SLC4A7 (NM_001258380) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	NBC2; NBC3; NBCN1; SBC2; SLC4A6
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC332683 representing NM_001258380. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGGAAAGATTTCGTCTGGAGAAGAAGTTACCTGGTCCTGATGAAGAAGCTGTTGTGGATCTTGGCAAA ACTAGCTCAACTGTGAACACCAAGTTTGAAAAAGAAGAACTAGAAAGTCATAGAGCTGTATATATTGGT GTTCACGTCCCGTTTAGTAAAGAGAGTCGTCGGCGTCATAGGCATCGCGGACACAAACATCACCACCGG AGAAGAAAAGATAAAGAATCAGATAAAGAAGATGGACGGGAATCTCCTTCTTATGATACACCATCCCAG AGAGTTCAGTTTATCCTTGGTACTGAAGATGATGATGAAGAACATATTCCCCATGATCTCTTCACGGAA ATGGATGAACTGTGTTACAGAGATGGAGAAGAATATGAATGGAAAGAAACTGCTAGATGGCTGAAATTT GAAGAGGATGTTGAAGATGGCGGTGACCGATGGAGTAAACCTTATGTGGCAACTCTCTCTTTGCACAGT CTTTTTGAACTAAGGAGTTGCATCCTCAATGGAACAGTCATGCTGGATATGAGAGCAAGCACTCTAGAT GAAATAGCAGATATGGTATTAGACAACATGATAGCTTCTGGCCAATTAGACGAGTCCATACGAGAGAAT GTCAGAGAAGCTCTTCTGAAGAGACATCATCATCAGAATGAGAAAAGATTCACCAGTCGGATTCCTCTT GTTCGATCTTTTGCAGATATAGGCAAGAAACATTCTGACCCTCACTTGCTTGAAAGGAATGGTATTTTG GCCTCTCCCCAGTCTGCTCCTGGAAACTTGGACAATAGTAAAAGTGGAGAAATTAAAGGTAATGGAAGT GGTGGAAGCAGAGAAAATAGTACTGTTGACTTCAGCAAGGTTGATATGAATTTCATGAGAAAAATTCCT ACGGGTGCTGAGGCATCCAACGTCCTGGTGGGCGAAGTAGACTTTTTGGAAAGGCCAATAATTGCATTT GTGAGACTGGCTCCTGCTGTCCTCCTTACAGGGTTGACTGAGGTCCCTGTTCCAACCAGGTTTTTGTTT TTGTTATTGGGTCCAGCGGGCAAGGCACCACAGTACCATGAAATTGGACGATCAATAGCCACTCTCATG ACAGATGAGATTTTCCATGATGTAGCTTATAAAGCAAAAGACAGAAATGACCTCTTATCTGGAATTGAT GAATTTTTAGATCAAGTAACTGTCCTACCTCCAGGAGAGTGGGATCCTTCTATACGCATAGAACCACCA AAAAGTGTCCCTTCTCAGGAAAAGAGAAAGATTCCTGTGTTTCACAATGGATCTACCCCCACACTGGGT GAGACTCCTAAAGAGGCCGCTCATCATGCTGGGCCTGAGCTACAGAGGACTGGACGGCTTTTTGGTGGT TTGATACTTGACATCAAAAGGAAAGCACCTTTTTTCTTGAGTGACTTCAAGGATGCATTAAGCCTGCAG TGCCTGGCCTCGATTCTTTTCCTATACTGTGCCTGTATGTCTCCTGTAATCACTTTTGGAGGGCTGCTT GGAGAAGCTACAGAAGGCAGAATAAGTGCAATAGAGTCTCTTTTTGGAGCATCATTAACTGGGATTGCC TATTCATTGTTTGCTGGGCAACCTCTAACAATATTGGGGAGCACAGGTCCAGTTCTAGTGTTTGAAAAA ATTTTATATAAATTCTGCAGAGATTATCAACTTTCTTATCTGTCTTTAAGAACCAGTATTGGTCTGTGG ACTTCTTTTTTGTGCATTGTTTTGGTTGCAACAGATGCAAGCAGCCTTGTGTGTTATATTACTCGATTT ACAGAAGAGGCTTTTGCAGCCCTTATTTGCATCATATTCATCTACGAGGCTTTGGAGAAGCTCTTTGAT TTAGGAGAAACATATGCATTTAATATGCACAACAACTTAGATAAACTGACCAGCTACTCATGTGTATGT