Trap1 (NM_026508) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR210158L3V
- LentiORF®
Lenti ORF particles, Trap1 (Myc-DDK-tagged) - Mouse TNF receptor-associated protein 1 (Trap1), 200ul, >10^7 TU/mL
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CNY 11,875.00
货期*
详询
规格
Cited in 1 publication. |
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经常一起买 (2)
Specifications
Product Data | |
Product Name | Trap1 (NM_026508) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | 2410002K23Rik; HSP75 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_026508 |
ORF Size | 2121 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR210158).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_026508.2, NP_080784.1 |
RefSeq Size | 2297 bp |
RefSeq ORF | 2121 bp |
Locus ID | 68015 |
Gene Summary | Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.[UniProtKB/Swiss-Prot Function] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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Inhibition of succinate dehydrogenase by the mitochondrial chaperone TRAP1 has anti-oxidant and anti-apoptotic effects on tumor cells
,null,
Oncotarget
,PubMed ID 25564869
[Trap1]
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