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Naa50 (NM_028108) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR201391L4V
- LentiORF®
-
Lenti ORF particles, Naa50 (GFP-tagged) - Mouse N(alpha)-acetyltransferase 50, NatE catalytic subunit (Naa50), 200ul, >10^7 TU/mL
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CNY 8,360.00
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规格
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Specifications
| Product Data | |
| Product Name | Naa50 (NM_028108) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 2600005K24Rik; 2810441M03Rik; AW112078; Mak3; Mak3p; Nat5; Nat13; San |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_028108 |
| ORF Size | 510 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR201391).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_028108.3 |
| RefSeq Size | 4526 bp |
| RefSeq ORF | 507 bp |
| Locus ID | 72117 |
| Gene Summary | N-alpha-acetyltransferase that acetylates the N-terminus of proteins that retain their initiating methionine. Has a broad substrate specificity: able to acetylate the initiator methionine of most peptides, except for those with a proline in second position. Also displays N-epsilon-acetyltransferase activity by mediating acetylation of the side chain of specific lysines on proteins. Autoacetylates in vivo. The relevance of N-epsilon-acetyltransferase activity is however unclear: able to acetylate H4 in vitro, but this result has not been confirmed in vivo. Component of a N-alpha-acetyltransferase complex containing NAA10 and NAA15, but NAA50 does not influence the acetyltransferase activity of NAA10: this multiprotein complex probably constitutes the major contributor for N-terminal acetylation at the ribosome exit tunnel, with NAA10 acetylating all amino termini that are devoid of methionine and NAA50 acetylating other peptides. Required for sister chromatid cohesion during mitosis by promoting binding of CDCA5/sororin to cohesin: may act by counteracting the function of NAA10.[UniProtKB/Swiss-Prot Function] |
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