Heme oxygenase 2 (HMOX2) (NM_001286267) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	HO-2
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >SC335675 representing NM_001286267. Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGAGTCTCGCTCTGTTGCCCAGGCTGGAGTGCAGTGGATCAGTCTAGCTCATTGCAGCCTCCACCTC CTGGGTTCAAGAGATTCTCCTGCCTCAGCCTCCTGTGTAGCTGGGATTACAGGACCAGAGGAGCGAGAG CAGCAAGAACCACACCCAGCAGCAATGTCAGCGGAAGTGGAAACCTCAGAGGGGGTAGACGAGTCAGAA AAAAAGAACTCTGGGGCCCTAGAAAAGGAGAACCAAATGAGAATGGCTGACCTCTCGGAGCTCCTGAAG GAAGGGACCAAGGAAGCACACGACCGGGCAGAAAACACCCAGTTTGTCAAGGACTTCTTGAAAGGCAAC ATTAAGAAGGAGCTGTTTAAGCTGGCCACCACGGCACTTTACTTCACATACTCAGCCCTCGAGGAGGAA ATGGAGCGCAACAAGGACCATCCAGCCTTTGCCCCTTTGTACTTCCCCATGGAGCTGCACCGGAAGGAG GCGCTGACCAAGGACATGGAGTATTTCTTTGGTGAAAACTGGGAGGAGCAGGTGCAGTGCCCCAAGGCT GCCCAGAAGTACGTGGAGCGGATCCACTACATAGGGCAGAACGAGCCGGAGCTACTGGTGGCCCATGCA TACACCCGCTACATGGGGGATCTCTCGGGGGGCCAGGTGCTGAAGAAGGTGGCCCAGCGAGCACTGAAA CTCCCCAGCACAGGGGAAGGGACCCAGTTCTACCTGTTTGAGAATGTGGACAATGCCCAGCAGTTCAAG CAGCTCTACCGGGCCAGGATGAACGCCCTGGACCTGAACATGAAGACCAAAGAGAGGATCGTGGAGGAG GCCAACAAGGCTTTTGAGTATAACATGCAGATATTCAATGAACTGGACCAGGCCGGCTCCACACTGGCC AGAGAGACCTTGGAGGATGGGTTCCCTGTACACGATGGGAAAGGAGACATGCGTAAATGCCCTTTCTAC GCTGCTGAACAAGACAAAGGTGCCCTGGAGGGCAGCAGCTGTCCCTTCCGAACAGCTATGGCTGTGCTG AGGAAGCCCAGCCTCCAGTTCATCCTGGCCGCTGGTGTGGCCCTAGCTGCTGGACTCTTGGCCTGGTAC TACATGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC
Restriction Sites	SgfI-MluI
ACCN	NM_001286267
Insert Size	1113 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001286267.1
RefSeq Size	1875 bp
RefSeq ORF	1113 bp
Locus ID	3163
UniProt ID	P30519
Protein Families	Transmembrane
Protein Pathways	Porphyrin and chlorophyll metabolism
MW	41.7 kDa
Gene Summary	Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. Several alternatively spliced transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2013] Transcript Variant: This variant (5) encodes the longest isoform (a).

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.