Sh2b3 (NM_008507) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR208726L3V
- LentiORF®
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Lenti ORF particles, Sh2b3 (Myc-DDK-tagged) - Mouse SH2B adaptor protein 3 (Sh2b3), 200ul, >10^7 TU/mL
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CNY 10,070.00
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Specifications
Product Data | |
Product Name | Sh2b3 (NM_008507) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | AI429800; L; Lnk |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_008507 |
ORF Size | 1644 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR208726).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_008507.3 |
RefSeq Size | 2498 bp |
RefSeq ORF | 1647 bp |
Locus ID | 16923 |
Gene Summary | This gene encodes a member of the SH2B family of adapter proteins that play an important role in T cell receptor signaling. This gene is preferentially expressed in hematopoietic stem cells, hematopoietic progenitors, pre and immature B cells, as well as megakaryocytes and mastocytes. In hematopoietic stem cells, the encoded protein is a key regulator of self-renewal, proliferation and apoptosis. Mice lacking the encoded protein exhibit pre and immature B cell expansion in spleen and the bone marrow. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015] |
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