Fcgr2b (NM_010187) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR204036L2V
- LentiORF®
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Lenti ORF particles, Fcgr2b (GFP-tagged) - Mouse Fc receptor, IgG, low affinity IIb (Fcgr2b), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
Product Data | |
Product Name | Fcgr2b (NM_010187) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | AI528646; CD32; F630109E10Rik; Fcgr2; Fcgr2a; FcgRII; Fcr-2; Fcr-3; fcRII; Fc[g]RII; Ly-17 |
Vector | pLenti-C-mGFP |
ACCN | NM_010187 |
ORF Size | 882 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR204036).
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OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_010187.2, NP_034317.1 |
RefSeq Size | 1415 bp |
RefSeq ORF | 882 bp |
Locus ID | 14130 |
Gene Summary | Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of antigen-antibody complexes from the circulation and modulation of antibody production by B-cells. Isoform IIB1 and isoform IIB1' form caps but fail to mediate endocytosis or phagocytosis. Isoform IIB2 can mediate the endocytosis of soluble immune complexes via clathrin-coated pits. Isoform IIB1 and isoform IIB2 can down-regulate B-cell, T-cell, and mast cell activation when coaggregated to B-cell receptors for AG (BCR), T-cell receptors for AG (TCR), and Fc receptors, respectively.[UniProtKB/Swiss-Prot Function] |
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