DNASE1L2 (NM_001301680) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	DNAS1L2
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC335188 representing NM_001301680. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGGGCGGGCCCCGGGCTCTGCTGGCCGCACTCTGGGCGCTGGAAGCCGCCGGGACCGCCGCGCTTCGC ATCGGAGCCTTCAACATTCAGAGCTTCGGTGACAGCAAAGTGTCGGACCCCGCTTGCGGCAGCATCATC GCGAAGATCCTGGCTGGCTATGACCTCGCGCTGGTGCAGGAGGTGCGAGACCCAGACCTCAGCGCCGTG TCCGCGCTCATGGAGCAGATCAACAGCGTGTCCGAGCACGAGTACAGCTTTGTGAGCAGCCAGCCCCTG GGCCGGGACCAGTACAAGGAGATGTACCTGTTCGTGTACAGGAAAGACGCGGTGTCGGTCGTGGACACC TACCTGTACCCAGACCCCGAGGACGTCTTCAGCCGCGAGCCCTTCGTGGTCAAGTTCTCGGCCCCCGGC ACCGGTGAGCGGGCCCCGCCCCTCCCCTCCCGCCGAGCTCTGACGCCCCCACCCCTTCCCGCAGCAGCA CAGAACCTGGTGCTGATCCCGCTGCACGCGGCGCCGCATCAAGCCGTGGCGGAGATCGACGCGCTCTAC GACGTGTACCTGGACGTGATCGACAAGTGGGGCACCGACGACATGCTGTTCCTGGGCGACTTCAACGCC GACTGCAGCTATGTGCGGGCGCAGGACTGGGCCGCCATCCGTCTGAGGAGCAGTGAGGTCTTCAAGTGG CTCATCCCTGACAGCGCCGACACCACGGTGGGCAACTCAGACTGCGCCTACGACCGCATTGTGGCCTGT GGCGCCCGCCTGCGCCGGAGCCTGAAGCCCCAGTCGGCCACCGTGCACGACTTCCAGGAGGAATTCGGC CTGGACCAGACTCAGGCTCTTGCCATCAGCGACCACTTTCCAGTGGAGGTGACCCTCAAGTTCCACCGA TGA
Restriction Sites	SgfI-MluI
ACCN	NM_001301680
Insert Size	900 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001301680.1
RefSeq Size	1342 bp
RefSeq ORF	900 bp
Locus ID	1775
UniProt ID	Q92874
Protein Families	Secreted Protein
MW	32.9 kDa
Gene Summary	Divalent cation-dependent acid DNA endonuclease involved in the breakdown of the nucleus during corneocyte formation of epidermal keratinocytes. May play an immune role by eliminating harmful DNA released into the extracellular environment by damaged epidermal cells.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.

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