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Hmbox1 (BC051457) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR206358L3V
- LentiORF®
-
Lenti ORF particles, Hmbox1 (Myc-DDK-tagged) - Mouse homeobox containing 1 (cDNA clone MGC:56991 IMAGE:6398463), 200ul, >10^7 TU/mL
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CNY 9,975.00
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Specifications
| Product Data | |
| Product Name | Hmbox1 (BC051457) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | AI451877; AI604847; F830020C16Rik |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | BC051457 |
| ORF Size | 1212 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR206358).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | BC051457, AAH51457 |
| RefSeq Size | 3435 bp |
| RefSeq ORF | 1214 bp |
| Locus ID | 219150 |
| Gene Summary | Binds directly to 5'-TTAGGG-3' repeats in telomeric DNA (By similarity). Associates with the telomerase complex at sites of active telomere processing and positively regulates telomere elongation (By similarity). Important for TERT binding to chromatin, indicating a role in recruitment of the telomerase complex to telomeres (PubMed:23685356). Also plays a role in the alternative lengthening of telomeres (ALT) pathway in telomerase-negative cells where it promotes formation and/or maintenance of ALT-associated promyelocytic leukemia bodies (APBs) (By similarity). Enhances formation of telomere C-circles in ALT cells, suggesting a possible role in telomere recombination (By similarity). Might also be involved in the DNA damage response at telomeres (By similarity).[UniProtKB/Swiss-Prot Function] |
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