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Socs7 (NM_138657) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR216208L4V
- LentiORF®
-
Lenti ORF particles, Socs7 (GFP-tagged) - Mouse suppressor of cytokine signaling 7 (Socs7), 200ul, >10^7 TU/mL
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CNY 11,685.00
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Specifications
| Product Data | |
| Product Name | Socs7 (NM_138657) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 2310063P06Rik; C85125; Nap4 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_138657 |
| ORF Size | 1737 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR216208).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_138657.3, NP_619598.1 |
| RefSeq Size | 7015 bp |
| RefSeq ORF | 1740 bp |
| Locus ID | 192157 |
| Gene Summary | Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).[UniProtKB/Swiss-Prot Function] |
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