ACTGAACCTCCAAACCCCAGCAATGAAACTCTAGCACAATGGAAGAAAGATAATATAACAGCACACAAT ATTTCCTGGAGAAATCTTACTGTTTCTGAATGTAAAAAACTTCGTGGTGTATTCTTGGGGTCAGCTTGT GGTCATCATGGACCTTATATTCCAGATGTGCTCTTTTGGTGTGTCATCTTGTTTTTCACAACATTTTTT CTGTCTTCATTCCTCAAGCAATTTAAGACCAAGCGTTACTTTCCTACCAAGGTGCGATCGACAATCAGT GATTTTGCTGTATTTCTCACAATAGTAATAATGGTTACAATTGACTACCTTGTAGGAGTTCCATCTCCT AAACTTCATGTTCCTGAAAAATTTGAGCCTACTCATCCAGAGAGAGGGTGGATCATAAGCCCACTGGGA GATAATCCTTGGTGGACCTTATTAATAGCTGCTATTCCTGCTTTGCTTTGTACCATTCTCATCTTTATG GATCAACAAATCACAGCTGTAATTATAAACAGAAAGGAACACAAATTGAAGAAAGGAGCTGGCTATCAC CTTGATTTGCTCATGGTTGGCGTTATGTTGGGAGTTTGCTCTGTCATGGGACTTCCATGGTTTGTGGCT GCAACAGTGTTGTCAATAAGTCATGTCAACAGCTTAAAAGTTGAATCTGAATGTTCTGCTCCAGGGGAA CAACCCAAGTTTTTGGGAATTCGTGAACAGCGGGTTACAGGGCTAATGATTTTTATTCTAATGGGCCTC TCTGTGTTCATGACTTCAGTCCTAAAGTTTATTCCAATGCCTGTTCTGTATGGTGTTTTCCTTTATATG GGAGTTTCCTCATTAAAAGGAATCCAGTTATTTGACCGTATAAAATTATTTGGAATGCCTGCTAAGCAT CAGCCTGATTTGATATACCTCCGTTATGTGCCGCTCTGGAAGGTCCATATTTTCACAGTCATTCAGCTT ACTTGTTTGGTCCTTTTATGGGTGATAAAAGTTTCAGCTGCTGCAGTGGTTTTTCCCATGATGGTTCTT GCATTAGTGTTTGTGCGCAAACTCATGGACCTGTGTTTCACGAAGAGAGAACTTAGTTGGCTTGATGAT CTTATGCCAGAAAGTAAGAAAAAGAAAGAAGATGACAAAAAGAAAAAAGAGAAAGAGGAAGCTGAACGG ATGCTTCAAGATGATGATGATACTGTGCACCTTCCATTTGAAGGGGGAAGTCTCTTGCAAATTCCAGTC AAGGCCCTAAAATATAGTCCTGATAAACCTGTGAGTGTGAAAATAAGTTTTGAAGATGAACCAAGAAAG AAATACGTGGATGCTGAAACTTCATTATAG
Restriction Sites	SgfI-MluI
ACCN	NM_001258380
Insert Size	3273 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001258380.1
RefSeq Size	7395 bp
RefSeq ORF	3273 bp
Locus ID	9497
UniProt ID	Q9Y6M7
Protein Families	Druggable Genome, Transmembrane
MW	123.1 kDa
Gene Summary	This locus encodes a sodium bicarbonate cotransporter. The encoded transmembrane protein appears to transport sodium and bicarbonate ions in a 1:1 ratio, and is thus considered an electroneutral cotransporter. The encoded protein likely plays a critical role in regulation of intracellular pH involved in visual and auditory sensory transmission. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Apr 2012] Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. This results in a shorter protein (isoform c), compared to isoform a.

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