Tbxas1 (NM_011539) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR208546L4V
- LentiORF®
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Lenti ORF particles, Tbxas1 (GFP-tagged) - Mouse thromboxane A synthase 1, platelet (Tbxas1), 200ul, >10^7 TU/mL
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CNY 11,020.00
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规格
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Specifications
Product Data | |
Product Name | Tbxas1 (NM_011539) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | CYP5; CYP5A1; THAS; TS; TXAS; TXS |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_011539 |
ORF Size | 1602 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR208546).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_011539.3 |
RefSeq Size | 1992 bp |
RefSeq ORF | 1602 bp |
Locus ID | 21391 |
Gene Summary | Catalyzes the conversion of prostaglandin H2 (PGH2) to thromboxane A2 (TXA2), a potent inducer of blood vessel constriction and platelet aggregation. Cleaves also PGH2 to 12-hydroxy-heptadecatrienoicacid (12-HHT) and malondialdehyde, which is known to act as a mediator of DNA damage. 12-HHT and malondialdehyde are formed stoichiometrically in the same amounts as TXA2. Additionally, displays dehydratase activity, toward (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate (15(S)-HPETE) producing 15-KETE and 15-HETE.[UniProtKB/Swiss-Prot Function] |
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