Thoc1 (NM_153552) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR209815L4V

  • LentiORF®

Lenti ORF particles, Thoc1 (GFP-tagged) - Mouse THO complex 1 (Thoc1), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 12,635.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Thoc1 (NM_153552) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms 3110002N20Rik; AW107452; NMP-84
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_153552
ORF Size 1974 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR209815).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_153552.2
RefSeq Size 3855 bp
RefSeq ORF 1974 bp
Locus ID 225160
Gene Summary Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. Regulates transcriptional elongation of a subset of genes. Involved in genome stability by preventing co-transcriptional R-loop formation (By similarity).[UniProtKB/Swiss-Prot Function]
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