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Racgap1 (BC010715) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR209580L3V
- LentiORF®
-
Lenti ORF particles, Racgap1 (Myc-DDK-tagged) - Mouse Rac GTPase-activating protein 1 (cDNA clone MGC:11396 IMAGE:3602242), 200ul, >10^7 TU/mL
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CNY 9,975.00
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Specifications
| Product Data | |
| Product Name | Racgap1 (BC010715) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | Band25, GTPase, MgcRacGAP, gtl11 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | BC010715 |
| ORF Size | 1884 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR209580).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | BC010715, AAH10715 |
| RefSeq Size | 2913 bp |
| RefSeq ORF | 1886 bp |
| Locus ID | 26934 |
| Gene Summary | Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Required for proper attachment of the midbody to the cell membrane during cytokinesis. Plays key roles in controlling cell growth and differentiation of hematopoietic cells through mechanisms other than regulating Rac GTPase activity. Also involved in the regulation of growth-related processes in adipocytes and myoblasts. May be involved in regulating spermatogenesis and in the RACGAP1 pathway in neuronal proliferation. Shows strong GAP (GTPase activation) activity towards CDC42 and RAC1 and less towards RHOA. Essential for the early stages of embryogenesis. May play a role in regulating cortical activity through RHOA during cytokinesis. May participate in the regulation of sulfate transport in male germ cells.[UniProtKB/Swiss-Prot Function] |
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