LSP1 (NM_001289005) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	pp52; WP34
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for NM_001289005, the custom clone sequence may differ by one or more nucleotides ATGCTCCTCAGCCTGAAGCCCTCGGAGGCCCCTGAACTGGATGAGGACGAGGGCTTTGGCGACTGGTCCC AGAGGCCAGAGCAGCGGCAGCAGCACGAGGGGGCGCAGGGCGCCTTGGACAGCGGAGAGCCCCCCCAGTG CAGGAGTCCTGAGGGGGAGCAAGAGGACAGGCCCGGCCTGCATGCCTACGAAAAGGAGGACAGTGATGAA GTCCACCTGGAGGAGTTGAGTCTGAGCAAGGAGGGGCCAGGCCCAGAGGACACTGTCCAGGACAACCTGG GGGCCGCAGGGGCTGAGGAGGAACAGGAGGAGCACCAGAAATGTCAGCAGCCCAGGACACCCAGCCCCTT GGTCTTGGAGGGGACCATCGAACAGAGCTCGCCTCCCCTGAGCCCTACCACCAAACTCATCGACAGGACC GAGTCCCTAAACCGCTCCATAGAGAAGAGTAACAGTGTGAAGAAATCCCAGCCAGACTTGCCCATCTCCA AGATTGATCAGTGGCTGGAACAATACACCCAGGCCATCGAGACCGCTGGCCGGACCCCCAAGCTAGCCCG CCAGGCCTCCATAGAGCTGCCCAGCATGGCTGTGGCCAGTACCAAGAGTCGGTGGGAGACGGGTGAGGTA CAGGCTCAGTCTGCGGCCAAGACTCCGTCCTGCAAGGATATTGTGGCTGGAGACATGAGCAAGAAAAGCC TCTGGGAGCAGAAGGGAGGCTCCAAGACCTCATCAACAATTAAGAGCACCCCATCTGGGAAGAGGTATAA GTTTGTGGCCACCGGGCATGGGAAGTATGAGAAGGTGCTTGTGGAAGGGGGCCCGGCTCCCTAG
Restriction Sites	SgfI-MluI
ACCN	NM_001289005
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001289005.1, NP_001275934.1
RefSeq Size	1882 bp
RefSeq ORF	834 bp
Locus ID	4046
UniProt ID	P33241
Gene Summary	This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (6) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 5. The resulting isoform (2) has a shorter N-terminus, compared to isoform 3. Variants 2, 3, 4 and 6 encode the same protein (isoform 2).

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