CDK5RAP2 (NM_001272039) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	C48; Cep215; MCPH3
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC333191 representing NM_001272039. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGATGGACTTGGTGTTGGAAGAGGACGTCACCGTCCCTGGGACGCTCAGCGGCTGCAGTGGCCTTGTT CCCAGTGTACCAGATGACCTGGATGGCATCAACCCCAATGCTGGGTTGGGAAATGGTCTGCTCCCAAAT GTGTCAGAAGAAACAGTGTCTCCCACCAGAGCACGGAACATGAAGGACTTTGAAAATCAAATCACTGAA TTGAAGAAAGAAAACTTTAACCTAAAGCTCCGCATCTATTTCCTTGAGGAAAGAATGCAACAGGAATTT CATGGCCCCACTGAACATATCTACAAAACTAACATTGAGCTCAAGGTGGAAGTAGAAAGTCTGAAGCGG GAACTCCAGGAGAGAGAGCAGCTGCTCATCAAAGCCTCCAAAGCAGTTGAGAGCTTAGCTGAAGCAGGT GGCTCTGAAATCCAGCGGGTGAAAGAAGATGCTCGAAAGAAGGTGCAGCAGGTGGAAGATCTCCTAACT AAAAGAATACTCCTTTTGGAAAAGGATGTGACAGCCGCCCAGGCAGAACTGGAAAAGGCCTTTGCAGGG ACAGAGACGGAGAAGGCTCTTCGGTTGCGTTTGGAAAGCAAGCTTTCAGAGATGAAGAAGATGCACGAG GGGGACTTGGCGATGGCTCTGGTCCTGGATGAGAAAGACAGACTGATTGAGGAGTTGAAGCTGTCTTTG AAGAGCAAAGAAGCTTTAATTCAGTGCCTTAAAGAGGAGAAATCTCAGATGGCATGTCCTGATGAGAAT GTGTCATCTGGAGAGCTCCGAGGACTTTGTGCTGCTCCAAGGGAAGAAAAGGAGAGAGAAACTGAGGCT GCACAAATGGAGCATCAGAAGGAGAGAAACAGCTTTGAAGAGAGGATCCAGGCACTTGAAGAGGACCTG AGAGAGAAGGAAAGAGAAATTGCTACAGAGAAGAAAAATAGTCTAAAGAGGGATAAAGCCATTCAGGGT TTAACCATGGCATTAAAATCAAAGGAAAAAAAGGTTGAAGAACTTAACTCTGAAATTGAAAAGCTCAGT GCTGCCTTTGCTAAAGCCAGAGAGGCCCTACAGAAAGCACAGACCCAGGAATTTCAGGGGTCTGAAGAC TATGAGACTGCTCTATCAGGAAAGGAAGCCCTTTCGGCTGCGCTGCGCTCACAAAACCTCACCAAGAGT ACAGAGAACCACAGACTGCGTAGAAGCATTAAGAAGATCACCCAGGAGCTGAGTGACTTGCAGCAGGAG AGGGAGAGACTGGAGAAGGACCTGGAGGAAGCCCATCGAGAGAAGAGCAAAGGAGACTGCACCATCCGT GATCTTAGAAATGAAGTTGAAAAATTACGCAATGAAGTGAATGAAAGAGAGAAAGCAATGGAAAATCGT TACAAGAGTCTTCTGAGTGAAAGCAATAAAAAATTGCACAATCAAGAGCAAGTGATCAAACATCTAACA GAAAGTACCAATCAGAAGGACGTGTTGCTTCAGAAATTCAATGAAAAAGATTTGGAAGTAATACAGCAG AACTGCTATTTAATGGCTGCAGAGGATCTTGAGCTCAGGAGTGAAGGCTTAATAACAGAAAAGTGCTCT TCTCAACAGCCACCAGGCAGCAAAACCATCTTCTCTAAGGAAAAGAAACAATCATCAGACTATGAAGAG CTGATTCAGGTCTTAAAGAAAGAGCAGGACATCTATACCCATCTGGTCAAATCTCTGCAGGAATCAGAC