P protein (OCA2) (NM_001300984) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	BEY; BEY1; BEY2; BOCA; D15S12; EYCL; EYCL2; EYCL3; HCL3; P; PED; SHEP1
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for NM_001300984, the custom clone sequence may differ by one or more nucleotides ATGCATCTGGAGGGCAGAGACGGCAGGCGGTACCCCGGCGCGCCGGCGGTGGAGCTCCTGCAGACGTCCG TGCCCAGCGGACTCGCTGAACTTGTGGCCGGCAAGCGCAGGCTTCCTCGGGGAGCCGGTGGAGCTGACCC CTCGCACTCCTGCCCCAGGGGGGCTGCCGGGCAGAGCTCTTGGGCTCCTGCAGGCCAGGAGTTTGCTTCA TTCCTCACAAAAGGGAGGTCTCACTCTTCTTTGCCCCAGATGTCCAGCTCCAGGTCTAAAGATTCCTGCT TTACAGAAAACACTCCTTTGCTGAGGAATTCCTTACAGGAGAAAGGGTCACGGTGCATACCTGTTTACCA TCCAGAGTTCATCACTGCTGAAGAGTCTTGGGAAGACAGCTCTGCTGACTGGGAGCGAAGATACCTGCTA AGCAGGGAGGTGTCTGGTCTGTCTGCATCTGCCTCCTCCGAGAAGGGAGACCTTCTGGACAGCCCGCACA TCCGACTCCGTCTTTCCAAGCTGAGGCGCTGTGTGCAGTGGCTGAAAGTCATGGGCCTGTTTGCCTTTGT GGTGCTGTGTTCTATTTTGTTCAGCCTATATCCGGATCAAGGAAAGCTCTGGCAGCTGTTGGCCTTATCA CCGCTGGAGAACTACTCCGTGAACCTTAGCAGCCACGTGGACTCCACGCTGCTGCAGGTGGACCTGGCAG GGGCCCTAGTGGCCAGTGGGCCGAGTCGTCCTGGGAGGGAAGAGCACATCGTGGTGGAGCTGACCCAGGC TGACGCTTTGGGCTCCAGGTGGCGGCGGCCACAGCAGGTCACTCACAACTGGACGGTGTATTTAAATCCG AGGAGAAGCGAGCACTCAGTGATGAGCAGGACCTTTGAGGTACTGACCAGAGAGACGGTGTCCATCAGCA TCCGGGCCTCCCTGCAGCAGACCCAGGCTGTCCCTCTTTTGATGGCTCATCAGTACCTCCGCGGAAGTGT AGAAACCCAGGTGACCATCGCGACGGCCATCCTCGCGGGCGTCTACGCGCTGATCATATTTGAGAGACCC AGCCTGACCCATGTGGTGGAGTGGATTGATTTTGAGACGCTGGCCCTGCTGTTTGGCATGATGATCTTAG TAGCCATATTTTCAGAAACGGGATTTTTCGATTATTGTGCTGTAAAGGCATACCGGCTCTCCCGGGGACG GGTGTGGGCCATGATCATCATGCTCTGTCTCATCGCGGCCGTCCTCTCTGCCTTCTTGGACAACGTCACC ACCATGCTCCTCTTCACGCCTGTGACCATAAGGTTGTGTGAGGTGCTCAACCTTGATCCAAGACAAGTCC TGATTGCAGAAGTGATCTTCACAAACATTGGAGGAGCTGCCACTGCCATCGGGGACCCTCCAAATGTCAT TATTGTTTCCAACCAAGAGCTGAGGAAGATGGGCCTGGACTTTGCCGGATTCACTGCACACATGTTCATT GGGATTTGCCTTGTTCTCCTGGTCTGCTTTCCGCTCCTCAGACTCCTTTACTGGAACAGAAAGCTTTATA ACAAGGAACCCAGTGAGATTGTTGAACTGAAGCACGAGATTCACGTCTGGCGCCTGACTGCTCAGCGCAT CAGCCCGGCCAGCCGCGAGGAGACAGCTGTGCGCCGCCTGCTGCTGGGGAAGGTGCTGGCACTGGAGCAC CTGCTCGCCCGGAGGCTGCACACCTTCCACAGACAGATCTCACAGGAGGACAAAAATTGGGAGACCAATA TCCAAGAACTCCAAAAAAAGCATAGGATATCTGACGGGATTCTGCTCGCCAAATGCCTGACAGTGTTGGG ATTTGTTATCTTCATGTTTTTCCTCAATTCGTTTGTCCCTGGCATTCATCTTGATCTTGGATGGATTGCT ATTCTGGGTGCCATCTGGTTGCTAATTTTAGCTGATATTCATGATTTTGAGATAATTCTACACAGAGTGG AATGGGCAACCCTTCTGTTTTTTGCAGCGCTCTTTGTTCTGATGGAGGCATTGGCACATCTCCACTTAAT AGAATATGTTGGAGAACAAACTGCTTTGCTAATAAAGATGGTCCCAGAGGAGCAGCGCCTCATAGCCGCC ATTGTCCTGGTGGTGTGGGTCTCAGCCCTGGCGTCGTCCCTGATTGACAACATCCCGTTCACTGCTACCA TGATTCCCGTGCTCCTGAACCTGAGCCACGACCCTGAGGTTGGCCTGCCCGCACCGCCGCTCATGTATGC CCTGGCCTTCGGTGCTTGCCTGGGAGGTAACGGGACACTGATTGGCGCGTCGGCAAACGTCGTGTGTGCA GGGATTGCAGAACAGCATGGATATGGGTTCTCCTTCATGGAATTTTTCAGGCTGGGCTTCCCAATGATGG TTGTGTCCTGCACTGTTGGGATGTGTTATCTCCTTGTGGCTCATGTGGTGGTGGGATGGAATTAA
Restriction Sites	SgfI-MluI
ACCN	NM_001300984
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	NM_001300984.1, NP_001287913.1
RefSeq Size	3082 bp
RefSeq ORF	2445 bp
Locus ID	4948
UniProt ID	Q04671
Protein Families	Druggable Genome, Transmembrane
Gene Summary	This gene encodes the human homolog of the mouse p (pink-eyed dilution) gene. The encoded protein is believed to be an integral membrane protein involved in small molecule transport, specifically tyrosine, which is a precursor to melanin synthesis. It is involved in mammalian pigmentation, where it may control skin color variation and act as a determinant of brown or blue eye color. Mutations in this gene result in type 2 oculocutaneous albinism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] Transcript Variant: This variant (2) lacks an alternate in-frame exon in the central coding region, compared to variant 1, resulting in an isoform (2) that is shorter than isoform 1.

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