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Fhit (NM_010210) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR201063L4V
- LentiORF®
-
Lenti ORF particles, Fhit (GFP-tagged) - Mouse fragile histidine triad gene (Fhit), 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
| Product Data | |
| Product Name | Fhit (NM_010210) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | AW045638; Fra1; Fra14A2 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_010210 |
| ORF Size | 453 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR201063).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_010210.2, NP_034340.1 |
| RefSeq Size | 998 bp |
| RefSeq ORF | 453 bp |
| Locus ID | 14198 |
| Gene Summary | This gene encodes a member of the HIT family of proteins that are characterized by the presence of a histidine triad sequence. The encoded protein is a diadenosine triphosphate hydrolase enzyme that cleaves the P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. This locus is very fragile and has been found to be altered in different types of cancers. Mice lacking the encoded protein display increased susceptibility to spontaneous and induced tumors. Ectopic expression of the encoded protein in such knockout mice inhibits tumor development. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015] |
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