NBPF3 (NM_001256417) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	AE2
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC332376 representing NM_001256417. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGCCACTGACTCCCACTGTCCAGGGCTTCCAGTGGACTCTCCGAGGCCCTGATGTAGAAACTTCCCCA TTCGGTGCACCAAGAGCAGCCTCACATGGTGTGGGCCGACATCAAGAGCTGCGAGATCCAACAGACTAT GAAGACTGCAAAGACCTCATAAAATCTATGCTGAGGGATGAGCGGCTGCTCACAGAAGAGAAGCTTGCA GAGGAGCTCGGGCAAGCTGAGGAGCTCAGGCAATATAAAGTCCTGGTTCACTCTCAGGAACGAGAGCTG ACCCAGTTAAGGGAGAAGTTACAGGAAGGGAGAGATGCCTCCCGCTCATTGAATCAGCATCTCCAGGCC CTCCTCACTCCGGATGAGCCGGACAACTCCCAGGGACGGGACCTCCGAGAACAGCTGGCTGAGGGATGT AGGCTGGCACAGCACCTCGTCCAAAAGCTCAGCCCAGAAAATGATGACGATGAGGATGAAGATGTTAAA GTTGAGGAGGCTGAGAAAGTACAGGAATTATATGCCCCCAGGGAGGTGCAGAAGGCTGAAGAAAAGGAA GTCCCTGAGGACTCACTGGAGGAGTGTGCCATCACTTGTTCAAATAGCCACCACCCTTGTGAGTCCAAC CAGCCTTACGGGAACACCAGAATCACATTTGAGGAAGACCAAGTCGACTCAACTCTCATTGACTCATCC TCTCATGATGAATGGTTGGATGCTGTATGCATTATCCCAGAAAATGAAAGTGATCATGAGCAAGAGGAA GAAAAAGGGCCAGTGTCTCCCAGGAATCTGCAGGAGTCTGAAGAGGAGGAAGCCCCCCAGGAGTCCTGG GATGAAGGTGATTGGACTCTCTCAATTCCTCCTGACATGTCTGCCTCATACCAGTCTGACAGGAGCACC TTTCACTCAGTAGAGGAACAGCAAGTCGGCTTGGCTCTTGACATAGGCAGACATTGGTGTGATCAAGTG AAAAAGGAGGACCAAGAGGCCACAAGTCCCAGGCTCAGCAGGGAGCTGCTGGATGAGAAAGAGCCTGAA GTCTTGCAGGACTCACTGGATAGATTTTATTCAACTCCTTTTGAGTACCTGGAACTGCCTGACTTATGC CAGCCCTACAGAAGTGACTTTTACTCATTGCAGGAACAACACCTTGGCTTGGCTCTTGACTTGGACAGA ATGAAAAAGGACCAAGAAGAGGAAGAAGACCAAGGCCCACCATGCCCCAGGCTCAGCAGAGAGCTGCCG GAGGTAGTAGAGCCTGAGGACTTGCAGGACTCACTGGATAGATGGTATTCGACTCCTTTCAGTTATCCA GAACTGCCTGATTCATGCCAGCCCTACGGAAGTTGCTTTTACTCATTGGAGGAAGAACACGTTGGCTTT TCTCTTGACGTGGATGAAATTGAAAAGTACCAAGAAGGGGAAGAAGATCAAAAGCCACCATGCCCCAGG CTCAACGAGGTGCTGATGGAAGCAGAAGAGCCTGAAGTCTTGCAGGACTCACTGGATAGATGTTATTCG ACTACTTCAACTTACTTTCAACTACATGCCTCATTCCAGCAGTATAGAAGTGCCTTTTACTCATTTGAG GAACAGGACGTCAGCTTGGCCCTTGACGTGGACAATAGGTTTTTTACTTTGACAGTGATAAGGCACCAC CTGGCCTTCCAGATGGGAGTCATATTCCCACACTAA
Restriction Sites	SgfI-MluI
ACCN	NM_001256417
Insert Size	1692 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001256417.2
RefSeq Size	3621 bp
RefSeq ORF	1692 bp
Locus ID	84224
UniProt ID	Q9H094
MW	65.1 kDa
Gene Summary	This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. DUF1220 copy number variations in human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, cognitive disability, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes. [provided by RefSeq, Feb 2013] Transcript Variant: This variant (3) lacks an alternate exon in the coding region, compared to variant 1. The resulting protein (isoform 3) is shorter, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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