KIF20B (NM_001284259) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	CT90; KRMP1; MPHOSPH1; MPP-1; MPP1
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for NM_001284259, the custom clone sequence may differ by one or more nucleotides ATGGAATCTAATTTTAATCAAGAGGGAGTACCTCGACCATCTTATGTTTTTAGTGCTGACCCAATTGCAA GGCCTTCAGAAATAAATTTCGATGGCATTAAGCTTGATCTGTCTCATGAATTTTCCTTAGTTGCTCCAAA TACTGAGGCAAACAGTTTCGAATCTAAAGATTATCTCCAGGTTTGTCTTCGAATAAGACCATTTACACAG TCAGAAAAAGAACTTGAGTCTGAGGGCTGTGTGCATATTCTGGATTCACAGACTGTTGTGCTGAAAGAGC CTCAATGCATCCTTGGTCGGTTAAGTGAAAAAAGCTCAGGGCAGATGGCACAGAAATTCAGTTTTTCCAA GGTTTTTGGCCCAGCAACTACACAGAAGGAATTCTTTCAGGGTTGCATTATGCAACCAGTAAAAGACCTC TTGAAAGGACAGAGTCGTCTGATTTTTACTTACGGGCTAACCAATTCAGGAAAAACATATACATTTCAAG GGACAGAAGAAAATATTGGCATTCTGCCTCGAACTTTGAATGTATTATTTGATAGTCTTCAAGAAAGACT GTATACAAAGATGAACCTTAAACCACATAGATCCAGAGAATACTTAAGGTTATCATCAGAACAAGAGAAA GAAGAAATTGCTAGCAAAAGTGCATTGCTTCGGCAAATTAAAGAGGTTACTGTGCATAATGATAGTGATG ATACTCTTTATGGAAGTTTAACTAACTCTTTGAATATCTCAGAGTTTGAAGAATCCATAAAAGATTATGA ACAAGCCAACTTGAATATGGCTAATAGTATAAAATTTTCTGTGTGGGTTTCTTTCTTTGAAATTTACAAT GAATATATTTATGACTTATTTGTTCCTGTATCATCTAAATTCCAAAAGAGAAAGATGCTGCGCCTTTCCC AAGACGTAAAGGGCTATTCTTTTATAAAAGATCTACAATGGATTCAAGTATCTGATTCCAAAGAAGCCTA TAGACTTTTAAAACTAGGAATAAAGCACCAGAGTGTTGCCTTCACAAAATTGAATAATGCTTCCAGTAGA AGTCACAGCATATTCACTGTTAAAATATTACAGATTGAAGATTCTGAAATGTCTCGTGTAATTCGAGTCA GTGAATTATCTTTATGTGATCTTGCTGGTTCAGAACGAACTATGAAGACACAGAATGAAGGTGAAAGGTT AAGAGAGACTGGGAATATCAACACTTCTTTATTGACTCTGGGAAAGTGTATTAACGTCTTGAAGAATAGT GAAAAGTCAAAGTTTCAACAGCATGTGCCTTTCCGGGAAAGTAAACTGACTCACTATTTTCAAAGTTTTT TTAATGGTAAAGGGAAAATTTGTATGATTGTCAATATCAGCCAATGTTATTTAGCCTATGATGAAACACT CAATGTATTGAAGTTCTCCGCCATTGCACAAAAAGTTTGTGTCCCAGACACTTTAAATTCCTCTCAAGAG AAATTATTTGGACCTGTCAAATCTTCTCAAGATGTATCACTAGACAGTAATTCAAACAGTAAAATATTAA ATGTAAAAAGAGCCACCATTTCATGGGAAAATAGTCTAGAAGATTTGATGGAAGACGAGGATTTGGTTGA GGAGCTAGAAAACGCTGAAGAAACTCAAAATGTGGAAACTAAACTTCTTGATGAAGATCTAGATAAAACA TTAGAGGAAAATAAGGCTTTCATTAGCCACGAGGAGAAAAGAAAACTGTTGGACTTAATAGAAGACTTGA AAAAAAAACTGATAAATGAAAAAAAGGAAAAATTAACCTTGGAATTTAAAATTCGAGAAGAAGTTACACA GGAGTTTACTCAGTATTGGGCTCAACGGGAAGCTGACTTTAAGGAGACTCTGCTTCAAGAACGAGAGATA TTAGAAGAAAATGCTGAACGTCGTTTGGCTATCTTCAAGGATTTGGTTGGTAAATGTGACACTCGAGAAG