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Mmp12 (NM_008605) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR207567L4V
- LentiORF®
-
Lenti ORF particles, Mmp12 (GFP-tagged) - Mouse matrix metallopeptidase 12 (Mmp12), 200ul, >10^7 TU/mL
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CNY 10,260.00
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Specifications
| Product Data | |
| Product Name | Mmp12 (NM_008605) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | AV378681; MME; Mmel; MMP1 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_008605 |
| ORF Size | 1419 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR207567).
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| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_008605.3, NP_032631.3 |
| RefSeq Size | 3607 bp |
| RefSeq ORF | 1422 bp |
| Locus ID | 17381 |
| Gene Summary | This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-dependent endopeptidase enzyme. Mice lacking the encoded protein have a diminished capacity to degrade extracellular matrix components, do not develop emphysema in response to long-term exposure to cigarette smoke, and exhibit impaired clearance and increased mortality upon bacterial infection. This gene is located in a cluster of other matrix metalloproteinase genes on chromosome 9. Alternate splicing generates multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2016] |
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