Sqstm1 (BC006019) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR206359L2V

  • LentiORF®

Lenti ORF particles, Sqstm1 (GFP-tagged) - Mouse sequestosome 1 (cDNA clone MGC:5968 IMAGE:3487289), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



Need custom lentivirus service?
Get a free quote

CNY 11,115.00


货期*
详询

规格
    • 200 ul

Product images

经常一起买 (3)
Lenti ORF control particles of pLenti-C-mGFP, >10^7 TU/mL, 0.5 mL
    • 500 ul

CNY 2,950.00


One-Wash Lentivirus Titer Kit, HIV-1 p24 ELISA
    • 96 reactions

CNY 5,230.00


SQSTM1 Rabbit pAb
    • 100 ul

CNY 2,640.00

Specifications

Product Data
Product Name Sqstm1 (BC006019) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms A170, STAP, OSF-6, p62
Vector pLenti-C-mGFP
ACCN BC006019
ORF Size 1212 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR206359).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq BC006019, AAH06019
RefSeq Size 2013 bp
RefSeq ORF 1214 bp
Locus ID 18412
Gene Summary Autophagy receptor required for selective macroautophagy (aggrephagy). Functions as a bridge between polyubiquitinated cargo and autophagosomes. Interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the autophagic machinery. Involved in midbody ring degradation (By similarity). May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (PubMed:14960283, PubMed:18382763). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels. Involved in endosome organization by retaining vesicles in the perinuclear cloud: following ubiquitination by RNF26, attracts specific vesicle-associated adapters, forming a molecular bridge that restrains cognate vesicles in the perinuclear region and organizes the endosomal pathway for efficient cargo transport (By similarity). Promotes relocalization of 'Lys-63'-linked ubiquitinated TMEM173/STING to autophagosomes (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
Customer Reviews 
Loading...