AAGCAGCGAAAGACATTTGTGCCACAAAAGTTGAAACTGAAGAAACACATAATTATGTAGGATTTGAAGA TATTATTGATTCTCTTCAAGATAATGTTGCTGATATTAAGAAACAGGCTGAAATTGCTCACTTATATATT GCATCTCTTCCTGACCCCCAGGAAGCTACTGCTTGTTTAGAACTAAAGTTTAATCAAATTAAAGCTGAAT TAGCTAAAACCAAAGGAGAATTAATCAAAACCAAAGAAGAGTTAAAAAAGAGAGAAAATGAATCAGATTC ATTGATTCAAGAGCTTGAGACATCTAATAAGAAAATAATTACACAGAATCAAAGAATTAAAGAATTGATA AATATAATTGATCAAAAAGAAGATACTATCAACGAATTTCAGAACCTAAAGTCTCATATGGAAAACACAT TTAAATGCAATGACAAGGCTGATACATCTTCTTTAATAATAAACAATAAATTGATTTGTAATGAAACAGT TGAAGTACCTAAGGACAGCAAATCTAAAATCTGTTCAGAAAGAAAAAGAGTAAATGAAAATGAACTTCAG CAAGATGAACCACCAGCAAAGAAAGGGTCTATCCATGTTAGTTCAGCTATCACTGAAGACCAAAAGAAAA GTGAAGAAGTGCGACCGAACATTGCAGAAATTGAAGACATCAGAGTTTTACAAGAAAATAATGAAGGACT GAGAGCATTTTTACTCACTATTGAGAATGAACTTAAAAATGAAAAGGAAGAAAAAGCAGAATTAAATAAA CAGATTGTTCATTTTCAGCAGGAACTTTCTCTTTCTGAAAAAAAGAATTTAACTTTAAGTAAAGAGGTCC AACAAATTCAGTCAAATTATGATATTGCAATTGCTGAATTACATGTGCAGAAAAGTAAAAATCAAGAACA GGAGGAAAAGATCATGAAATTGTCAAATGAGATAGAAACTGCTACAAGAAGCATTACAAATAATGTTTCA CAAATAAAATTAATGCACACGAAAATAGACGAACTACGTACTCTTGATTCAGTTTCTCAGATTTCAAACA TAGATTTGCTCAATCTCAGGGATCTGTCAAATGGTTCTGAGGAGGATAATTTGCCAAATACACAGTTAGA CCTTTTAGGTAATGATTATTTGGTAAGTAAGCAAGTTAAAGAATATCGAATTCAAGAACCCAATAGGGAA AATTCTTTCCACTCTAGTATTGAAGCTATTTGGGAAGAATGTAAAGAGATTGTGAAGGCCTCTTCCAAAA AAAGTCATCAGATTGAGGAACTGGAACAACAAATTGAAAAATTGCAGGCAGAAGTAAAAGGCTATAAGGA TGAAAACAATAGACTAAAGGAGAAGGAGCATAAAAACCAAGATGACCTACTAAAAGAAAAAGAAACTCTT ATACAGCAGCTGAAAGAAGAATTGCAAGAAAAAAATGTTACTCTTGATGTTCAAATACAGCATGTAGTTG AAGGAAAGAGAGCGCTTTCAGAACTTACACAAGGTGTTACTTGCTATAAGGCAAAAATAAAGGAACTTGA AACAATTTTAGAGACTCAGAAAGTTGAATGTAGTCATTCAGCCAAGTTAGAACAAGACATTTTGGAAAAG GAATCTATCATCTTAAAGCTAGAAAGAAATTTGAAGGAATTTCAAGAACATCTTCAGGATTCTGTCAAAA ACACCAAAGATTTAAATGTAAAGGAACTCAAGCTGAAAGAAGAAATCACACAGTTAACAAATAATTTGCA AGATATGAAACATTTACTTCAATTAAAAGAAGAAGAAGAAGAAACCAACAGGCAAGAAACAGAAAAATTG AAAGAGGAACTCTCTGCAAGCTCTGCTCGTACCCAGAATCTGAAAGCAGATCTTCAGAGGAAGGAAGAAG ATTATGCTGACCTGAAAGAGAAACTGACTGATGCCAAAAAGCAGATTAAGCAAGTACAGAAAGAGGTATC TGTAATGCGTGATGAGGATAAATTACTGAGGATTAAAATTAATGAACTGGAGAAAAAGAAAAACCAGTGT TCTCAGGAATTAGATATGAAACAGCGAACCATTCAGCAACTCAAGGAGCAGTTAAATAATCAGAAAGTGG AAGAAGCTATACAACAGTATGAGAGAGCATGCAAAGATCTAAATGTTAAAGAGAAAATAATTGAAGACAT