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Tgfb3 (NM_009368) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR206441L3V
- LentiORF®
-
Lenti ORF particles, Tgfb3 (Myc-DDK-tagged) - Mouse transforming growth factor, beta 3 (Tgfb3), 200ul, >10^7 TU/mL
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CNY 7,410.00
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规格
| Cited in 1 publication. |
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经常一起买 (2)
Specifications
| Product Data | |
| Product Name | Tgfb3 (NM_009368) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | TGF-beta-3; Tgfb-3 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_009368 |
| ORF Size | 1239 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR206441).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_009368.1, NP_033394.2 |
| RefSeq Size | 3401 bp |
| RefSeq ORF | 1239 bp |
| Locus ID | 21809 |
| Gene Summary | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Homozygous knockout mice for this gene exhibit cleft palate, delayed pulmonary development and neonatal death. [provided by RefSeq, Aug 2016] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Overexpression of Latent TGFβ Binding Protein 4 in Muscle Ameliorates Muscular Dystrophy through Myostatin and TGFβ
,null,
PLoS Genetics
,PubMed ID 27148972
[Tgfb3]
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