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Znrf1 (NM_001168623) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR216538L4V
- LentiORF®
-
Lenti ORF particles, Znrf1 (GFP-tagged) - Mouse zinc and ring finger 1 (Znrf1), transcript variant 4, 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
| Product Data | |
| Product Name | Znrf1 (NM_001168623) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | B830022L21Rik; nin283; Rnf42; Zrfp1 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_001168623 |
| ORF Size | 381 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR216538).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001168623.1 |
| RefSeq Size | 3650 bp |
| RefSeq ORF | 384 bp |
| Locus ID | 170737 |
| Gene Summary | E3 ubiquitin-protein ligase that mediates the ubiquitination of AKT1 and GLUL, thereby playing a role in neuron cells differentiation. Plays a role in the establishment and maintenance of neuronal transmission and plasticity. Regulates Schwann cells differentiation by mediating ubiquitination of GLUL. Promotes Wallerian degeneration, a neurodegeneration disorder, by mediating 'Lys-48'-linked polyubiquitination and subsequent degradation of AKT1 in axons: degradation of AKT1 prevents AKT1-mediated phosphorylation of GSK3B, leading to GSK3B activation and phosphorylation of DPYSL2/CRMP2 followed by destabilization of microtubule assembly in axons.[UniProtKB/Swiss-Prot Function] |
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