ARNTL2 (NM_001248002) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	bHLHe6; BMAL2; CLIF; MOP9; PASD9
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC332125 representing NM_001248002. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGGCGGCGGAAGAGGAGGCTGCGGCGGGAGGTAAAGTGTTGAGAGAGGAGAACCAGTGCATTGCTCCT GTGGTTTCCAGCCGCGTGAGTCCAGGGACAAGACCAACAGCTATGGGGTCTTTCAGCTCACACATGACA GAGTTTCCACGAAAACGCAAAGGAAGTGATTCAGACCCATCCCAGTCAGGAATCATGACAGAAAAAGTG GTGGAAAAGCTTTCTCAGAATCCCCTTACCTATCTTCTTTCAACAAGGATAGAAATATCAGCCTCCAGT GGCAGCAGAGAAGCTCATAGCCAAACTGAAAAGCGGAGGAGAGATAAAATGAATAACCTGATTGAAGAA CTGTCTGCAATGATCCCTCAGTGCAACCCCATGGCGCGTAAACTGGACAAACTTACAGTTTTAAGAATG GCTGTTCAACACTTGAGATCTTTAAAAGGCTTGACAAATTCTTATGTGGGAAGTAATTATAGACCATCA TTTCTTCAGGATAATGAGCTCAGACATTTAATCCTTAAGACTGCAGAAGGCTTCTTATTTGTGGTTGGA TGTGAAAGAGGAAAAATTCTCTTCGTTTCTAAGTCAGTCTCCAAAATACTTAATTATGATCAGGCTAGT TTGACTGGACAAAGCTTATTTGACTTCTTACATCCAAAAGATGTTGCCAAAGTAAAGGAACAACTTTCT TCTTTTGATATTTCACCAAGAGAAAAGCTAATAGATGCCAAAACTGGTTTGCAAGTTCACAGTAATCTC CACGCTGGAAGGACACGTGTGTATTCTGGCTCAAGACGATCTTTTTTCTGTCGGATAAAGAGTTGTAAA ATCTCTGTCAAAGAAGAGCATGGATGCTTACCCAACTCAAAGAAGAAAGAGCACAGAAAATTCTATACT ATCCATTGCACTGGTTACTTGAGAAGCTGGCCTCCAAATATTGTTGGAATGGAAGAAGAAAGGAACAGT AAGAAAGACAACAGTAATTTTACCTGCCTTGTGGCCATTGGAAGATTACAGCCATATATTGTTCCACAG AACAGTGGAGAGATTAATGTGAAACCAACTGAATTTATAACCCGGTTTGCAGTGAATGGAAAATTTGTC TATGTAGATCAAAGGGCAACAGCGATTTTAGGATATCTGCCTCAGGAACTTTTGGGAACTTCTTGTTAT GAATATTTTCATCAAGATGACCACAATAATTTGACTGACAAGCACAAAGCAGTTCTACAGAGTAAGGAG AAAATACTTACAGATTCCTACAAATTCAGAGCAAAAGATGGCTCTTTTGTAACTTTAAAAAGCCAATGG TTTAGTTTCACAAATCCTTGGACAAAAGAACTGGAATATATTGTATCTGTCAACACTTTAGTTTTGGGA CATAGTGAGCCTGGAGAAGCATCATTTTTACCTTGTAGCTCTCAATCATCAGAAGAATCCTCTAGACAG TCCTGTATGAGTGTACCTGGAATGTCTACTGGAACAGTACTTGGTGCTGGTAGTATTGGAACAGATATT GCAAATGAAATTCTGGATTTACAGAGGTTACAGTCTTCTTCATACCTTGATGATTCGAGTCCAACAGGT TTAATGAAAGATACTCATACTGTAAACTGCAGGAGTATGTCAAATAAGGAGTTGTTTCCACCAAGTCCT TCTGAAATGGGGGAGCTAGAGGCTACCAGGCAAAACCAGAGTACTGTTGCTGTCCACAGCCATGAGCCA CTCCTCAGTGATGGTGCACAGTTGGATTTCGATGCCCTATGTGACAATGATGACACAGCCATGGCTGCA TTTATGAATTACTTAGAAGCAGAGGGGGGCCTGGGAGACCCTGGGGACTTCAGTGACATCCAGTGGACC CTCTAG
Restriction Sites	SgfI-MluI
ACCN	NM_001248002
Insert Size	1869 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001248002.1
RefSeq Size	7369 bp
RefSeq ORF	1869 bp
Locus ID	56938
UniProt ID	Q8WYA1
Protein Families	Druggable Genome, Transcription Factors
MW	69.2 kDa
Gene Summary	This gene encodes a basic helix-loop-helix transcription factor belonging to the PAS (PER, ARNT, SIM) superfamily. The PAS proteins play important roles in adaptation to low atmospheric and cellular oxygen levels, exposure to certain environmental pollutants, and diurnal oscillations in light and temperature. This protein forms a transcriptionally active heterodimer with the circadian CLOCK protein, the structurally related MOP4, and hypoxia-inducible factors, such as HIF1alpha. Consistent with its role as a biologically relevant partner of circadian and hypoxia factors, this protein is coexpressed in regions of the brain such as the thalamus, hypothalamus, and amygdala. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011] Transcript Variant: This variant (2) lacks an in-frame coding exon compared to variant 1. This results in a shorter isoform (2) missing an internal protein segment compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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