GCGAATGACACTAGAAGAACAGGAACAAACTCAGGTAGAACAGGATCAAGTGCTTGAGGCTAAATTAGAG GAAGTTGAAAGGCTGGCCACAGAATTGGAAAAATGGAAGGAAAAATGCAATGATTTGGAAACCAAAAACA ATCAAAGGTCAAATAAAGAACATGAGAACAACACAGATGTGCTTGGAAAGCTCACTAATCTTCAAGATGA GTTACAGGAGTCTGAACAGAAATATAATGCTGATAGAAAGAAATGGTTAGAAGAAAAAATGATGCTTATC ACTCAAGCGAAAGAAGCAGAGAATATACGAAATAAAGAGATGAAAAAATATGCTGAGGACAGGGAGCGTT TTTTTAAGCAACAGAATGAAATGGAAATACTGACAGCCCAGCTGACAGAGAAAGATAGTGACCTTCAAAA GTGGCGAGAAGAACGAGATCAACTGGTTGCAGCTTTAGAAATACAGCTAAAAGCACTGATATCCAGTAAT GTACAGAAAGATAATGAAATTGAACAACTAAAAAGGATCATATCAGAGACTTCTAAAATAGAAACACAAA TCATGGATATCAAGCCCAAACGTATTAGTTCAGCAGATCCTGACAAACTTCAAACTGAACCTCTATCGAC AAGTTTTGAAATTTCCAGAAATAAAATAGAGGATGGATCTGTAGTCCTTGACTCTTGTGAAGTGTCAACA GAAAATGATCAAAGCACTCGATTTCCAAAACCTGAGTTAGAGATTCAATTTACACCTTTACAGCCAAACA AAATGGCAGTGAAACACCCTGGTTGTACCACACCAGTGACAGTTAAGATTCCCAAGGCTCGGAAGAGGAA GAGTAATGAAATGGAGGAGGACTTGGTGAAATGTGAAAATAAGAAGAATGCTACACCCAGAACTAATTTG AAATTTCCTATTTCAGATGATAGAAATTCTTCTGTCAAAAAGGAACAAAAGGTTGCCATACGTCCATCAT CTAAGAAAACATATTCTTTACGGAGTCAGGCATCCATAATTGGTGTAAACCTGGCCACTAAGAAAAAAGA AGGAACACTACAGAAATTTGGAGACTTCTTACAACATTCTCCCTCAATTCTTCAATCAAAAGCAAAGAAG ATAATTGAAACAATGAGCTCTTCAAAGCTCTCAAATGTAGAAGCAAGTAAAGAAAATGTGTCTCAACCAA AACGAGCCAAACGGAAATTATACACAAGTGAAATTTCATCTCCTATTGATATATCAGGCCAAGTGATTTT AATGGACCAGAAAATGAAGGAGAGTGATCACCAGATTATCAAACGACGACTTCGAACAAAAACAGCCAAA TAA
Restriction Sites	SgfI-MluI
ACCN	NM_001284259
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	NM_001284259.1, NP_001271188.1
RefSeq Size	6459 bp
RefSeq ORF	5463 bp
Locus ID	9585
UniProt ID	Q96Q89
Protein Families	Druggable Genome
Gene Summary	Plus-end-directed motor enzyme that is required for completion of cytokinesis (PubMed:11470801, PubMed:12740395). Required for proper midbody organization and abscission in polarized cortical stem cells. Plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. Participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner. In the developing telencephalon, cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. Involved in cerebral cortex growth (By similarity). Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PubMed:17409436).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.