AGTATCAACAACCTGCAGGCTGAGTTAAACAAGATTTTTGCCCTGCGGAAGCAACTGGAGCAGGATGTG CTTTCATATCAGAATTTGCGGAAGACCTTGGAGGAGCAGATCAGCGAAATTCGGAGGCGGGAAGAATCA TTTTCACTTTATAGTGATCAAACATCTTATCTAAGTATTTGCCTTGAAGAAAACAATCGGTTTCAAGTG GAACATTTTTCTCAAGAAGAACTTAAGAAAAAGGTCAGTGACCTTATACAGCTAGTGAAGGAGCTGTAT ACAGACAACCAGCACCTGAAGAAAACCATTTTTGATCTCTCCTGCATGGGTTTCCAGGGAAATGGGTTT CCAGATAGACTTGCGTCTACAGAACAAACAGAGGAGGCTAAGAAGTCCCGCTTGCCAATCCTAATAAAA CCATCCCGGTCATTAGGAAATATGTATCGTCTCCCTGCCACCCAGGAGGTGGTGACGCAGCTGCAGAGC CAGATCTTGGAGCTGCAGGGGGAGCTGAAGGAGTTTAAAACTTGTAATAAGCAACTTCACCAAAAGTTA ATTCTGGCTGAAGCAGTGATGGAGGGGAGGCCAACGCCCGACAAAACGTTGCTGAATGCTCAGCCCCCT GTGGGAGCAGCCTACCAGGACAGCCCAGGAGAGCAGAAAGGAATTAAAACCACATCTTCTGTCTGGAGA GACAAGGAAATGGACAGTGATCAGCAAAGAAGCTACGAGATTGACTCTGAGATTTGCCCACCTGATGAC CTTGCCAGCTTGCCATCATGCAAAGAAAATCCTGAAGATGTTCTGAGCCCAACTTCAGTAGCTACTTAC CTGAGTTCCAAGAGTCAGCCTTCTGCTAAAGTCAGTGTGATGGGGACTGATCAGTCAGAGAGCATTAAT ACCTCAAATGAGACAGAATACTTAAAACAGAAAATCCATGACTTGGAAACTGAGCTGGAAGGCTACCAG AATTTCATATTTCAGCTTCAAAAGCACTCCCAGTGCAGTGAGGCCATAATTACAGTTTTGTGTGGGACA GAAGGGGCCCAGGATGGCTTGAGCAAGCCCAAGAATGGTTCTGATGGGGAAGAAATGACCTTTTCAAGT TTGCACCAAGTGCGATACGTGAAACACGTGAAAATCCTCGGTCCGCTGGCCCCAGAGATGATTGACAGC AGGGTGCTGGAGAACCTCAAACAGCAGCTGGAGGAACAGGAATACAAGCTGCAGAAGGAGCAGAATTTG AACATGCAACTTTTCAGTGAGATCCATAATCTGCAGAATAAGTTCAGAGATCTCTCACCTCCCAGATAC GATTCATTAGTTCAGTCCCAAGCCAGGGAGCTCTCCCTTCAACGGCAGCAGATTAAGGATGGCCATGGC ATCTGTGTCATCTCCCGTCAACACATGAACACCATGATTAAGGCATTTGAGGAGTTGCTGCAGGCCAGT GATGTGGATTACTGTGTGGCCGAGGGTTTCCAGGAACAGCTGAATCAATGTGCTGAGCTGCTGGAGAAA TTGGAAAAGCTATTTCTCAACGGAAAATCAGTTGGAGTGGAAATGAACACCCAGAATGAACTGATGGAG AGGATTGAGGAAGACAACTTAACCTACCAACATCTTCTGCCTGAATCTCCTGAGCCTTCAGCCTCTCAT GCGCTCTCTGATTATGAAACATCTGAAAAGTCCTTCTTCTCACGAGACCAGAAGCAAGATAATGAGACA GAGAAGACTTCAGTTATGGTGAACAGTTTTTCTCAAGACTTACTAATGGAACACATACAGGAAATTCGA ACTTTGAGAAAGCGTTTAGAAGAATCTATTAAAACAAATGAGAAGCTACGGAAACAGTTGGAACGGCAA GGATCTGAATTTGTTCAAGGTTCTACAAGCATTTTTGCTTCTGGTTCAGAGCTTCATAGTTCTCTAACA TCAGAAATTCATTTCTTGAGGAAGCAGAACCAGGCCCTCAATGCAATGCTCATTAAAGGATCCAGAGAT