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Trim23 (BC059017) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR209027L4V
- LentiORF®
-
Lenti ORF particles, Trim23 (GFP-tagged) - Mouse tripartite motif protein 23 (cDNA clone MGC:69677 IMAGE:6848690), 200ul, >10^7 TU/mL
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CNY 11,115.00
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Specifications
| Product Data | |
| Product Name | Trim23 (BC059017) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 6330516O20Rik; AI450195; Arfd1 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | BC059017 |
| ORF Size | 1722 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR209027).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | BC059017, AAH59017 |
| RefSeq Size | 3385 bp |
| RefSeq ORF | 1724 bp |
| Locus ID | 81003 |
| Gene Summary | Acts as an E3 ubiquitin-protein ligase. Plays an essential role in autophagy activation during viral infection. Mechanistically, activates TANK-binding kinase 1/TBK1 by facilitating its dimerization and ability to phosphorylate the selective autophagy receptor SQSTM1. In order to achieve this function, TRIM23 mediates 'Lys-27'-linked auto-ubiquitination of its ADP-ribosylation factor (ARF) domain to induce its GTPase activity and its recruitment to autophagosomes.[UniProtKB/Swiss-Prot Function] |
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