGGGTTTATCTCCAGTGAAAGAACCAAAATTAAGAAATGAT TTGAGAGAAAACAGAAATCTTGAAACAGTGTCTCCTGAAAGGAAGAGTAATAAAATAGACGATCGTTTA AAATTGGAAGCAGAGATGGAATTAAAAGACTTACACCAGCCTAAAAGGAAGCTTACTCCTTGGAAACAT CAAAGGCTTGGGAAGGTGAATTCCGAATATAGAGCAAAATTTCTGAGCCCAGCTCAGTATTTATATAAA GCTGGGGCTTGGACACATGTAAAGGGAAACATGCCAAATCAGGGTTCTCTAAATGCCATGTGGTATGCT GAGGTTAAAGAACTCCGAGAAAAGGCTGAGTTTTATAGGAAGCGAGTTCAGGGGACGCATTTTTCTCGG GACCATCTGAATCAGATTTTATCTGATAGCAACTGCTGTTGGGATGTCTCCTCAACCACAAGCTCAGAA GGAACCGTTAGTAGCAACATCAGAGCATTAGATCTTGCTGGAGATCCTACAAGCCATAAGACTTTGCAG AAATGTCCTTCTACAGAACCAGAAGAAAAAGGAAATATCGTGGAAGAACAGCCCCAGAAAAATACCACG GAGAAATTGGGTGTGTCAGCTCCCACCATACCCGTTAGAAGGCGGCTGGCTTGGGATACAGAGAACACA AGTGAAGACGTACAGAAACAGCCCGGGGAGAAAGAGGAGGAGGACGACAATGAAGAGGAAGGGGACAGG AAAACGGGCAAGCAGGCTTTTATGGGAGAGCAAGAGAAGTTGGATGTACGTGAGAAATCTAAGGCAGAT AAGATGAAAGAAGGGTCAGATTCTTCTGTATCCTCAGAAAAAGGAGGCCGGCTTCCTACTCCCAAGCTG AGAGAACTTGGTGGAATCCAGAGGACTCATCATGATCTCACTACTCCAGCTGTTGGTGGTGCTGTTTTA GTGTCTCCATCTAAGATGAAGCCTCCAGCCCCAGAACAGAGGAAAAGAATGACCTCTCAGGATTGTTTA GAAACTTCAAAGAATGATTTTACTAAGAAAGAAAGTCGTGCTGTATCCCTACTGACTTCTCCAGCTGCT GGTATAAAAACAGTTGATCCTCTGCCTTTGCGGGAAGATTCTGAAGACAATATCCACAAATTTGCTGAG GCAACTCTTCCAGTTTCAAAAATTCCAAAATACCCAACAAATCCCCCTGGACAGTTGCCTTCTCCACCA CATGTTCCATCCTACTGGCATCCCTCTCGACGAATTCAGGGCTCTCTTAGAGATCCAGAGTTTCAGCAC AATGTGGGAAAAGCAAGGATGAACAATTTGCAGTTACCTCAACATGAAGCCTTTAATGATGAAGATGAG GACAGATTGTCTGAGATTTCTGCTCGCTCTGCAGCTTCTAGTCTCCGGGCTTTTCAAACTCTGGCACGA GCTAAGAAAAGGAAGGAGAATTTCTGGGGTAAAACATAA
Restriction Sites	SgfI-MluI
ACCN	NM_001205028
Insert Size	2040 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001205028.1
RefSeq Size	2888 bp
RefSeq ORF	2040 bp
Locus ID	56890
UniProt ID	Q8TC05
Protein Families	Druggable Genome
MW	76.7 kDa
Gene Summary	This gene encodes a microtubule-binding nuclear protein that localizes to the centrioles of dividing cells and differentiating multiciliated cells and negatively regulates centriole duplication. The encoded protein is closely associated with the centriole barrel, and resides in the centriole lumen. Naturally-occurring mutations in the orthologous mouse gene are associated with age-related retinal degeneration. [provided by RefSeq, Feb 2019] Transcript Variant: This variant (4) lacks an in-frame coding exon in the 5' region and contains a novel exon in the mid-region compared to variant 1. This results in a shorter isoform (4) compared to isoform 1.

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