AAACAGAAGGAGAATGACAAATTACGAGAGTCCCTCTCCAGGAAGACCGTGAGCCTGGAGCACCTTCAG CGGGAGTATGCCAGCGTGAAGGAAGAAAATGAAAGGCTGCAGAAAGAAGGCAGCGAGAAGGAGAGACAC AACCAGCAGCTGATCCAGGAGGTCCGCTGCAGCGGCCAGGAGCTGAGCAGGGTGCAGGAGGAGGTGAAG TTGAGGCAGCAGCTGCTCTCACAGAATGACAAGCTATTGCAGTCTCTCCGAGTGGAGCTGAAGGCGTAT GAGAAGCTGGATGAAGAGCACAGGAGACTGAGAGAGGCGTCGGGAGAAGGCTGGAAGGGGCAGGATCCT TTCAGGGACCTGCACAGCCTCCTGATGGAGATCCAGGCTCTGCGCTTGCAACTAGAAAGGAGCATCGAA ACCAGCAGCACTCTGCAGAGCAGGCTCAAGGAACAGCTGGCAAGGGGGGCAGAGAAGGCACAGGAAGGA GCCCTCACTCTGGCTGTCCAAGCCGTGTCCATCCCTGAGGTGCCCCTTCAGCCTGACAAACACGATGGT GACAAATATCCCATGGAAAGTGATAATTCATTTGATCTGTTTGATTCCTCCCAGGCAGTGACACCAAAA TCAGTTTCAGAGACTCCTCCACTCTCTGGGAATGACACGGACTCCCTCTCCTGCGACAGTGGCAGTTCG GCAACTAGCACTCCGTGTGTGTCCCGCCTGGTCACTGGCCACCACCTGTGGGCCAGCAAGAATGGCCGC CATGTCCTGGGCCTGATTGAGGACTATGAGGCCCTGCTCAAACAGATCAGCCAGGGACAGAGGCTCCTT GCTGAAATGGACATTCAAACCCAAGAGGCTCCCAGCTCCACAAGTCAAGAGCTGGGAACAAAGGGTCCA CACCCAGCACCACTGAGCAAGTTTGTGAGCAGTGTGAGCACGGCCAAGCTGACCCTGGAAGAGGCCTAC AGGCGGCTGAAGCTTCTCTGGAGAGTCTCACTCCCCGAGGATGGCCAGTGCCCCCTTCACTGTGAGCAG ATTGGAGAAATGAAGGCAGAGGTCACCAAACTACATAAAAAATTGTTTGAACAAGAAAAGAAGTTGCAA AACACCATGAAGCTTTTGCAGCTGAGCAAGCGCCAGGAAAAAGTCATCTTTGATCAATTGGTCGTAACC CACAAAATCCTTCGGAAGGCCAGAGGAAACCTGGAGCTTAGGCCTGGGGGAGCCCATCCAGGAACATGC AGTCCCAGCAGACCAGGCTCCTGA
Restriction Sites	SgfI-MluI
ACCN	NM_001272039
Insert Size	4992 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	NM_001272039.1
RefSeq Size	5552 bp
RefSeq ORF	4992 bp
Locus ID	55755
UniProt ID	Q96SN8
MW	189.6 kDa
Gene Summary	This gene encodes a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein encoded by this gene is localized to the centrosome and Golgi complex, interacts with CDK5R1 and pericentrin (PCNT), plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013] Transcript Variant: This variant (3) uses an alternate in-frame splice site and lacks three in-frame exons in the coding region, compared to variant 1. The encoded isoform (c) is shorter compared to isoform a.

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.