RGS20 (NM_001286673) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	g(z)GAP; gz-GAP; RGSZ1; ZGAP1
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for NM_001286673, the custom clone sequence may differ by one or more nucleotides ATGCCCCAGCTTTCCCAAGATAACCAAGAGTGCCTCCAGAAACATTTCTCCAGGCCGTCTATATGGACAC AGTTTCTGCCCCTGTTCAGGGCTCAGAGATATAATACAGACATTCACCAAATCACAGAAAATGAAGGAGA CCTCAGGGCTGTTCCTGATATCAAGCAGATGGGATCAGAGCGGATGGAGATGCGGAAGCGGCAGATGCCC GCCGCCCAGGACACACCAGGCGCCGCCCCAGGCCAGCCCGGAGCGGGGAGTCGCGGGTCCAACGCATGCT GCTTCTGCTGGTGCTGCTGTTGTAGCTGCTCGTGTCTCACTGTTAGAAACCAGGAAGATCAGAGGCCCAC AATAGCTTCCCACGAACTCAGAGCAGATCTTCCAACCTGGGAAGAAAGCCCTGCTCCTACTCTGGAAGAA GTCAACGCCTGGGCTCAGTCATTTGACAAATTAATGGTCACTCCAGCAGGAAGGAATGCATTCCGTGAAT TCCTCCGAACAGAATTCAGTGAGGAAAATATGCTCTTCTGGATGGCCTGTGAGGAACTGAAAAAGGAAGC TAATAAAAACATTATTGAAGAGAAAGCAAGGATAATCTATGAAGACTACATTTCTATACTTTCTCCTAAG GAGGTGAGCTTAGACTCCCGGGTGAGAGAAGTGATCAACAGAAACATGGTGGAGCCATCCCAACACATAT TCGATGATGCTCAACTTCAGATTTACACCCTGATGCACAGAGACTCATATCCTCGATTCATGAACTCTGC TGTCTATAAGGACTTGCTTCAGTCCTTATCGGAGAAATCTATTGAAGCATAG
Restriction Sites	SgfI-MluI
ACCN	NM_001286673
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001286673.1, NP_001273602.1
RefSeq Size	1760 bp
RefSeq ORF	822 bp
Locus ID	8601
UniProt ID	O76081
Protein Families	Druggable Genome
Gene Summary	The protein encoded by this gene belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] Transcript Variant: This variant (3) lacks an in-frame exon in the 5' coding region comapred to variant 1. The encoded isoform (c) is shorter than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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