PITRM1 (NM_001242309) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	MP1; PreP
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC331783 representing NM_001242309. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGCGCAATGTGGCGCTGCGGCGGGCGGCAGGGCCTGTGTGTGCTGAGGCGGCTGAGCGGCGGGTGACA TCTGTTCCCGAGCTGTTCCTGACTGCAGTGAAGCTCACCCATGATGACACAGGAGCCAGGTATTTACAC CTGGCCAGAGAAGACACGAATAATCTGTTCAGCGTGCAGTTCCGTACTACTCCCATGGACAGTACTGGT GTTCCTCACATTCTTGAGCATACCGTCCTTTGTGGGTCTCAGAAATATCCGTGCAGAGACCCTTTCTTC AAAATGTTGAACCGGTCCCTCTCCACGTTCATGAACGCCTTCACAGCTAGTGATTATACTCTGTATCCA TTTTCCACACAAAATCCCAAGGACTTTCAGAATCTCCTCTCGGTGTATTTGGATGCCACCTTTTTCCCA TGTTTACGCGAGCTGGATTTCTGGCAGGAAGGATGGCGGCTGGAACATGAGAATCCGAGCGACCCCCAG ACGCCCTTGGTCTTTAAAGGAGTCGTCTTTAATGAGATGAAGGGAGCGTTTACAGACAATGAGAGGATA TTCTCCCAGCACCTTCAGAACAGACTTCTTCCTGACCACACGTACTCAGTGGTCTCCGGGGGTGACCCA CTGTGCATCCCGGAGCTTACATGGGAGCAGCTTAAGCAGTTTCATGCCACTCACTATCACCCAAGCAAT GCTAGGTTCTTCACGTACGGTAATTTTCCATTAGAACAGCATCTGAAACAAATTCACGAGGAAGCACTG AGCAAATTCCAGAAAATTGAACCAAGCACCGTGGTGCCAGCTCAGACACCCTGGGACAAGCCTAGGGAA TTCCAGATAACATGTGGCCCGGATTCATTTGCTACAGATCCCTCTAAACAAACAACCATCAGCGTTAGC TTCCTCTTACCGGACATCACCGACACATTTGAAGCCTTCACATTAAGTCTTCTGTCTTCACTCTTGACT TCTGGGCCCAATTCTCCCTTTTACAAAGCCTTGATTGAATCTGGCCTTGGCACAGACTTTTCTCCTGAT GTTGGATATAATGGCTACACGAGGGAGGCCTACTTTAGTGTCGGCCTCCAAGGGATTGCGGAGAAAGAC ATTGAGACCGTCAGAAGCCTCATAGACAGAACGATTGATGAAGTAGTTGAGAAAGGATTTGAAGATGAT CGAATTGAGGCTTTACTTCATAAAATTGAAATACAGATGAAACATCAGTCTACCAGCTTTGGGCTGATG CTGACATCATACATAGCTTCTTGCTGGAACCATGATGGGGACCCTGTGGAGCTCTTGAAGTTGGGAAAT CAGTTAGCTAAATTCAGACAGTGCCTGCAGGAAAATCCAAAATTTTTGCAAGAAAAAGTAAAACAGTAT TTTAAGAATAACCAGCATAAGCTGACTTTATCGATGAGGCCAGATGACAAGTATCACGAGAAGCAGGCA CAGGTGGAAGCCACGAAGCTCAAGCAGAAGGTCGAGGCTCTGTCCCCCGGAGACAGGCAGCAGATCTAC GAGAAAGGTCTAGAATTACGGAGTCAACAAAGCAAACCTCAAGATGCCTCTTGTCTGCCAGCGTTGAAA GTTTCCGATATTGAACCCACCATACCTGTCACAGAGTTGGACGTGGTCCTGACAGCTGGAGATATCCCT GTTCAGTACTGCGCCCAGCCCACCAATGGCATGGTGTATTTCCGGGCCTTCTCCAGCCTGAACACACTC CCCGAGGAGCTGAGGCCCTATGTGCCCCTCTTCTGCAGCGTCCTCACCAACCCGTGCTTTGAAGAAGAG GAGCACTTCAAGGTGCTGGTGAAGATGACCGCCCAGGAGCTCGCCAATGGAATTCCTGACTCTGGGCAC CTGTACGCATCCATCAGGGCAGGCCGGACCCTCACGCCCGCAGGGGACCTGCAGGAGACCTTCAGCGGG ATGGATCAGGTGCGGCTGATGAAGAGGATTGCAGAAATGACAGATATCAAACCCATCCTGAGGAAGCTC CCGCGTATCAAGAAACACTTGTTAAATGGTGATAATATGAGGTGTTCAGTGAATGCGACTCCTCAGCAG ATGCCTCAGACAGAAAAAGCGGTCGAAGACTTCCTTAGAAGCATCGGTCGGAGTAAAAAGGAACGGAGG CCTGTGCGCCCACACACGGTCGAGAAACCTGTGCCCAGCAGCTCTGGTGGAGATGCCCACGTTCCCCAT GGCTCCCAGGTCATTAGGAAGCTGGTCATGGAACCCACCTTCAAGCCCTGGCAGATGAAGACTCACTTC CTGATGCCCTTCCCGGTGAATTACGTGGGTGAATGCATCCGAACTGTCCCCTACACGGACCCAGATCAT GCCAGTCTTAAAATCCTTGCACGTTTGATGACTGCCAAATTCTTGCATACAGAAATTCGAGAAAAAGGC GGTGCTTATGGTGGAGGCGCAAAACTCAGCCACAATGGGATTTTCACCCTTTACTCTTACAGGGACCCA AATACAATAGAGACGCTCCAGTCTTTTGGGAAGGCTGTCGACTGGGCTAAGTCTGGAAAATTCACACAG CAAGACATCGACGAAGCCAAACTTTCTGTCTTCTCAACCGTAGATGCTCCTGTCGCTCCTTCAGACAAA GGAATGGACCACTTCTTGTACGGCCTCTCGGATGAGATGAAGCAGGCCCACAGAGAGCAGCTCTTTGCT GTCAGCCACGACAAGCTCCTGGCCGTGAGCGATAGATACCTCGGCACTGGGAAGAGCACACACGGCCTG GCCATCCTCGGACCCGAGAACCCGAAAATTGCCAAGGACCCATCCTGGATCATCCAATGA
Restriction Sites	SgfI-MluI
ACCN	NM_001242309
Insert Size	2820 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001242309.1
RefSeq Size	3198 bp
RefSeq ORF	2820 bp
Locus ID	10531
UniProt ID	Q5JRX3
Protein Families	Druggable Genome, Protease
MW	106.1 kDa
Gene Summary	The protein encoded by this gene is an ATP-dependent metalloprotease that degrades post-cleavage mitochondrial transit peptides. The encoded protein binds zinc and can also degrade amyloid beta A4 protein, suggesting a possible role in Alzheimer's disease. [provided by RefSeq, Dec 2016] Transcript Variant: This variant (3) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. These differences cause translation initiation at an alternate AUG and results an isoform (3) with a distinct N-terminus, compared to isoform 1. The encoded protein likely does not localize to the mitochondrion. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.