RTN3 (NM_001265590) Human Untagged Clone
CAT#: SC332811
RTN3 (untagged) - Homo sapiens reticulon 3 (RTN3), transcript variant 6
CNY 8,840.00
货期*
5周
规格
Product images
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经常一起买 (4)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | ASYIP; HAP; NSPL2; NSPLII; RTN3-A1 |
Vector | pCMV6-Entry |
Sequence Data |
>SC332811 representing NM_001265590.
Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGGCGGAGCCGTCGGCGGCCACTCAGTCCCATTCCATCTCCTCGTCGTCCTTCGGAGCCGAGCCGTCC GCGCCCGGCGGCGGCGGGAGCCCAGGAGCCTGCCCCGCCCTGGGGACGAAGAGCTGCAGCTCCTCCTGT GCGGCCAGTTTCCCAGAGCATCCTGCTTTTCTCTCAAAGAAAATTGGTCAAGTGGAAGAGCAAATAGAT AAAGAGACCAAGAACCCAAATGGGGTATCAAGTAGGGAGGCTAAAACTGCATTGGATGCTGATGACAGA TTCACTTTGCTGACAGCCCAGAAACCACCTACTGAGTACTCTAAGGTAGAAGGCATTTATACATATTCT TTGTCTCCATCCAAAGTTTCAGGAGATGATGTTATTGAAAAGGATTCCCCTGAATCACCATTTGAAGTA ATTATTGACAAAGCAGCATTTGACAAAGAATTTAAAGACTCATATAAGGAGAGCACAGATGATTTTGGT AGCTGGTCTGTGCACACTGATAAAGAATCATCCGAAGACATTTCAGAGACTAATGACAAGCTTTTTCCA CTGAGAAATAAAGAGGCAGGACGTTACCCAATGTCTGCATTGCTCAGTAGGCAGTTTTCACACACAAAT GCAGCACTGGAAGAGGTGTCCAGATGCGTGAATGATATGCATAACTTTACTAACGAAATACTGACTTGG GATCTGGTTCCCCAAGTGAAACAACAGACCGATAAATCTTCTGACTGCATCACAAAAACTACAGGACTT GACATGAGTGAATATAATTCAGAAATTCCAGTTGTAAATCTTAAAACTAGCACTCATCAGAAAACTCCT GTATGTTCTATTGATGGGAGCACTCCCATCACTAAATCAACAGGTGATTGGGCAGAAGCATCTCTCCAG CAAGAAAATGCTATTACTGGAAAACCTGTACCTGACTCTTTGAATTCCACAAAAGAATTCAGTATCAAA GGTGTGCAAGGCAATATGCAGAAACAGGATGACACACTTGCAGAATTACCTGGATCTCCACCTGAGAAA TGTGACTCTTTGGGTTCTGGAGTGGCCACAGTGAAAGTGGTTTTACCTGATGACCACCTGAAAGATGAA ATGGACTGGCAGAGCTCTGCATTGGGAGAAATCACAGAAGCTGATAGTTCTGGTGAGTCTGATGACACA GTAATAGAGGACATCACAGCAGATACATCATTTGAAAATAACAAAATTCAGGCTGAAAAACCTGTTTCC ATTCCAAGTGCTGTTGTAAAAACAGGTGAAAGAGAAATCAAAGAGATTCCCAGTTGTGAGAGAGAAGAA AAAACATCTAAAAACTTTGAAGAATTGGTCAGTGACTCTGAGCTGCATCAAGATCAGCCTGATATTCTT GGAAGGAGTCCAGCTAGTGAGGCAGCATGTTCAAAAGTACCCGATACGAATGTCTCCTTAGAAGATGTG AGTGAAGTTGCTCCTGAAAAGCCTATTACTACTGAGAACCCCAAACTTCCTTCAACAGTGTCTCCAAAT GTTTTTAATGAGACAGAATTCTCATTAAATGTGACAACATCTGCCTATTTGGAGTCATTACATGGGAAA AATGTTAAACATATAGATGATTCCTCCCCAGAGGACCTGATAGCAGCCTTTACAGAAACCAGAGATAAA GGAATAGTAGATAGTGAAAGAAATGCTTTTAAAGCAATATCAGAGAAGATGACAGACTTTAAAACAACT CCTCCTGTAGAAGTCTTACATGAAAATGAGTCCGGTGGTTCTGAAATTAAAGACATTGGAAGCAAATAC AGTGAACAAAGCAAAGAAACAAATGGAAGTGAGCCTCTAGGTGTTTTCCCTACCCAAGGTACTCCAGTA GCATCTCTTGACTTAGAACAAGAACAGCTCACAATTAAGGCTCTTAAAGAATTAGGTGAAAGACAGGTT GAGAAGTCAACTTCTGCACAGCGTGACGCAGAATTGCCTTCTGAAGAAGTACTGAAGCAAACTTTCACA TTTGCTCCAGAATCTTGGCCACAGAGATCATATGACATCCTAGAACGTAATGTCAAGAATGGATCTGAT CTTGGGATTTCCCAGAAGCCCATCACTATCAGAGAAACTACTAGGGTAGATGCTGTTTCCAGCCTTAGC AAGACTGAATTGGTAAAAAAGCATGTCCTAGCAAGACTTCTGACAGACTTCTCAGTGCACGATCTGATT TTCTGGAGAGATGTGAAGAAGACTGGGTTTGTCTTTGGCACCACGCTGATCATGCTGCTTTCCCTGGCA GCTTTCAGTGTCATCAGTGTGGTTTCTTACCTCATCCTGGCTCTTCTCTCTGTCACCATCAGCTTCAGG ATCTACAAGTCCGTCATCCAAGCTGTACAGAAGTCAGAAGAAGGCCATCCATTCAAAGCCTACCTGGAC GTAGACATTACTCTGTCCTCAGAAGCTTTCCATAATTACATGAATGCTGCCATGGTGCACATCAACAGG GCCCTGAAACTCATTATTCGTCTCTTTCTGGTAGAAGATCTGGTTGACTCCTTGAAGCTGGCTGTCTTC ATGTGGCTGATGACCTATGTTGGTGCTGTTTTTAACGGAATCACCCTTCTAATTCTTGCTGAACTGCTC ATTTTCAGTGTCCCGATTGTCTATGAGAAGTACAAGACCCAGATTGATCACTATGTTGGCATCGCCCGA GATCAGACCAAGTCAATTGTTGAAAAGATCCAAGCAAAACTCCCTGGAATCGCCAAAAAAAAGGCAGAA TAA |
Restriction Sites | SgfI-MluI |
ACCN | NM_001265590 |
Insert Size | 2763 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001265590.1 |
RefSeq Size | 4640 bp |
RefSeq ORF | 2763 bp |
Locus ID | 10313 |
UniProt ID | O95197 |
Protein Families | Transmembrane |
MW | 100.8 kDa |
Gene Summary | This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12. [provided by RefSeq, May 2012] Transcript Variant: This variant (6) includes an alternate exon in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (f) is longer than isoform a. |
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