Msn (NM_010833) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR209054L3V
- LentiORF®
Lenti ORF particles, Msn (Myc-DDK-tagged) - Mouse moesin (Msn), 200ul, >10^7 TU/mL
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CNY 10,355.00
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Specifications
Product Data | |
Product Name | Msn (NM_010833) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | C78546 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_010833 |
ORF Size | 1731 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR209054).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_010833.2, NP_034963.2 |
RefSeq Size | 3840 bp |
RefSeq ORF | 1734 bp |
Locus ID | 17698 |
Gene Summary | Ezrin-radixin-moesin (ERM) family protein that connects the actin cytoskeleton to the plasma membrane and thereby regulates the structure and function of specific domains of the cell cortex. Tethers actin filaments by oscillating between a resting and an activated state providing transient interactions between moesin and the actin cytoskeleton (By similarity). Once phosphorylated on its C-terminal threonine, moesin is activated leading to interaction with F-actin and cytoskeletal rearrangement (By similarity). These rearrangements regulate many cellular processes, including cell shape determination, membrane transport, and signal transduction (By similarity). The role of moesin is particularly important in immunity acting on both T and B-cells homeostasis and self-tolerance, regulating lymphocyte egress from lymphoid organs (PubMed:22875842). Modulates phagolysosomal biogenesis in macrophages (PubMed:28978692). Participates also in immunologic synapse formation (By similarity).[UniProtKB/Swiss-Prot Function] |
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