Tph1 (NM_009414) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR207141L4V
- LentiORF®
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Lenti ORF particles, Tph1 (GFP-tagged) - Mouse tryptophan hydroxylase 1 (Tph1), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 9,975.00
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Specifications
Product Data | |
Product Name | Tph1 (NM_009414) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | Tph |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_009414 |
ORF Size | 1344 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR207141).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_009414.2 |
RefSeq Size | 4581 bp |
RefSeq ORF | 1344 bp |
Locus ID | 21990 |
Gene Summary | This gene encodes a member of the biopterin-dependent aromatic amino acid hydroxylase family. The encoded protein is one of two tryptophan hydroxylase enzymes that catalyze the first and rate limiting step in the biosynthesis of the hormone and neurotransmitter, serotonin. This gene is expressed in peripheral organs, while tryptophan hydroxylase 2 is expressed in neurons. The encoded protein is involved in the development of hypoxia-induced elevations in pulmonary pressures and pulmonary vascular remodeling, and has also been implicated as a regulator of immune tolerance. Disruption of this gene is associated with cardiac dysfunction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013] |
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