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Cbfa2t2 (NM_172860) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR217082L3V
- LentiORF®
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Lenti ORF particles, Cbfa2t2 (Myc-DDK-tagged) - Mouse core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human) (Cbfa2t2), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 10,545.00
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Specifications
| Product Data | |
| Product Name | Cbfa2t2 (NM_172860) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | A430091M07; C330013D05Rik; Cbfa2t2h; MTGR1 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_172860 |
| ORF Size | 1782 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR217082).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_172860.2, NP_766448.1 |
| RefSeq Size | 6100 bp |
| RefSeq ORF | 1785 bp |
| Locus ID | 12396 |
| Gene Summary | Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes. Via association with PRDM14 is involved in regulation of embryonic stem cell (ESC) pluripotency. Involved in primordial germ cell (PCG) formation (PubMed:27281218). Stabilizes PRDM14 and OCT4 on chromatin in a homooligomerization-dependent mannerCan repress the expression of MMP7 in a ZBTB33-dependent manner (By similarity). Through heteromerization with CBFA2T3/MTG16 may be involved in regulation of the proliferation and the differentiation of erythroid progenitors by repressing the expression of TAL1 target genes (PubMed:19799863). Required for the maintenance of the secretory cell lineage in the small intestine (PubMed:16227606). Can inhibit Notch signaling probably by association with RBPJ and may be involved in GFI1-mediated Paneth cell differentiation (PubMed:25398765).[UniProtKB/Swiss-Prot Function] |
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